High Dietary Fat Reduces the Rate of Pyruvate Supported Respiration in Isolated Cardiac Mitochondria. by Clair Crewe (467358)

“…<p>C57BL/6 mice were fed a control or high fat diet for 1 d to 20 wk. Cardiac mitochondria were then isolated and incubated at 0.25 mg/mL with 25 µM palmitoylcarnitine and 1.0 mM malate or 100 µM pyruvate and 1.0 mM malate as respiratory substrates. …”

Single channel recording of ELIC. by Iwan Zimmermann (117942)

“…(C) Current trace from a planar lipid bilayer containing at least two channels recorded at −100 mV in the presence of 2 mM cysteamine (recordings were filtered at 200 Hz). …”

Effect of central (i.c.v.) and peripheral (i.p.) injection of leptin on food intake and on anorectic effect of GLP-1 in Lou/C and Wistar rats. by Christelle Veyrat-Durebex (174178)

“…Values are mean <u>+</u> SEM of 8 rats per group. B and C) Percent decrease in food intake in Lou/C and Wistar rats, 2 and 4 hours after i.p. injection of leptin (0.5, 1 and 2 mg/kg, 19: 00). …”

Associations of alpha diversity measures and of major bacterial taxa and selected genera with levels of microbial enzymatic activity. by Roberto Flores (317863)

“…a<p>Log values of enzymatic activity IU/100 mg fecal protein. the two significantly associated principal components, per unit increase in alpha diversity, per tertile for Firmicutes and Bacteroidetes phyla, and per level (none, low, high) for the minor phyla, genera and unclassified bacteria.…”

Minimum concentration of Amphotericin B in serum according to the formulation, dose, and daily or prolonged intermittent therapeutic regimen by Leticia Aparecida Schiave (8438409)

“…The geometric mean Cmin tended to decrease with a reduction in the dose and frequency of intermittent L-AmB infusions: 357 ng/mL (100 mg 4 to 5 times/week) > 263 ng/mL (50 mg 4 to 5 times/week) > 227 ng/mL (50 mg 1 to 3 times/week). …”

Andro induced ROS-dependent autophagy while Taxi attenuated it. by Mazen Alzaharna (3737878)

“…<p>Cells were treated as indicated, stained with DCF-DA and then analyzed using the flow cytometer. (A) A representative histograms showing the increase in ROS in HeLa cells treated with Andro (25, 50 or 100 μM) while the decrease in ROS in those treated with Taxi (50, 100 or 200μM) for 24h. …”

Fig 4 - by Christian Mayr (12331709)

“…<p>(A) The effect of different ouabain concentrations on the cell membrane potential was evaluated over a time period of 90 minutes. 1 mM ouabain and 100 mM K⁺ were used as controls for membrane depolarization, 1 μM valinomycin was used as a control for membrane hyperpolarization. …”

miR-21 and <i>PDCD4</i> expression in HCA-7 cells treated with the COX-2 inhibitor NS398. by Oliver Peacock (643580)

“…<p>Following 72 hours treatment significant decrease in miR-21 levels is seen in NS398 treated cells (<b>A</b>). …”

Transcriptome-Wide Assessment of Human Brain and Lymphocyte Senescence by Mun-Gwan Hong (271202)

“…Few methodological approaches offer the means to explore this question on as broad a scale as gene expression profiling. …”

Increases in degenerating cortical neurons at 2 months followed by significant loss of cortical neurons and volume at 4 months in <i>Psen</i> cDKO mice. by Mary Wines-Samuelson (365524)

“…However, subsequent ages reveal a gradual decrease in cortical thickness in <i>Psen</i> cDKO mice. …”

Structural Stability and Flexibility Analysis of MEV, TLR2-MEV, and TLR4-MEV Systems During Molecular Dynamics Simulation. by Masoumeh Beig (19959198)

“…<p><b>(A)</b> Root Mean Square Deviation (RMSD) plots of the MEV, TLR2-MEV, and TLR4-MEV systems over 100 ns of molecular dynamics simulation, indicating the overall structural stability of the complexes. …”

Effect of CA-Inhibitors on sperm beat frequency and CA-activity. by Petra M. Wandernoth (149629)

“…In the presence of bicarbonate, the addition of 100 µM EZA decreases sperm beat frequency from 7.60±0.28 Hz to 4.26±0.21 Hz, whereas the addition of 100 µM AZA decreases beat frequency from 7.84±0.27 Hz to 5.13±0.31 Hz (<i>n</i> = 10). …”

<i>In vivo</i> Sema3C treatment prevents O₂-induced arrested vascular growth. by Arul Vadivel (424484)

“…Arrows highlight vWF-positive vessels; scale bars represent 100 µm. B. Mean data quantifying the number of vWF positive vessels between groups. …”

SPP and SKI-1 inhibitors block SARS-S- and MERS-S-driven entry. by Teresa Plegge (4164583)

“…Transduction measured in the presence of DMSO was set as 100%. Error bars indicate standard error of mean (SEM). …”

TCE treatment inhibits cell proliferation and induces process outgrowth. by Rachana Mishra (476515)

“…<p>(Table 1) Phytochemical analysis of TCE. (<b>A</b>) MTT assay showing dose dependent decrease in cell number in TCE treated U87MG, HeLa, PC3 and C6 cells. …”

Leptin-induced relaxation of phenylephrine-preconstricted mesenteric artery rings in different experimental groups. by Anna Jamroz-Wiśniewska (514346)

“…<p>NO-dependent vasorelaxation was measured in the presence of apamin (5 µM), TRAM-34 (1 µM) and indomethacin (10 µM), and EDHF-dependent vasorelaxation was examined in the presence of L-NAME (100 µM) plus indomethacin (10 µM). Maximal relaxation (R_max) was calculated as the leptin-induced percent decrease in tension developed in response to phenylephrine. …”

Change in mitochondrial transmembrane potential (ΔΨm) in different groups. by Ayyappan Prathapan (556848)

“…Decrease in JC-1 monomers and increase in JC-1 aggregates in BDE treated hypertrophied cells shows the capability of extract to protect mitochondria. …”

Sugar content variation in elephant grass germplasm by Thalita Bordignon da Cunha (12654240)

“…However, some accessions did have a significant increase or decrease in sugar content as they aged. …”

On membrane with high negative charge, only R154Q shows mild reduction in tubulation. by Tingting Wu (228837)

“…<p>A) Electron micrographs of liposomes (100% DOPS) tubulated by BIN1 N-BAR and mutants. …”

Inhibition of AADC by NSD-1015 in zebrafish. by De-Fen Shih (441898)

“…Compared to untreated fish, the inhibited larvae became shorter by gradient increase of NSD-1015 concentration. (<b>A</b>) The phenotype of treated larvae. From up to bottom is the untreated larvae (n=234), and treated larvae by inhibitor NSD-1015 100 µM(n= 312), 200 µM (n=300), 300 µM (n=304), 400 µM (n=264), and 500 µM (n=260). …”