Role of apoptosis-associated genes in transduced DU145 cells. by Nana Pei (504330)

“…<p>DU145 cells were transfected with TRAIL-R2,Gadd45a,TP53BP2 or HRK siRNA(20 nmol/L) or control siRNA (20 nmol/L) followed by transduction with Ad-G-AT2R-EGFP (100 ifu/cell) for 2 d. …”

BBB impairment seen as early as 3 days into cuprizone administration. by John Shelestak (8490477)

“…(D) Densitometry of western blot shows significant decrease in Occludin levels compared to controls. Data are expressed as a percentage of control with the highest control set at 100. …”

Identification of Key Genes. by Chen Wang (88408)

“…(D) Feature importance ranking in the RF model based on Mean Decrease Gini, highlighting the most influential genes. …”

Specificity of HUVECs intoxication by C2I using PA₆₃ in comparison to C2II. by Angelika Kronhardt (304086)

“…<p>HUVECs (5×10⁵ cells/100 mm well) were intoxicated with the indicated concentration of polypeptides during 48 (A) or 24 hours (B). …”

Effects of Aur treated or TrxR2 deficient N27 cells with 6OHDA. by Pamela Lopert (114596)

“…<p>(a) N27 cells were exposed to varying concentration of 6OHDA and Aur for 24 hr and cell death was measured via percent LDH released (n = 8−16). * = p<0.001 compared to 0 nM Aur with same 6OHDA concentration; # = p<0.001 compared to 100 nM Aur with same 6OHDA concentration determined by 2-way ANOVA. …”

M2 receptor expression in the postsynaptic membrane of C-boutons. by Léa Milan (786967)

“…<p>(<b>A)</b> Representative intensity plot profiles of CholineAcetylTransferase (ChAT, red channel and trace) and M2 receptor (green channel and trace) immunolabeling computed from the contour cutting of wild type (WT, left panels) and SOD1 (right panels) motoneurons of postnatal (P) 10 (<b>A1</b>) and P100 (<b>A2</b>) mice. …”

IRF1 suppresses the replication of HSV-1 partially by up-regulation of RSAD2. by Jing Ru (420034)

“…Viral yields were determined by standard plaque assays at 48 h post-infection with HSV-1. (E) Model of miR-23a regulation in HSV-1 replication. Increased levels of miR-23a in HeLa cells led to decrease levels of IRF1 mRNA and RSAD2 mRNA, with a consequent increase in HSV-1 replication. …”

Reptin depletion impairs H2AX phosphorylation at serine 139 (γH2AX) after DNA damage. by Anne-Aurélie Raymond (724178)

“…The graphs below show for each treatment the evolution of the number of foci per cell (left) or the fractional decrease of the number of foci, setting the initial time point as 100% (right).…”

FIGURE 2 from Surgical Inflammation Alters Immune Response to Intraoperative Photodynamic Therapy by Richard W. Davis (16964049)

“…The resulting curve demonstrated a transient decrease in tumor oxygenation 30 minutes after administration of TI which returned to a mean of 100% or 89.4% of the pre-TI level external to the incision and along the incision, respectively. …”

Strategies against gHAT in the Mandoul focus. by Marina Antillon (4439002)

“…The active screening algorithm specificity under <i>Mean AS & VC (a)</i> is 99.93% and for the strategies <i>Mean AS & VC (b)</i>, <i>Mean AS</i> and <i>Max AS</i> it is 100%. …”

Evolution of mutation rates on simple fitness landscapes with different ruggedness. by Jeff Clune (53764)

“…Although the optimal mutation rate increases as a function of valley size (note the right-shift in the dashed line from top to bottom), the evolved mutation rates in fact decrease as a function of valley size (note the left-shift of the blue and red points from top to bottom).…”

<i>In vitro</i> differentiation of <i>Mecp2</i> wild type ES cells is accompanied by large scale heterochromatin reorganization. by Bianca Bertulat (126768)

“…We noticed a highly significant (p<0.0001) decrease of mean chromocenter number per nucleus within the first two weeks of differentiation. …”

E4-ORF1 induces PBM-, PI3K-, and Dlg1-dependent cellular transformation. by Kathleen Kong (558240)

“…<p>(<b>A</b>) <i>Wt</i>ORF1 cells but not vector, V125A, or T123D cells grow in soft agar. …”

Two electrophysiological sleep states exist in the Argentine tegu. by Paul-Antoine Libourel (561599)

“…The vertical scale bars represent 100 μV. (B) Time frequency representation of 24 h of recording of a whitened LFP DVR split into four 6-h periods starting at 2 PM (in blue the low power, in red the high power). …”

SRRM4 expression inhibits cancer cell proliferation. by Sarah A. Head (6066398)

“…(F) Representative PCR showing the decreased WT/DM ratios of MDA-MB-231 cocultures over time. …”

Maternal β-catenin activity is hyperactivated in <i>nanog</i> mutant. by Mudan He (7017239)

“…<i>boz</i> was detected at 4 hpf, and <i>chd</i> was detected at 4.5 hpf. Scale bar, 100 μm. (D) Statistical analysis of the embryos in panel C. …”

MMP2 in stromal cell conditioned medium is important to drive PDAC cell invasion. by Hong Cao (122228)

“…MMP2 depletion in hPSC CM results in a >3-fold decrease in the percent of BxPC3 cells degrading the matrix (≥100 cells per condition, g) and a >8-fold decrease in the area degraded per cell in BxPC3 cells (≥10 cells per condition, h). …”

Transitions from Bursting to Single Spiking Output Are Mediated by Slow Recovery from Na⁺ Current Inactivation by Donald C Cooper (71501)

“…The inset shows a cumulative decrease in the action potential rise rate <i>(dV/dt)</i> (τ_1Hz = 17,980 ms, τ_2Hz = 925 ms, τ_10Hz = 250 ms; <i>n</i> = 14).…”

5OMV Inhibits HMGB1-Induced Tube Formation in HUVECs. by Wenyue Hou (10203722)

“…<p>Representative images <b>(A)</b> of the wound healing assay (captured at 0 h and 24 h post-scratching) demonstrated that co-treatment with 5OMV (100, 250, and 500 μg mL⁻¹) and HMGB1 (800 ng mL⁻¹) significantly attenuated HUVECs migration. …”

EWS/FLI-1 and R1507 influence the activation/expression of key molecules in the IGF-1 signaling pathway. by Helen J. Huang (201553)

“…An ELISA for IGF-BP3 was performed. Results show the mean and standard error of four experiments. Starting amounts of IGF-BP3 are higher than those in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0026060#pone-0026060-g002" target="_blank">Figure 2</a> because of the longer culture time required for transfection experiments. …”