Functional annotation of human missense SNVs. by Pete Heinzelman (7509374)

“…Roughly two-thirds display decreased spike binding, one-third display binding similar to wild-type ACE2, and a small fraction display increased binding. …”

PIAS1 inhibits the ability of TGFβto suppress E-cadherin promoter activity. by Stuart J. Netherton (152258)

“…Aii) Each column is the mean (± SEM, n = 5) of the percent repression of luciferase activity by TGFβ relative to that of the basal (− TGFβ) of the corresponding transfection as shown in Ai (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013971#s4" target="_blank">MATERIALS and METHODS</a>). …”

Results of MC simulations of VO and agonist infusion. by Johane H. Bracamonte (12883844)

“…<p>Top panels show normalized growth in CellArea for 100 representative simulations (gray lines), with terminal values indicated by black circles; adjacent boxplots reflect the mean, CI50, and CI90 of terminal values for 1000 simulations of a) Untreated VO, c) ISO infusion, and e) AngII infusion. …”

Let-7b targets at TLR4 and regulates TLR4 expression via post-transcriptional suppression. by Gui-gen Teng (380044)

“…A dose-dependent decrease of TLR4 protein was determined with let-7b mimics treatment. …”

Membrane localization of the C-terminal SipC actin-nucleation domain is required for synergy with SopB. by Robert J. Cain (272233)

“…Invasion rates after 60 min were compared to wild-type (assigned as 100%). Results are mean±SEM of 4 independent experiments each performed in triplicate. …”

The STD diet reduced the proportion of γδ T cells. by Julie Christine Antvorskov (329686)

“…(<b>F</b>) Percentages of CD8⁻CD103⁻ γδ T cells was lower in mice on the STD than on the GF diet, with a significant decrease in MLN and PLN. Barplots are mean values ± SEM of two independent experiments with 6 mice in each group. …”

The effect of hydroxychloroquine on lupus erythematosus-like skin lesions in MRL/lpr mice by Tatsuya Shimomatsu (1545943)

“…The average number of mast cells was 81, 50, and 12 (magnification, ×100), the mortality rate was 24%, 8%, and 9% and the mean body weight gain was 4.6 g, 8.0 g and 5.1 g, respectively.…”

Glycosaminoglycan (GAG) production from cultured chondrocytes under different oxidative conditions by Kazuo Yudoh (8787)

“…The HOtreated group exhibited a significant decrease in GAG production by chondrocytes as compared with the control group at all incubation times. …”

PFMA-3 induced glutathione and lipid peroxidation production greater than XRT. by Francesca Buontempo (3532004)

“…The regeneration currents recorded were reported as a percentage increase/decrease of the signal in respect to the one recorded at the same tip-dish distance but far away from cells (I_T/I_Tdish). …”

TBr inhibited cell proliferation in leukemia cell lines. by Anup S. Pathania (657368)

“…<p>(A–B) Cell proliferation assay. Cells were treated with 1, 10, 30, 50 and 100 µM concentrations of TBr for 24 and 48 h. …”

<i>Def6</i> morphants display defects associated with abnormal gastrulation movements. by Katerina Goudevenou (199855)

“…Two-tailed Student's <i>t</i>-tests showed a significant (p<0.001; three asterisks) decrease in length after injection of 2.5 ng <i>def6</i> MO versus wt embryos. …”

ErbB signaling is implicated in generation of neurons and mitoses in the sub-ventricular zone. by Tomomi Sato (301255)

“…Dotted circle, OT. Scale bar, 100 μm. <b>B</b>. Quantification of <i>pou4f1-hsp70l</i>:GFP intensity in the OT for the experiment shown in A (mean ± s.e.m.; **<i>P</i> < 0.01, ***<i>P</i> < 0.001; n = 8, 10, 16 for AG1478, AG43, DMSO, respectively). …”

Fetal survival after LPS administration. by Maide Ozen (6551636)

“…<p>(<b>A</b>) LPS at a dose of 90 ug/kg (LPS90) was administered i.p. to pregnant Wt or Het dams at E15.5 (control or Con, n = 9; LPS90, n = 8, sacrificed at E16.5). …”

DAAP1 depletion results in reduced attachment. by Melissa C. Steele-Ogus (12295373)

“…Unattached cells had a greater decrease in DAAP1 expression (38% ± 6) than attached cells (23% ± 2). …”

Soluble klotho blocks DAG stimulation of exocytotic insertion of pre-docked TRPC6 vesicles. by Jian Xie (629484)

“…<p>(A, B) Tetanus toxin (TTX) acts on synaptobrevin (“Sb2” for synaptobrevin-2) to decrease surface expression of TRPC6 channels. …”

Changes in the Bacterial Community Structure of Remediated Anthracene-Contaminated Soils by Laura Delgado-Balbuena (3211080)

“…On the one hand, application of earthworms removed most of the contaminant from the arable soil and had a strong effect on the bacterial community structure, i.e. a decrease in the relative abundance of the Acidobacteria, Chloroflexi and Gemmatimonadetes, and an increase in that of the Proteobacteria compared to the unamended soil. …”

Quantitative image analysis of ovaries from <i>mir-202 -/-</i> juvenile females. by Stéphanie Gay (5733569)

“…The number of small follicles (50–100 μm) is significantly higher compared to wild-type, while the number of follicles in the larger diameter class (200–350 μm) tends to decrease. …”

Caspase-8 activity modulation. by Eva Capdevila-Busquets (683895)

“…Overexpression of PSMC3IP or EPSTI1 in TRAIL-treated MDA-MB-231 <b>(A)</b> and MCF-7 cells <b>(B)</b> decrease caspase-8 activity based on the MYC-tag empty transfection vector (Vector) as control. …”

<i>Mecp2</i> deficient neurons and astroglia cells have significantly more chromocenters than wild type cells. by Bianca Bertulat (126768)

“…All analyzed samples show a highly significant (p<0.0001) difference of mean values. …”

Effect of CPP (Light) on GPDH activity in 3T3-L1 preadipocytes. by Kasumi Fujita (10271129)

“…<p>The activity of GPDH was calculated using the extinction coefficient of NADH, 6.22 mM^-1 cm^-1, and was calculated based on the decrease in NADH every 3 min. Enzyme activity is expressed as a value relative to the control (100%). …”