<i>In vivo</i> inhibition of ADAM15 activity reduces tumor growth. by Guadalupe Lorenzatti Hiles (2547727)

“…Subcutaneous inoculation of shA15UC6 cells (n = 10) in SCID mice led to decreased tumor weight compared to ctlA15UC6 control cells (n = 10) (<i>bottom</i>). …”

Data_Sheet_1_Coastal Flooding in the Balearic Islands During the Twenty-First Century Caused by Sea-Level Rise and Extreme Events.zip by Pau Luque (11248140)

“…We map projected flooded areas under two climate-change-driven mean sea-level rise scenarios (RCP4.5 and RCP8.5), together with the impact of an extreme event defined by the 100-year return level of joint storm surges and waves. …”

DataSheet_1_Safety, tolerability, pharmacokinetics and pharmacokinetic-pharmacodynamic modeling of cetagliptin in patients with type 2 diabetes mellitus.docx by Chen Zhou (466781)

“…Compared with placebo group, plasma active GLP-1 AUEC_0-24h increased by 2.20- and 3.36-fold in the 50 mg and 100 mg cetagliptin groups. A decrease of plasma glucose and increase of insulin and C-peptide were observed following OGTT in cetagliptin groups. …”

High oxygen concentration resulted in drastically reduced mRNA und protein expression of factors for neurodevelopment and plasticity, and DEX administration reversed these effects. by Stefanie Endesfelder (121559)

“…We detected in all plasticity factors a significant decrease under hyperoxic conditions for <b>A-E)</b> mRNA expression and <b>F-J)</b> protein expression. …”

Effect of high-voltage electrical stimulation and topical insulin on experimental cutaneous lesions by Rafaela Ferreira (3441404)

“…HVES was administered 24 hours after surgery, 30 minutes per day, with a frequency of 100 Hz and a mean voltage of 60 V, maintained at the motor threshold. …”

Defective TGF-β proliferative control in <i>Rb1^ΔL/ΔL</i> and <i>Rb1^ΔL/</i>⁺ mice. by Sarah M. Francis (355629)

“…Proportions were compared between genotypes using a chi-square test. Scale: 100 µm. † denotes previously published data that has been provided for comparison purposes.…”

Phenotypic changes following long term hypoxia selection. by Dan Zhou (29408)

“…A significant decrease at body weight was found in AF flies (lower panel, <i>p</i><0.01). …”

SopB inositol phosphatase activity is required for inhibition of <i>Salmonella</i> entry. by Robert J. Cain (272233)

“…Invasion rates after 60 min were compared to wild-type (assigned as 100%). Results are mean±SEM of 4 independent experiments each performed in triplicate. …”

Essential role of Sema4D in estrogen-mediated vaginal apoptosis. by Takuji Ito (566032)

“…OVX-oil treatment of WT mice significantly decreases apoptotic cell number in 5-week-old vaginal epithelia relative to that in Sham; compared with OVX-oil treatment, OVX-E2 treatment of WT mice induces a significant increase in apoptotic cell number in 5-week-old vaginal epithelia, comparable to the level of Sham. …”

Deletion of miR132/212 influences synaptic transmission and plasticity in the neocortex. by Judit Remenyi (178669)

“…Whole-cell recording were made at membrane potential of −80 mV in the presence of TTX (1 µM) and picrotoxin (100 µM). Scale bar measures 1 s and 10 pA. B) The superimposition of the average waveform (25 each) of mEPSCs recorded in the fl/fl neuron (black line) and miR-132/212 KO neuron (grey line) shown in A. …”

Immunnohistochemical analysis of CD200R expression in macrophages, the role of CD200-CD200R axis in hMSCs mediated immunosuppression. by Mika Pietilä (332438)

“…Only CD200Me 1, CD200Lo 2 and UCBMSC 2 lines had significant reduction in TNF-α secretion. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031671#s3" target="_blank">Results</a> are represented as a mean±SD of three independent replicates. …”

Turnover of 4MUG substrate reads out GBA1 activity in human brain lysates in the presence of sodium taurocholate. by Zdenek Berger (440685)

“…A representative experiment is shown in the graphs, a summary of three experiments is depicted in the table (mean ± SEM). …”

The effect of 5-LOX on TRPM7-mediated cell rounding and TRPM7 current density. by Hsiang-Chin Chen (247146)

“…The asterisk indicates a significant difference in cell rounding between 5-LOX knockdown (dsiLOX5-1 & dsiLOX5-2) and control cells (dsiCT), using Student's <i>t</i> test (<i>p</i><0.05) (D) Knockdown of 5-LOX did not appreciably decrease TRPM7's current density at +100 mV in 293-TRPM7 expressing cells transfected with dsiLOX5-2 compared to cells transfected with the control (dsiCT). …”

Relative Cx43 expression in C6 and F98 cells detected by western blot and RT- PCR analyses. by Zahra Moinfar (2504494)

“…<p>a) F98 cells showed a significant increase and b) C6 cells showed a significant decrease of Cx43 protein expression after treatment with 10 nM or 100 nM E2. c) Transfection of C6 cells with Cx43-cDNA neutralized these effects. d) RT-PCR showed an opposite effect of E2 on Cx43 gene expression in C6 when compared to F98 cells. e) A representative WB showing the increased Cx43 protein expression in F98 cells and the decreased Cx43 expression in C6 cells, after E2 treatment. …”

Ordered effector interplay revealed by <i>trans</i> BENEFIT screening. by Robert J. Cain (272233)

“…Invasion rates after 60 min were compared to wild-type (assigned as 100%). Results are mean±SEM of 4 independent experiments each performed in triplicate. …”

Data Sheet 1_Case Report: Micronized purified flavonoid fraction [Daflon]-induced bradycardia.pdf by Jhennyfer Aline Lima Rodrigues (10278251)

“…During this period, there was a decrease in vein inflammation and varicosity, as shown by magnetic resonance imaging.…”

Both caspase −3 and −9 inhibitors block apoptosis with mitochondrial dysfunction. by Junji Matsuo (187334)

“…*<i>p</i><0.05 vs. the absence of a caspase inhibitor (DMSO). B) A decrease of mitochondrial membrane integrity was observed in HEp-2 cells incubated with <i>Protochlamydia</i>. …”

52-Week Efficacy and Safety of Telbivudine with Conditional Tenofovir Intensification at Week 24 in HBeAg-Positive Chronic Hepatitis B by Teerha Piratvisuth (279131)

“…Myalgia was more common in the monotherapy group (19% versus 7%). No decrease in the mean glomerular filtration rate occurred in either treatment group at Week 52.…”

Late Mesozoic tectonic affinity of the Tengchong Block and southward extension of the Bangong-Nujiang Suture: constraints from Early Cretaceous granitic rocks in western Yunnan, SW... by Chen Wang (88408)

“…The Na-rich granodiorites have elevated Na₂O/K₂O ratios and Na₂O contents of 1.19–2.04 and 3.12–3.47 wt.%, respectively. These granodiorites also have relatively high Mg^# values and the transition metal element Cr of 53.3–54.5 and up to 100 ppm, respectively. …”

Insolubilization of HRD1 and SEL1L proteins by oxidative stress-inducing agents. by Ryo Saito (519632)

“…Data are normalized to the amount of β-actin; results are expressed as a fold increase compared with the non-treated control (mean ± SEM; <i>n</i> = 6). …”