Outbred HED-fed Sprague Dawley rats that defend elevated body weights have reduced melanocortin responses. by Dirk W. Luchtman (804535)

“…<p>(<b>A</b>) Weekly mean body weights of outbred Sprague Dawley rats fed HED or chow. …”

SipC-dependent relocalization of phosphatidylinositol-4,5-bisphosphate (PI₄₅P2) drives synergy with SopB. by Robert J. Cain (272233)

“…Invasion rates after 60 min were compared to wild-type (assigned as 100%). Results are mean±SEM of 4 independent experiments each performed in triplicate. …”

The effect on gliding responses of adding wings to looming discs with varying <i>l/|v|</i>. by Roger D. Santer (117354)

“…<p>A, Adding wings to looming discs caused a small, non-significant decrease in the relative frequency of glide occurrence across <i>l/|v|</i> values (see text). …”

OVA-specific cytokine production and proliferation of splenic lymphocytes. by Carolin Boehne (10531245)

“…<p>(A-C) Production of IL-5 (A), IL-10 (B) and IL-13 (C) in cell culture supernatants of spleens showed a significant decrease after tolerization compared to allergic (<i>OVA</i>) animals in both, WT and Tim-3^-/- mice. …”

Effect of palladin depletion on terminal differentiation of C2C12 cells. by Ngoc-Uyen-Nhi Nguyen (723223)

“…Note that palladin depletion resulted in a decrease of the fusion index at the late stage of differentiation. …”

Differing dissociation kinetics of oligonucleotides from TraI36 by Sarah L. Williams (13547)

“…All rights reserved</p> TraI36 was combined with 4 nM 5′-TAMRA-labeled WT 17-base ( and ), WT Hairpin () or G144′C Hairpin () oligonucleotide. …”

AMPA depotentiates synaptosomes. by Amadou T. Corera (372197)

“…<p>A, Synaptosomes were either left untreated (0 and 60 min. time points) or treated with AMPA (100 µM) for the indicated times. …”

Suppression of FcγRIa expression using shRNA prevents <i>E. coli</i> K1 entry into RAW 264.7 cells. by Rahul Mittal (202639)

“…Invasion experiments were performed in triplicate and were independently done three times. Data represent mean ± SD and the decrease in bound or intracellular bacteria was statistically significant when compared with control shRNA/RAW 264.7cells, *p<0.001 by Student's <i>t</i> test. …”

Determination of mitochondrial temperature in intact human cells. by Dominique Chrétien (217681)

“…The MTY fluorescence reached at the end of phase I was significantly different (<i>n</i> = 10; ***) from the starting value of 50%, whilst the final value in phase IV was not. (D) (a) Linear increase of fluorescence of HEK293 cells (preloaded for a minimum of 10 min, with 100 nM MTY), according to cell number (using cell protein concentration as surrogate parameter); (b) Maximal rate of decrease of MTY fluorescence (percentage, blue circles, corresponding with mitochondrial warming) is not significantly affected by cell number, whereas initial fluorescence increase in the presence of cyanide (percentage, green circles, corresponding with initial rate of mitochondrial cooling) is modulated by cell number (values at the three cell concentrations tested were significantly different from each other). …”

PKA-dependent stellation induces changes in phosphorylation of both profilins. by Stefanie K. Schweinhuber (687289)

“…Cultures treated with both FSK and KT attained a fraction of 0.22±0.02, which is a non-significant decrease (p = 0.11) compared to forskolin treated cultures. …”

<i>cd9b</i> mutant pairs lay smaller clutches of eggs with significantly fewer fertilised eggs. by Sarah Greaves (11772721)

“…This increase is apparent in (C), where the average breakdown of clutches from WT and <i>cd9b</i> mutant pairs is shown. The additional loss of <i>cd9a</i> in <i>cd9</i> dKOs did not result in a further decrease in the fertilisation rate (D). …”

Renal inflammatory cell infiltration in the obstructed kidney. by Alonso Narváez (6585305)

“…Both macrophages and T cells showed a decrease in infiltration after siRNA-CD40. ANOVA test; values are means ± SE, *p ≤ 0.05 vs D-UUO d2+Vehicle, ⁺p ≤ 0.05 vs D-UUO d2+siRNA SC.…”

Characterization of G6PI-induced arthritis by Robert Bockermann (12583)

“…DBA/1 mice were immunized intradermally at the base of the tail with the indicated amounts of G6PI emulsified in complete Freund's adjuvant (CFA) to establish a dynamic immunization protocol allowing for an increase or decrease in disease severity. …”

Training and Test Set Classification Accuracy for Naïve Bayes Method Using Motif Scores Only by Yuan Yuan (25702)

“…Including too many features will overfit the training set and thus decrease the test set accuracies. 100 random repeats of 5-fold CVs were performed, and the curves display the mean accuracies. …”

PrP^Sc accumulation in <i>TNFR1^−/−</i> lymph nodes requires LTβR signaling independent of <i>Prnp</i> expression. by Tracy O'Connor (143972)

“…Whereas TNFR1^−/−-Ig mLNs all harbored ≥6.1 log TCI units/g tissue, prion infectivity in TNFR1^−/−-LTβR-Ig mLNs was reduced by at least 2.5 log TCI units/g tissue. Total mRNA was isolated from spleens (J) or mesenteric lymph nodes (mLN; K) of mice from the indicated treatment groups and analyzed for Prnp expression by Real Time PCR (Mean ± S.E.M.: Spleen – WT-Ig = 100.69±6.74, WT-LTβR-Ig = 46.02±4.30, TNFR1^−/−-Ig = 48.94±0.55, and TNFR1^−/−-LTβR-Ig = 50.11±0.55; mLN – WT-Ig = 106.05±22.54, WT-LTβR-Ig = 101.69±12.88, TNFR1^−/−-Ig = 56.43±3.13, and TNFR1^−/−-LTβR-Ig = 72.35±6.65). …”

Pol II, nucleosome, and H3K4me3 dynamics at circadian promoters. by Pål O. Westermark (3140802)

“…NC = non-TATA box, CTF binding; NN = non-TATA box, non-CTF binding. Arrow highlights the striking high H3K4me3 signal continuing into the gene body.…”

Liver fibrosis in <i>CCL3^−/−</i> mice after eight weeks of MCD diet. by Daniel Heinrichs (323862)

“…Quantitative analysis of the Sirius red-positive area showed a significantly decrease in <i>CCL3^−/−</i> mice compared to wild-type mice (<b>B</b>). …”

K6 on Ub is required to direct lens denucleation. by Andrea Caceres (239354)

“…In addition, lenses that express K6W-Ub (panel 6) show decreased levels of phosphorylated lamin A/C (green) toward the lens core as compared to Wt (panel 5). …”

DataSheet_1_Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids.docx by Jacob MacWilliams (5040044)

“…This suggests that other cannabinoids and/or metabolites such as terpenes are causing the observed decrease in aphid performance in the whole plant assays. …”

Image_1_Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids.jpeg by Jacob MacWilliams (5040044)

“…This suggests that other cannabinoids and/or metabolites such as terpenes are causing the observed decrease in aphid performance in the whole plant assays. …”