PolyQ expansion affects p53-dependent apoptotic function in cells and in zebrafish. by Hongmei Liu (129385)

“…The ratio of embryos with the representative phenotypes was indicated. Both <i>WT</i> and <i>80Q</i> mRNA injections resulted in obvious <i>otx2</i> signal decreases in <i>p53 WT</i> but not <i>p53 mutant</i> zebrafishes, with more profound <i>otx2</i> signal reduction in <i>80Q</i> mRNA injections. …”

Inhibition of TOR signaling prevents meiotic onset in <i>Oikopleura dioica</i>. by Gunasekaran Subramaniam (546277)

“…There was a decrease in IdU incorporation in germline nuclei over time (D3–D18; day 3 to day 18). …”

Antibacterial activity of novel endodontic sealer. by Nurit Beyth (480476)

“…<p>Bacterial growth following direct contact with 4 weeks- aged RCS samples incorporating 0% or 1.5% (wt/wt) QPEI nanoparticles. Each point on the curve is the average absorbance (OD_650nm) measured simultaneously in eight wells similarly prepared in the same microtiter plate. …”

Plate 4 by Jenna Tomkinson (14757022)

“…</p> <p><br> There are 4 channels/stains:<br> - <strong>DAPI</strong> (DNA/Nuclei)<br> - <strong>GFP</strong> (ER)<br> - <strong>CY5</strong> (Mitochondria)<br> - <strong>RFP</strong> (Actin)<br> <br> There are NF1 Null and WT cells on this plate, with only the WT cells either not treated or treated with one of three siRNA constructs to decrease neurofibromin production using a dose curve.…”

Lithium treatment prevented neuronal loss in TG mice treated for 16 months in GrDG and increased the density of neurons in prefrontal cortex. by Marielza Andrade Nunes (830657)

“…<p>Brains sections were immunolabeled with NeuN antibody. TG Ctrl (n = 5) group had a decrease in proportional area stained compared to WT Ctrl (n = 4) (A). …”

Feijoa F3 does not activate autophagy or inhibit NF-κB activity in autophagy defective HCT116 cells. by Noha Ahmed Nasef (760610)

“…A percentage of greater than 100 shows increased inflammatory response in the presence of the ligand when compared to media (no treatment); and a percentage of less than 100 suggests a decrease in the inflammatory response in the presence of the ligand when compared to media (no treatment) meaning that a condition has inhibited NF-κB signaling. …”

Influence of the molybdenum content in cobalt and molybdenum catalysts supported on magnesium oxide for the production of carbon nanotubes by Thayana Goulart (10471918)

“…CoMo/MgO catalysts with low loading of cobalt, 5 wt.%, and three different loading of molybdenum, 5, 10 and 20 wt.%, were prepared by incipient wetness impregnation for high yield and pure carbon nanotubes. …”

The deamidation of N15 does not depend on deamidation of N71. by Ignacio de la Mora-de la Mora (435666)

“…<p>Native gel electrophoresis of the WT (A) or the N71D mutant (B) after incubation at 1mg/mL in TE buffer at 37°C with 3.5 mM GAP in a temporal course of 5 hours. …”

Dendritic spine analysis in Tg2576 mice and wildtype littermates. by Paul A. Adlard (31148)

“…<p>(A) Tg2576 animals have deficits in apical dendritic spine density at both four (n = 4) and fourteen (n = 5) months of age, as compared to WT mice (n = 4 at four months; n = 5 at fourteen months), that are reversed by short-term (11 days) PBT2-treatment (n = 3 at both age points). …”

Selective loss of macrophage subpopulations in lymphoid tissue of <i>Csf1rko</i> rats. by Dylan Carter-Cusack (20624041)

“…Positive logFC indicates an increase in expression in <i>Csf1rko</i> animals, while negative logFC indicates a decrease in expression in <i>Csf1rko</i> animals. …”

Effect of 3BrP on morphology, cell number, viability, proliferation and pluripotency. by Ana Sofia Rodrigues (491559)

“…Cells stained green were counted as live, while PI positive cells were counted as dead. 100 cells were counted per condition for a total of n = 8 independent experiments, results are expressed as means ± SEM for 30 experiments. …”

EFFECTS OF ADAPTED CANOEING ON THE CARDIOPULMONARY SYSTEM OF PARAPLEGICS by Elizângela Márcia de Carvalho Abreu (6147902)

“…The HF indices (un) and LF/HF showed no significant decrease of 5.7 and 7.0%, respectively. The highest breathing gains were for MVV (9.7%), MIP (8.5%) and MEP (11.0%), being however not significant. …”

Deletion of RBPJK enhances cell spontaneous differentiation in regular MSC culture. by Xifu Shang (784529)

“…<p>Mesenchymal stem cells were infected with Control shRNA(Co) or RBPJK shRNA (shRBPJK) lentivirus before being harvested for alkaline phosphatase (ALP) staining, western blot, RT-PCR analysis and BrdU ELISA. (A) Western Blot showed a significant decrease of RBPJK protein expression at day 3 and 14 following shRBPJK lentiviral infection. …”

Lack of PRLR impaired brown adipose tissue development in newborns. by Say Viengchareun (39121)

“…Results represent mean±SE. B, C and D) Decreased brown adipocyte size in BAT of PRLR KO (C) compared to WT mice (B). …”

Temperature Steps Induce Changes in <i>per4</i> Gene Transcription by Kajori Lahiri (230122)

“…</p> <p>(D and E) Cells transfected with the 0.4-kb WT and 0.4-kb Mut −7/−156/−173 constructs were subjected to the same rapid temperature decrease and increase, respectively, as described for (B) and (C).…”

<i>HAPX</i> overexpression affects the phase transition in <i>B</i>. <i>dermatitidis</i>. by Amber J. Marty (761758)

“…<b>(C)</b> Quantitative RT-PCR demonstrated a 3.4–5.8-fold decrease in <i>SREB</i> transcript abundance in OE strains #8 and #18 compared to WT and EV controls. …”

Myelin and myelin proteins are marginally reduced in the brain of <i>Syn1Cre; Galc flox/−</i>. by Conlan Kreher (13001753)

“…Scale bar = 100 μm. (<b>E</b>) Quantification of PLP level, measured by averaged integrated signal intensity, reveals a trend of reduction in the mutant brain. …”

Figure 4, supplementary figure 6 by Kristen Pleil (11084931)

“…</b>a) Proportion of responder categories during 10-minute E2 wash on across E2 doses (0.01, 1, 10, 100, 1000 nM) for frequency (top) and amplitude (bottom). b) Raw average frequency (top) and amplitude (bottom) during baseline, E2 wash on, and washout for each cell. c) Maximum % change from baseline for cells categorized as increased and decreased during E2 wash on for frequency (top) and amplitude (bottom). …”

Oligodendrocyte ablation affects synapse formation and remodeling at P1. by Sandrine Doretto (221560)

“…Insets (scale bar 12.5 µm) show NR1 localization on PC soma and dendrites in the WT whereas in MBP-TK mice NR1 staining appears internalized. …”

Diadinoxanthin (Ddx) concentration and de-epoxidation state (DES). by Benjamin Schellenberger Costa (461158)

“…O: no significant difference between WT and aureochrome 1a silenced strain; −: significant decrease in aureochrome 1a silenced strain compared to WT; +: significant increase in aureochrome 1a silenced strain compared to WT.…”