Innate anxiety-like behavior is increased in NPYGAD1-TG mice. by Katelynn M. Corder (5537507)

“…(<b>D</b>) Distance traveled in the central zone (as a percent of total) and (<b>E</b>) ambulatory time in the central zone (as a percent of total) were decreased in NPYGAD1-TG male and female mice compared to NPYGAD1-WT mice, with no sex-dependent difference. …”

All mutants exhibit sensitivity to prolonged Ca²⁺-chelation. by Stefanie Bunse (491659)

“…Error bars indicate SEM. n(WT) = 84, n(W2A) = 56, n(R14E) = 84, n(V81D/V174D) = 52 junctions. …”

Table_1_Use of Non-invasive Parameters and Machine-Learning Algorithms for Predicting Future Risk of Type 2 Diabetes: A Retrospective Cohort Study of Health Data From Kuwait.DOCX by Bassam Farran (553880)

“…We aimed to build prognostic models for the risk of T2DM in the Arab population using machine-learning algorithms vs. conventional logistic regression (LR) and simple non-invasive clinical markers over three different time scales (3, 5, and 7 years from the baseline).</p><p>Design: This retrospective cohort study used three models based on LR, k-nearest neighbours (k-NN), and support vector machines (SVM) with five-fold cross-validation. …”

Binding of the ficolins to different microorganisms. by Tina Hummelshøj (237744)

“…Strong interaction between the ficolins and microorganisms is indicated with values below 10%. OD450nm values at 100% for the ficolin-A, ficolin-2 and ficolin-3 assays were 2.039, 0.920 and 1.641, respectively. …”

SREBP-1 expression increases insulin signaling in primary hepatocytes. by Victoria Jideonwo (5172071)

“…<p><b>(A)</b> Mouse primary hepatocytes were cultured in DMEM containing 5 mM glucose, 10% FBS and 100 IU/ml penicillin/100 μg/ml streptomycin, 100 nM dexamethasone. …”

Pyrvinium inhibits WNT signaling in CRC cells. by Bin Li (39349)

“…Error bars indicate ± S.E.M of three experiments. *p<0.05. <b>C</b>. A nuclear or cytosolic fraction was extracted from vehicle or 100 nM Pyrvinium treated SW480 and HT29 cells and CTNNB1 protein levels were determined by immunoblot. …”

Mapping of accessible sites in the target mglB mRNA by RNase T1 and rEGS libraries. by Gaoping Xiao (210986)

“…The RNase P holoenzyme was reconstituted by 10 nM M1 RNA and 100 nM C5 protein. mglB mRNA cleavage products were separated on 8% polyacrylamide/7 M urea gels together with an alkali ladder and a partial RNase T1 digest of the same RNA. …”

DataSheet1_I-κB kinase-ε deficiency improves doxorubicin-induced dilated cardiomyopathy by inhibiting the NF-κB pathway.pdf by Yafeng Liu (192716)

“…In many cardiovascular diseases, I-κB kinase-ε (IKKε) has been recognized as a pro-inflammatory molecule. In this study, wild-type mice (WT, n = 14) and IKKε knockout mice (IKKε-KO, n = 14) were intraperitoneally injected with a cumulative dose of 25 mg/kg with Dox or Saline five times in 30 days. …”

Comparison of spatial resolution between SEM and IP-SEM. by Toshihiko Ogura (131016)

“…The resolution of SEM and IP-SEM system is almost same values. Scale bars: 100 μm in (A), 200 nm in (C).</p>…”

DataSheet_1_Microglia Susceptibility to Free Bilirubin Is Age-Dependent.docx by Ana Rita Vaz (6566963)

“…Remarkably, enhanced inflammatory-associated microRNAs (miR-155/miR-125b/miR-21/miR-146a) and reduced anti-inflammatory miR-124 were found in young microglia by both Bf concentrations, while remained unchanged (miR/21/miR-125b) or decreased (miR-155/miR-146a/miR-124) in aged cells. …”

Sirt1 expression, deletion, and testing FAA in mice lacking Sirt1 in Pomc neurons. by Dina R. Assali (5447489)

“…<p>Immunostaining for Sirt1 in the adult mouse brain reveals a broad neuronal expression pattern: (A) CA1 region of the hippocampus (scale bar indicates 100 microns) and (B) low magnification image of the dorsal hypothalamus (scale bar indicates 500 microns), showing robust Sirt1 expression in the paraventricular nucleus. …”

DataSheet_1_Tuning Scorpion Toxin Selectivity: Switching From KV1.1 to KV1.3.docx by Andrei M. Gigolaev (9090713)

“…Here we analyze MeKTx13-3 (Kalium ID: α-KTx 3.19) from the lesser Asian scorpion Mesobuthus eupeus, a high-affinity K_V1.1 blocker (IC₅₀ ~2 nM); it also affects K_V1.2 (IC₅₀ ~100 nM), 1.3 (~10 nM) and 1.6 (~60 nM). …”

Research design. by Marius Brazaitis (550027)

“…Cognitive function (CF) testing involved the unpredictable task switching test (executive function), the forward digit-span task test (short term memory), and the forced-choice recognition memory test (short term spatial recognition). Neuromuscular (NM) testing involved evaluation of spinal (H-reflexes, M-waves) and supraspinal (V-waves) excitability, evaluation of muscle contractility characteristics induced by a 1-s electrical stimulation at 1 Hz, 20 Hz, 100 Hz and TT-100 Hz; evaluation of maximal voluntary contraction torque and central activation of exercising muscle was performed with a TT-100 Hz superimposed stimulation on the maximal voluntary contraction. …”

Target species’ present day environmentally suitable space and predicted changes in short, medium, long term. by Rebecca Upson (3361301)

“…It is worth noting that % overlap in suitable environmental space would be 100% for the present day. For changes in environmentally suitable area available a value of < 100%, 100% or > 100% corresponds to a decrease, no alteration or increase.…”

Basic residue patches RRLRR and HRRRK are both required for membrane association of EHBP-1 NT-C2 domain. by Peixiang Wang (352425)

“…<b>(I)</b> Total area (per unit region) was quantified for GFP-labeled structures in <b>(A-F)</b>. Error bars are SEM (n = 18 each, 6 animals of each genotype sampled in three different regions of each intestine defined by a 100 x 100 (pixel²) box positioned at random). …”

Effects of etravirine on HIV-1 reverse transcriptase, recovered from plasma of HIV-1 infected patients. by Eva Agneskog (593818)

“…Based on the IC₅₀ value of BH10-wild-type (1.0±0.18 µM), which was included in every run, the IC₅₀ value and the fold-difference in susceptibility of each isolate were determined. A fold-difference of <5 was considered as sensitive, between 5–15 as decreased susceptibility, and above 15 as resistant.…”

Network connectivity, lateral inhibition, and decorrelation. by David E. Chen Kersen (11547607)

“…MC pairs were again partitioned based on inter-cell distance into 12 bins each representing a 100 <i>μ</i>m span. Each point represents the average decrease in firing rate of all MC pairs in a given bin and was placed halfway along the bin width, with the bar representing standard error. …”

Evaluation of anterior segment parameters using Scheimpflug technology during the Valsalva maneuver in patients with keratoconus by Yusuf Koçluk (5761517)

“…However, an increase in pupil diameter and a decrease in anterior chamber angle value were found. …”

Alpha activity induced by novel stimuli during REM sleep. by Perrine Ruby (486674)

“…Black dots on the topographies indicate electrodes showing a significant alpha increase or decrease compared to baseline.…”

Gonococci invasion of human macrophages is independent of CEACAM1. by Stanimir S. Ivanov (3394922)

“…The Internalization index for each condition was calculated by dividing the percentage of internalized objects from infections of the CEACAM1 KO U937 MFs cell line by the percentage of internalized objects from infections of the parental U937 MFs, which was then multiplied by 100. Values > 100% indicate increased object internalization by the KO cell line compared to WT cells, whereas values < 100% indicate decreased object internalization by the KO cell line. …”