Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor-2 by Kumar Shanmukhappa (66949)

Golgi staining and Sholl analysis of pyramidal neurons in CA1. by Juan Beauquis (359752)

“…(C) Quantification of the dendritic length of CA1 pyramidal neurons for the three distance ranges studied: 20–100 µm, 120–200 µm and 220–300 µm. Significant differences were found in the 20–100 µm range with a decrease in DIAB-SC mice (* <i>p</i><0.05 vs. …”

Acute Effects of Capsaicin on Energy Expenditure and Fat Oxidation in Negative Energy Balance by Pilou L. H. R. Janssens (429412)

“…Respiratory quotient (RQ) was more decreased at 75%CAPS (p = 0.04) than at 75%Control (p = 0.05) when compared with 100%Control. …”

Overexpression of <i>lprG-rv1410c</i> increases TAG released into culture medium of broth-cultured cells. by Amanda J. Martinot (398601)

“…Lower panel, OE vs. Mut2 total cells (12.5 μg lipid); 2-fold decrease, corrected p< 0.05 (blue), TAG (yellow overlay). …”

Harmonisation phase total power analysed locally by the partners. by Tim P. Ahuis (19964467)

“…Lab 2 and Lab 3 found a significant decrease in total power in Tg4510 mice compared to WT controls (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0309521#pone.0309521.s006" target="_blank">S6 Table</a>). …”

<i>Pten</i>^-/- HSCs are sensitive to DNA damage when mTOR activity is blocked with INK128. by Baoshan Xu (158726)

“…<i>Pten</i>^-/- HSCs exhibited a decrease in rDNA copy number compared to matched WT HSCs, samples were derived from three males of each genotype with 10 clones total, 3 from 2 mice and 4 from the third. …”

ASC-dependent inflammasomes promote leukocyte migration into the CNS during HSV-1 encephalitis. by Cooper K. Hayes (10063308)

“…After excluding multiplets, cell types were gated within the CD45^hi population using the following gating strategy: macrophages/monocytes Ly6G-/CD11c-/CD11b+, dendritic cells Ly6G-/CD11c+, neutrophils Ly6G+/CD11b+/CD11c-, T cells CD3+/CD4+ or CD3+/CD8+. No significant decrease was observed between WT and ASC^-/- mice for total CD45^hi, DCs, neutrophils, or T cells. …”

Depletion of METTL3 leads to slower proliferation in MEFs. by Hui Xian Poh (13118985)

“…We used a WB to confirm the loss of METTL3 using a second anti-METTL3 mAb. Five days after 4OHT treatment (500 nM), we observe loss of the WT METTL3 protein. 30 μg per lane. …”

Respiration of isolated mouse liver mitochondria. by Hamed Alborzinia (221077)

“…<p>Mitochondrial respiration consumes oxygen, depicted as a decrease of oxygen saturation over time. After about 50 min mitochondrial respiration buffer is exhausted, leading to continues reduction of mitochondrial respiratory activity. activity leads to a decrease in oxygen saturation, which decreases over time (control). …”

Treatment of ARDS tracheal aspirates with MMP-8 and MMP-9 inhibitors. by Michele Y. F. Kong (346852)

“…Incubation with 100 mcg/ml of doxycycline resulted in a 10% decrease in MMP-8 activity compared to basal levels (*<i>p = 0.05</i>). …”

Supplemental Figure 2 by Lipschutz (18506103)

“…B) Relative levels of citrate are shown for the MDCK cell<b> </b>lines (WT, Exoc5 KD, Exoc5 OE, and Exoc5 CTS-mut). Citrate is decreased in Exoc5<b> </b>KD and Exoc5 CTS-mut cell lines, and increased in Exoc5 OE, compared to WT cells. …”

Effect of EE housing on retinal synaptophysin- and Müller cell and astrocyte GFAP-immunoreactivity. by Damián Dorfman (293002)

“…Scale bar: 50 µm for panel A, B and C, and scale bar: 100 µm for panel D.</p>…”

<i>E</i>. <i>chaffeensis</i> TRP120 HECT E3 Ub ligase activity mediates K48 ubiquitination and degradation of FBW7. by Jennifer Y. Wang (8787527)

“…Densitometry values of FBW7 for each time point were denoted above respective bands (ctrl: 1.4 ±0.03; 24 hpt: 1.3±0.08; 48 hpt: 0.5±0.09), with Significantly (<i>p</i><0.05) decreased levels of FBW7 were detected at 48 hpt with TRP120 compared to control (n = 3). …”

Table_2_Dose of Alcohol From Beer Required for Acute Reduction in Arterial Stiffness.DOCX by Masato Nishiwaki (666290)

“…Arterial stiffness did not significantly change among all AFB and B25. However, B50, B100, and B200 caused a significant decrease in arterial stiffness for approximately 30–60 min: heart-brachial pulse wave velocity (B50: −4.5 ± 2.4%; B100: −3.4 ± 1.3%; B200: −8.1 ± 2.6%); brachial-ankle pulse wave velocity (B50: −0.6 ± 2.0%; B100: −3.3 ± 1.1%; B200: −9.3 ± 3.0%); heart-ankle pulse wave velocity (B50: −3.7 ± 0.3%; B100: −3.3 ± 0.9%; B200: −8.1 ± 2.7%); and cardio-ankle vascular index (B50: −4.6 ± 1.3%; B100: −5.6 ± 0.8%; B200: −10.3 ± 3.1%). …”

Table_1_Dose of Alcohol From Beer Required for Acute Reduction in Arterial Stiffness.DOCX by Masato Nishiwaki (666290)

“…Arterial stiffness did not significantly change among all AFB and B25. However, B50, B100, and B200 caused a significant decrease in arterial stiffness for approximately 30–60 min: heart-brachial pulse wave velocity (B50: −4.5 ± 2.4%; B100: −3.4 ± 1.3%; B200: −8.1 ± 2.6%); brachial-ankle pulse wave velocity (B50: −0.6 ± 2.0%; B100: −3.3 ± 1.1%; B200: −9.3 ± 3.0%); heart-ankle pulse wave velocity (B50: −3.7 ± 0.3%; B100: −3.3 ± 0.9%; B200: −8.1 ± 2.7%); and cardio-ankle vascular index (B50: −4.6 ± 1.3%; B100: −5.6 ± 0.8%; B200: −10.3 ± 3.1%). …”

Table_3_Dose of Alcohol From Beer Required for Acute Reduction in Arterial Stiffness.DOCX by Masato Nishiwaki (666290)

“…Arterial stiffness did not significantly change among all AFB and B25. However, B50, B100, and B200 caused a significant decrease in arterial stiffness for approximately 30–60 min: heart-brachial pulse wave velocity (B50: −4.5 ± 2.4%; B100: −3.4 ± 1.3%; B200: −8.1 ± 2.6%); brachial-ankle pulse wave velocity (B50: −0.6 ± 2.0%; B100: −3.3 ± 1.1%; B200: −9.3 ± 3.0%); heart-ankle pulse wave velocity (B50: −3.7 ± 0.3%; B100: −3.3 ± 0.9%; B200: −8.1 ± 2.7%); and cardio-ankle vascular index (B50: −4.6 ± 1.3%; B100: −5.6 ± 0.8%; B200: −10.3 ± 3.1%). …”

NK1R antagonist, aprepitant blocks SP-induced blebs, intracellular calcium increase and impedance changes. by John Meshki (36999)

“…<p>(<b>A</b>) Phase-contrast images of live U373MG cells preincubated with control or aprepitant (1 µM) for 10 min and then stimulated with SP (100 nM). …”

Elevations of HIF-1α mRNA and protein expressions by HMGB1 and their inhibition by cilostazol. by Hye Young Kim (135983)

“…(C) Time (3, 6, 12, and 24 hr)-dependent increases in HIF-1α protein levels in the presence of 100 ng/ml of HMGB1. (D) Concentration-dependent decrease of HMGB1 (100 ng/ml)-induced HIF-1α protein by cilostazol (CSZ; 1, 10 and 30 µM) and resveratrol (RES, 20 µM). …”

RAP host genes display intragenic termination. by Eva Klopf (3492986)

“…Both data sets, NET-Seq (B) and CRAC-Seq (D), show that RAP containing genes more often display a significant decrease downstream of the RAP compared to the randomized background.…”

Single Nucleotide Polymorphisms of Human STING Can Affect Innate Immune Response to Cyclic Dinucleotides by Guanghui Yi (201792)

“…The cyclic dinucleotides can be bacterial second messengers c-di-GMP and c-di-AMP, 3’5’-3’5’ cyclic GMP-AMP (3’3’ cGAMP) produced by <i>Vibrio cholerae</i> and metazoan second messenger 2’5’-3’5’ Cyclic GMP-AMP (2’3’ cGAMP). …”