Induced expression of <i>NBPF1</i> in human tumor cells impairs colony formation in soft agar. by Karl Vandepoele (74589)

“…Only colonies larger than 100 μm were counted. Induction of NBPF1 expression by adding Dox results in a severe decrease in the number of colonies in comparison to the control setting (Mock) or the non-induced (-Dox) cells.…”

cLTP-induced DA-actin exodus is blocked by an inhibitor of myosin II ATPase. by Toshiyuki Mizui (513144)

“…<p>Neurons (21 DIV) were preincubated with 100 µM (S)-(−)-blebbistatin (aBL, the active form of blebbistatin) for 30 min and then stimulated with cLTP solution for 3 min. …”

Cortical effects of STN-DBS stimulation with the patient at rest. by Mahdi Mahmoudzadeh (572024)

“…<p><b>(A)</b> EEG was band-pass filtered [100–200 Hz] and brain stimulation artifacts were marked in order to determine brain stimulation periods based on optical data. …”

Molecular Insight into the Slipperiness of Ice by Bart Weber (5226785)

“…Measurements of the friction coefficient of steel-on-ice over a large temperature range reveal very high friction at low temperatures (−100 °C) and a steep decrease in the friction coefficient with increasing temperature. …”

AMPK activators reduce DVL3 in cervical cancer cells. by H. T. Kwan (291038)

“…(D) Upon treatment of 1.25 μM A23187, the decrease of DVL3 could be observed after 10 and 12 hours in C33A and CaSki respectively, while a further 100% reduction of DVL3 was observed at 12 and 24 hours for both cell lines. …”

CTR1 silencing inhibits angiogenesis. by Gomathy Narayanan (456259)

“…C. Tube formation assay: a - Control, b- Cu 100 µM, c- Cu 100 µM+si 1 - 10 nM, d- Cu 100 µM+Ssi 10 nM, e- Cu 100 µM+P 800 µM. …”

Simulations of synaptic excitation and inhibition. by Stefano Masoli (9928807)

“…(B) PSTH of responses elicited by a short train (5 impulses @100 Hz) to 20 MF, 20 AA, and 89 PF synapses. …”

Population sorting II. by Xavier Manière (230820)

“…As expected, population with similar dynamics and intra population variability of velocities (larger µ) decrease the sorting efficiency. (C) Using the experimental data displayed on <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0016637#pone-0016637-g003" target="_blank">Fig. 3</a> we computed the distribution of worms position at time τ = 100s. …”

Effect of carboplatin treatment on the viability of breast cancer cell lines. by Khadidiatou Guiro (716667)

“…^b p<0.05, significant increase in non-viable BCCs at 50 μg/ml as compared to 0 μg/ml and 30 μg/ml. c) Carboplatin survival curve for chemotherapy treated and non-treated MDA-MB-231 cells, ^a p<0.05, significant decrease in percent viability (30%) of non-treated cells treated with carboplatin dosages between 100 μg/ml to 120 μg/ml as compared to treated cells (10%). …”

Image_4_Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.TIF by Amanda Q. Nguyen (8584413)

“…In contrast, ephrin-B1 OE in hippocampal astrocytes impaired dendritic spine formation and clustering, specifically on c-Fos(+) neurons, coinciding with an overall decrease in vGlut1/PSD95 co-localization. Although astrocytic ephrin-B1 influenced learning-induced spine formation, the changes in astrocytic ephrin-B1 levels did not affect spine enlargement as no genotype differences in spine volume were observed between trained WT, KO, and OE groups. …”

Data_Sheet_1_Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.docx by Amanda Q. Nguyen (8584413)

“…In contrast, ephrin-B1 OE in hippocampal astrocytes impaired dendritic spine formation and clustering, specifically on c-Fos(+) neurons, coinciding with an overall decrease in vGlut1/PSD95 co-localization. Although astrocytic ephrin-B1 influenced learning-induced spine formation, the changes in astrocytic ephrin-B1 levels did not affect spine enlargement as no genotype differences in spine volume were observed between trained WT, KO, and OE groups. …”

Image_3_Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.TIF by Amanda Q. Nguyen (8584413)

“…In contrast, ephrin-B1 OE in hippocampal astrocytes impaired dendritic spine formation and clustering, specifically on c-Fos(+) neurons, coinciding with an overall decrease in vGlut1/PSD95 co-localization. Although astrocytic ephrin-B1 influenced learning-induced spine formation, the changes in astrocytic ephrin-B1 levels did not affect spine enlargement as no genotype differences in spine volume were observed between trained WT, KO, and OE groups. …”

Image_1_Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.TIF by Amanda Q. Nguyen (8584413)

“…In contrast, ephrin-B1 OE in hippocampal astrocytes impaired dendritic spine formation and clustering, specifically on c-Fos(+) neurons, coinciding with an overall decrease in vGlut1/PSD95 co-localization. Although astrocytic ephrin-B1 influenced learning-induced spine formation, the changes in astrocytic ephrin-B1 levels did not affect spine enlargement as no genotype differences in spine volume were observed between trained WT, KO, and OE groups. …”

RhoGDI was involved in XIAP regulation of cell migration and actin polymerization. by Jinyi Liu (325830)

“…Stable transfectants of shRNA-RhoGDI in WT and XIAP^−/− cells were identified. …”

Image_2_Astrocytic Ephrin-B1 Controls Synapse Formation in the Hippocampus During Learning and Memory.TIF by Amanda Q. Nguyen (8584413)

“…In contrast, ephrin-B1 OE in hippocampal astrocytes impaired dendritic spine formation and clustering, specifically on c-Fos(+) neurons, coinciding with an overall decrease in vGlut1/PSD95 co-localization. Although astrocytic ephrin-B1 influenced learning-induced spine formation, the changes in astrocytic ephrin-B1 levels did not affect spine enlargement as no genotype differences in spine volume were observed between trained WT, KO, and OE groups. …”

Safe and effective subcutaneous adipolysis in minipigs by a collagenase derivative by Fuding Chen (8207553)

“…Three vectors were constructed for expressing rColH(FM, mutant for fat melting, with 6xHis tag), rColH(WT, wild-type, with 6xHis tag), and rColH(E451D, E451D mutant, without 6xHis tag) in <i>Escherichia coli</i>. rColH(FM) & rColH(WT) were purified by Ni Sepharose on a laboratory scale, while rColH(E451D) was purified by five chromatography purification steps on a large scale. …”

Down-regulation astrocyte-derived NT-3 <i>in vivo</i> reversed the trace fear memory of <i>Fmr1</i> KO mice. by Qi Yang (108283)

“…<i>n = </i>6 mice in WT and KO sham group, <i>n</i> = 5 in KO mice injected with negative shRNA infected WT astrocytes and si-508 shRNA infected KO astrocytes group. …”

Spontaneous EPSCs and IPSCs in wildtype and <i>orexin/ataxin-3</i> mice. by Natsuko Tsujino (169784)

“…Inset shows mean sEPSC amplitude of wildtype mice (WT) and <i>orexin/ataxin-3</i> mice (Tg). C. Cumulative probability plots of sIPSC inter-event intervals (n = 6–7), showing decrease in sIPSC frequency in <i>orexin/ataxin-3</i> mice. …”

Microelectrode simulation was performed to observe the recorded SPW-Rs in different regions of neural network. by Sadullah Canakci (4439137)

“…<b>(d)</b> SPW-R amplitude recording as a function of distance, revealing that LFP amplitudes show a decrease as a function of electrode distance to the network.…”

A genome-wide genetic screen identifies modifiers of LRRK2 toxicity in yeast. by Yulan Xiong (250746)

“…<p>(A) Yeast gene deletion strains <i>ahc2Δ</i> and <i>rmd8Δ</i> markedly enhance LRRK2-induced toxicity in yeast compared to the WT strain. Yeast WT strain BY4741 and gene deletion strains <i>ahc2Δ</i> and <i>rmd8Δ</i> cells were transformed with galactose-inducible expression constructs containing the central GTP-COR-Kin fragment of WT LRRK2 or empty vector as a control. …”