Atorvastatin preserved endothelial barrier integrity. by Hongbing Xiao (389238)

“…Thrombin treatment caused a dramatic decrease in resistance, reaching a maximum at 30 min (40%), reflecting decreased junction integrity. …”

Data_Sheet_1_Increasing Tau 4R Tau Levels Exacerbates Hippocampal Tau Hyperphosphorylation in the hTau Model of Tauopathy but Also Tau Dephosphorylation Following Acute Systemic In... by Matthew R. Barron (8533815)

“…Three-month-old male wild-type (Wt), mTau^+/−, mTau^−/−, hTau/mTau^+/−, and hTau/mTau^−/− mice were administered 100, 250, or 330 μg/kg of LPS or its vehicle phosphate buffer saline (PBS) [intravenously (i.v.), n = 8–9/group]. …”

Mutating key residues in HvHMA2 alters metal responses. by Rebecca F. Mills (121268)

“…<p>Mutation of predicted critical residues decreases the Cd sensitivity conferred by HvHMA2 on wt yeast (top) and the Zn resistance conferred on <i>zrc1cot1</i> mutant yeast (bottom). …”

NIH3T3 cells expressing Cx43dT-GFP show defects in wound closure and polarized cell movement. by Richard Francis (201117)

“…This was associated with a significant decrease in both the directionality and speed of wound closure (H). …”

Bifurcation analysis to explore menses-associated parameter alterations. by Christina Y. Lee (12116748)

“…For example, the origin (0,0) indicates the baseline values for each sample and (-1,0.5) would indicate a 100% decrease in α_{oLB →nAB and} α_{Li →nAB} and a 50% increase in k_grow-Li and k_grow-oLB. …”

Blocking the C/EBPβ-Thr217 phosphorylation ameliorates the induction of lung fibrosis by Bleomycin. by Martina Buck (82941)

“…After Bleomycin treatment, C/EBPβ^wt mice had moderate to severe lung fibrosis compared to controls, while C/EBPβ-Ala217 mice of the same genetic background had mild or moderate lung fibrosis (mean scores : 2.8+/−0.4 vs. 1.5+/−0.5; <i>n</i>: 10 per group; <i>P</i><0.001). …”

Positive feedback in SIC1 degradation and CLB2 activation. by Debashis Barik (3389255)

“…</b> The durations of SG2M phase (<i>T</i>_sg2m = <i>T</i>_div−<i>T</i>_g1) from single-cycle simulations of an extant population of daughter and mother cells are plotted for WT cells, WT cells with decreased rate constant for the phosphorylation of Fkh2 by Clb2 (i.e., decreasing strength of the positive feedback for <i>CLB2</i> activation), and WT cells with the weakest positive feedback loop and increased rate constants for phosphorylation of Fkh2 by Cln1,2,3 and Clb5. …”

Inhibition of KDM expression <i>in vivo</i>. by Hanitriniaina Rabeony (596171)

“…Skin sections were stained with Hematoxylin and immunodetection of cytokeratin 10, loricrin, filaggrin, involucrin and S100A7 was performed. Scale bar 100 µm. Results are from one experiment representative of three.…”

Supplementary Material for: Global, regional, and national epidemiology of Idiopathic Childhood Epilepsy from 1990 to 2021 by figshare admin karger (2628495)

“…Results: In 2021, there were approximately 1.23 million cases of childhood epilepsy worldwide, marking a 26.34% increase from 1990. During the same period, deaths attributed to epilepsy decreased from 25,768 to 18,171. …”

Induction of VE-cadherin proteolytic cleavage by <i>P. aeruginosa</i> T2SS. by Guillaume Golovkine (534765)

“…(B) Confluent HUVECs were infected for 4.5 h with PAO1 (WT), PAO1Δ<i>3Tox</i> (Δ3T), or PAO1Δ<i>pscD</i> (Δ<i>pscD</i>) at MOI = 10. …”

<i>Per1</i> plays a more important role than <i>Per2</i> and <i>Per3</i> in sustaining retinal and SCN molecular rhythms and the <i>Period</i> genes have divergent effects on retin... by Guo-Xiang Ruan (159038)

“…<p>(<b><i>A</i></b><b>–</b><b><i>L</i></b>) Representative PER2::LUC or <i>Per1::luc</i> bioluminescence traces recorded from WT and <i>Per1</i>−/−, <i>Per2</i>−/− and <i>Per3</i>−/− retinal and SCN explants. …”

G- and F-Actin in RP1-expressing cells. by Frank Stenner (24360)

“…The bottom panels show the respective degree of G-actin decrease seen in the RP1-wt, ALA, ASP containing cell lines. …”

Combination therapy restores wound neovascularization partially though PC-mediated vasculogenesis. by Robert J. Allen Jr. (540312)

“…<b>C</b>) BrdU-labeling of PCs in the presence of AMD3100 demonstrates only minor, non-significant, inhibition in PC proliferation (15.4±3.3% decrease, p = 0.06). <b>D</b>) When 2.5×10⁴ DiI-labeled PCs were intravascularly delivered to wounded animals on post-wounding day 1 and wounds were then harvested on post-wounding day 28 after lectin perfusion, we observe direct incorporation of PCs (red) into wound neovasculature (green) with DAPI counterstain (blue). …”

Denaturant-dependent refolding and unfolding kinetics of CcdB mutant proteins (related to Fig 2). by Gopinath Chattopadhyay (9365504)

“…<p>(A-E) Representative refolding rate constants of fast phase (left side) and slow phase (right panel) and (F-H) unfolding rate constants at 5 μM protein concentration of the WT and mutants are shown. …”

There is a non-linear relationship between <i>FOXO</i> expression and nutritional plasticity. by Hui Yuan Tang (196925)

“…Circles indicate flies in which we have manipulated <i>FOXO</i> expression using UAS-GAL4, diamonds indicate wild-type flies reared at different temperatures (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002373#pgen.1002373.s005" target="_blank">Figure S5</a>). (B) The nutritional static allometry of wings with different levels of <i>FOXO</i> expression shows that at very high levels of <i>FOXO</i> expression (><i>FOXO.wt</i> at 25°C), wing size is small even in well-fed flies with large bodies, while at very low levels of <i>FOXO</i> expression (<i>>FOXO.RNAi</i> at 20°C) wing size is large even in poorly-fed flies with small bodies. …”

DEGs in splenic networks. by Nupur Dasgupta (180790)

“…<p>The networks were generated using IPA software and were from the direct comparisons of imig- vs. vela-treated data sets without normalization to WT. The pathway included DEGs with decreased expression (imig/vela, green symbols) and the DEGs with expression level-increased (imig/vela, red symbols). …”

Hydrogen Sensors Based on Flexible Carbon Nanotube-Palladium Composite Sheets Integrated with Ripstop Fabric by Colin McConnell (8170839)

“…The amount of palladium in the composite was 16.5 wt % as measured via thermogravimetric analysis. …”

Model of the <i>D</i>. <i>discoideum</i> autophagic response during <i>M</i>. <i>marinum</i> infection. by Elena Cardenal-Muñoz (341021)

“…Downregulation of TORC1, which is always bound to the wt MCV membrane, induces the formation of autophagosomes that somehow repair the membrane damages and provide the MCV with cytoplasmic material. …”

Effects of PACAPs and/or oxidative stress on NFAT4, calcineurin expression and activity in chondrifying cells. by Tamás Juhász (195396)

“…<p>PACAP 1-38 at 100 nM, PACAP 6-38 at 10 µM were applied continuously from day 1. …”

Correlation of Cervical Cancer Mortality with Fertility, Access to Health Care and Socioeconomic Indicators by Diama Bhadra Vale (6879314)

“…In the multivariate analysis, only fertility rate was significantly associated with the CC mortality rate (coefficient of correlation: 9.38; 95% confidence interval [CI]: 5.16-13.59). Conclusion A decrease in the fertility rate, as expected when the level of development of the regions increases, is related to a decrease in the mortality rate of CC. …”