image1_Improved Survival and Retinal Function of Aging ZDF Rats in Long-Term, Uncontrolled Diabetes by BGP-15 Treatment.tif by Zita Wachal (10657409)

“…During the 12 months of treatment, 100% of BGP-treated animals survived compared to the non-treated ZDF group, where 60% of the animals died, which was a statistically significant difference. …”

image2_Improved Survival and Retinal Function of Aging ZDF Rats in Long-Term, Uncontrolled Diabetes by BGP-15 Treatment.tif by Zita Wachal (10657409)

“…During the 12 months of treatment, 100% of BGP-treated animals survived compared to the non-treated ZDF group, where 60% of the animals died, which was a statistically significant difference. …”

Circadian expression profiles of 14 tissue-specific TFs. by Ying Li (38224)

“…<p>The expression levels of <i>bhlhe40</i>/<i>41</i> and <i>per3</i> together with 11 circadian tissue-specific TFs were measured by real-time PCR in 5 dpf <i>clock</i> morphants (red) compared to WT (blue) or control (green) morphants. …”

The Core Set of C. albicans Caspofungin-Responsive Genes by Vincent M Bruno (61844)

“…“Gene symbol” refers to entries in CGD. The columns “wt−/wt+,” “<i>ada2</i>/wt+,” “<i>cas5</i>/wt+,” and “<i>rlm1</i>/wt+” summarize the response of each gene in microarray comparisons of the untreated wild-type strain, the treated Ca<i>ada2</i>Δ/Δ strain, the treated Ca<i>cas5</i>Δ/Δ strain, and the treated Ca<i>rlm1</i>Δ/Δ strain, each compared to the treated wild-type strain, respectively. …”

Clathrin-dependent endocytosis from the cell surface through the early and late endosome positively regulate Robo signaling <i>in vitro</i>. by Rebecca K. Chance (2207449)

“…(I, J) Inhibiting entry into the early (I’), or late (J’) endosome by co-expression of DN-Rab5, or DN-Rab7, respectively, with WT Robo causes a decrease in total process area, and a downward shift in the Sholl profile (K: Rab5DN n = 14, Rab7DN n = 13). …”

Acute stimulation of Type III Nrg1 signaling in Type III Nrg1^+/− sensory axons does not rescue functional TRPV1 deficits. by Sarah E. Canetta (46254)

“…The maximum percent change in intracellular calcium ([(F−F₀)/F₀]*100) in response to capsaicin decreased between the 4^th and 5^th capsaicin application in Type III Nrg1^+/− axons under control conditions (left) and did not increase when Type III Nrg1 signaling was stimulated by sErbB4-ECD application during that interval (right). …”

Evaluation of Multidimensional Chromatography Coupled with Tandem Mass Spectrometry (LC/LC−MS/MS) for Large-Scale Protein Analysis:  The Yeast Proteome by Junmin Peng (156839)

“…We present a comparison of this experiment with a previously published yeast proteome analysis by Yates and colleagues (Washburn, M. …”

Log2 ratios from simulated exemplar tumors at varying purity levels. by Soroush Samadian (5028617)

“…The purity value for each tumor type (in gray), is the median purity value for each cancer type according to TCGA segments. As the purity decreases, we observed a corresponding decrease in log2ratios of tumor segments (reduction in color intensities). …”

Exposure to particle debris generated from passenger and truck tires induces different genotoxicity and inflammatory responses in the RAW 264.7 cell line by Anna Poma (835467)

“…In MTS assay, after 24 hours, it was found that PP induced a 30% decrease in metabolic activity at a concentration of 10 μg/ml, while TP caused reductions of 20% and 10% at concentrations of 10 μg/ml and 50 μg/ml, respectively. …”

Data_Sheet_1_Girls-Boys: An Investigation of Gender Differences in the Behavioral and Neural Mechanisms of Trust and Reciprocity in Adolescence.pdf by Imke L. J. Lemmers-Jansen (6328598)

“…</p>Methods<p>Here we investigate age-related gender differences in trust and reciprocity (n = 100, 51 female) and associated neural mechanisms (n = 44, 20 female) in adolescents between 13 and 19 years of age. …”

Protein expression in ramp GCN mutants. by William A. Barr (9396098)

“…The right column indicates the increase or decrease compared to WT in the frequency of G1 and C2 in codons 3 through 8. …”

Data_Sheet_2_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…The long-term effects on cognitive processes and hyperactivity from sugar overconsumption, beginning at adolescence are not known. Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …”

Data_Sheet_2_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…The long-term effects on cognitive processes and hyperactivity from sugar overconsumption, beginning at adolescence are not known. Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …”

Image_1_Carbon monoxide promotes stomatal initiation by regulating the expression of two EPF genes in Arabidopsis cotyledons.jpeg by Xianjie Weng (14103780)

“…Consistent with this result, mutation of the CO biosynthesis gene HY1 resulted in a decrease of SI in hy1-100 plants, while overexpression of HY1 led to an increase of SI. …”

Image_2_Carbon monoxide promotes stomatal initiation by regulating the expression of two EPF genes in Arabidopsis cotyledons.jpeg by Xianjie Weng (14103780)

“…Consistent with this result, mutation of the CO biosynthesis gene HY1 resulted in a decrease of SI in hy1-100 plants, while overexpression of HY1 led to an increase of SI. …”

Structure Based <i>In Silico</i> Analysis of Quinolone Resistance in Clinical Isolates of <i>Salmonella</i> Typhi from India by Manoj Kumar (205700)

“…The present study assists in understanding the underlying molecular and structural mechanism for decreased fluoroquinolone susceptibility in clinical isolates as a consequence of mutations in DNA Gyrase.…”

Data_Sheet_1_Long-Term Overconsumption of Sugar Starting at Adolescence Produces Persistent Hyperactivity and Neurocognitive Deficits in Adulthood.PDF by Kate Beecher (6688340)

“…The long-term effects on cognitive processes and hyperactivity from sugar overconsumption, beginning at adolescence are not known. Using a well-validated mouse model of sugar consumption, we found that long-term sugar consumption, at a level that significantly augments weight gain, elicits an abnormal hyperlocomotor response to novelty and alters both episodic and spatial memory. …”

Whole Genome Sequencing to Investigate the Emergence of Clonal Complex 23 <em>Neisseria meningitidis</em> Serogroup Y Disease in the United States by Mary G. Krauland (157219)

“…This increase was accompanied by antigenic shift of three outer membrane proteins, with a decrease in the population that predominated in the early 1990s as a different population emerged later in that decade. …”

IL-1β, IL-6, and RANTES as Biomarkers of Chikungunya Severity by Lisa F. P. Ng (252501)

“…Statistical analysis showed that an increase in IL-1β, IL-6 and a decrease in RANTES were associated with disease severity.…”

Table_1_Carbon monoxide promotes stomatal initiation by regulating the expression of two EPF genes in Arabidopsis cotyledons.docx by Xianjie Weng (14103780)

“…Consistent with this result, mutation of the CO biosynthesis gene HY1 resulted in a decrease of SI in hy1-100 plants, while overexpression of HY1 led to an increase of SI. …”