Is Obstructive Sleep Apnea Associated with Cardiovascular and All-Cause Mortality? by Xiahui Ge (437665)

“…<div><p>Background</p><p>Studies have reported inconsistent findings regarding the association between obstructive sleep apnea (OSA) and future risks of cardiovascular and all-cause mortality. We conducted a meta-analysis to investigate whether OSA is an independent predictor for future cardiovascular and all-cause mortality using prospective observational studies.…”

Epigenetic Regulatory Effect of Exercise on Glutathione Peroxidase 1 Expression in the Skeletal Muscle of Severely Dyslipidemic Mice by Albert Nguyen (2580886)

“…Of these genes, only <i>Gpx1</i> exhibited changes in DNA methylation associated with dyslipidemia and exercise: we observed both increased DNA methylation with dyslipidemia and a transient decrease in DNA methylation with exercise. …”

CaMKII selective peptide inhibitors reduces myocardial fibrosis in SHRs. by Ersilia Cipolletta (760356)

“…SHR treated with AntCaNtide and tat-CN17β showed a decrease of interstitial fibrosis and reduced cardiomyocytes size when compared to SHR untreated group. …”

Synthetic Multivalent Antifungal Peptides Effective against Fungi by Rajamani Lakshminarayanan (321411)

“…Replacing the first arginine led to a 2–4 fold decrease in antifungal activities and reduced membrane disruption properties. …”

LPS triggered chemotactic signaling through fAR1. by Miao Pan (5285834)

“…A Student <i>t</i> test indicated a statistically significant difference in LPS binding between <i>far1</i>^<i>−</i> and <i>WT</i> cells (* indicates <i>P</i> < 0.01). …”

30 Hz stimulation does not permit recovery from previous ensemble recall. by Casey M. Baker (16033144)

“…<p>(A) We categorized the 8 stimulations for each stimulation period as either odd or even stimulations. …”

Data_Sheet_1_The Sensitivity of Subsurface Microbes to Ocean Warming Accentuates Future Declines in Particulate Carbon Export.pdf by Emma Louise Cavan (6178583)

“…In line with observations from polar regions and the deep ocean we imposed an elevated temperature sensitivity (E_a = 1.0 eV) to cooler regions; firstly to the Southern Ocean (south of 40°S) and secondly where temperature at 100 m depth <13°C. …”

Optimizing light-cured composite through variations in camphorquinone and butylhydroxytoluene concentrations by Hani NASSAR (12805999)

“…Sixteen groups of resin composite were prepared using combinations of four CQ (0.1%, 0.5%, 1.0%, and 1.5%) and four BHT (0.0%, 0.5%, 1.0%, and 1.5%) concentrations. …”

Loss of Slfn3 induces a gender-dependent repair vulnerability after 50% bowel resection by Emilie DeKrey (9389738)

“…Mitotic marker, Phh3+, and proliferation marker expression of Lgr5, FoxL1, and PDGFRα were increased after resection in male WT but this effect was blunted in male Slfn3KO mice. …”

Effect of inhibitors of p38 MAPK or PKC on stimulated shedding by ADAM17T735A and ADAM17ΔC. by Katherine C. Hall (180988)

“…C) <i>Adam17−/−</i> mEFs transfected with TGFα together with WT ADAM17 were stimulated with 5 ng/ml IL-1β, 1 µM anisomycin or 25 ng/ml PMA in the presence or absence of 4 µM BIM I. …”

Myelin alteration in 8-week-old TRAF4-KO mice. by Sébastien Blaise (332585)

“…(C): Western blot analysis of the myelin-specific MBP marker and of the interglial-specific TJ marker claudin 11 (cl 11) showed a decreased expression level of both proteins in 4 independent TRAF4-KO cerebellum protein extracts (lanes 5–8) compared with 4 WT samples (lanes 1–4) ; tubulin served as a loading control. …”

Role of voice therapy in adherence to voice rest (King et al., 2021) by Renee E. King (11409101)

“…</div><div><b>Results:</b> Talking decreased postprocedure by 63% in the therapy group and 65% in the counseling group, both significantly more than the 35% decrease measured in the evaluation group. …”

Supplemental data of the manuscript “Accumulation of seminolipid in Sertoli cells is associated with increased levels of reactive oxygen species and male subfertility: Studies in a... by Kessiri Kongmanas (7467368)

“…</p> <p><b>Supplemental Figure S7</b> Levels superoxide anions (2HE) and other ROS + oxidants (Eth) of the cauda epididymis of 5-month-old <i>Arsa^-/-</i> mice and WT mice<b> (A)</b> and of the caput epididymis of 5-month-old and 8-month-old <i>Arsa^-/-</i> mice and age-matched WT mice <b>(B)</b>. …”

Expression of two <i>tenascin</i> genes is affected by temperature. by Che-Yi Lin (218292)

“…<p><i>In situ</i> hybridization against <i>tenascin-c</i> (<i>tnc</i>) (A-H) and <i>tenascin-w</i> (<i>tnw</i>) (L-O) in 22-ss wild-type (WT) and <i>s1pr2^as10</i> (<i>as10</i>) mutant embryos raised at 28.5°C or 22.5°C. …”

Rac2 promotes differentiation of M2 macrophages <i>in vitro</i>. by Shweta Joshi (555748)

“…(D) & (E), Heatmap representation of metabolites across BMDMs from WT (n = 5) and Rac2-/- (n = 5) mice. Shades of yellow represent elevation of a metabolite and shades of blue represent decrease of a metabolite relative to the median metabolite levels (see color scale). …”

SLS-4 is required for the <i>in vitro</i> ubiquitination of poly-SUMO-2 chains and degradation of SUMO conjugates <i>in vivo</i>. by Chris Boutell (205885)

“…<p>(A) <i>In vitro</i> ubiquitination reactions were carried out in the presence of E1, UbcH5a and ubiquitin (Ubmix), poly-SUMO-2 chains and purified wt ICP0, ICP0ΔRING, or ICP0 C-terminal truncation mutants ICP01-323, ICP01-396 or ICP01-396mSLS-4 as indicated (-/+). …”

Table_1.pdf by Hena Ahmad (4995290)

“…Both, western blot and confocal microscopy confirmed an increase of ataxin-2 in BE(2)-M17 cells transduced with lentivirus expressing mt-ELF2 (CEE-mt-ELF2), which was not observed in cells transduced with lentivirus expressing wt-ELF2 (CEE-wt-ELF2). Moreover, we observed a significant decrease in the number and size of lipid droplets in the CEE-mt-ELF2-transduced BE (2)-M17 cells, but not in the CEE-wt-ELF2-transduced BE (2)-M17. …”

Image_1.pdf by Hena Ahmad (4995290)

“…Both, western blot and confocal microscopy confirmed an increase of ataxin-2 in BE(2)-M17 cells transduced with lentivirus expressing mt-ELF2 (CEE-mt-ELF2), which was not observed in cells transduced with lentivirus expressing wt-ELF2 (CEE-wt-ELF2). Moreover, we observed a significant decrease in the number and size of lipid droplets in the CEE-mt-ELF2-transduced BE (2)-M17 cells, but not in the CEE-wt-ELF2-transduced BE (2)-M17. …”

<i>Mmp13</i>^−/− mice display increased bone volume during non-stabilized fracture healing. by Danielle J. Behonick (81485)

“…Scale bar = 1 mm (B) Histomorphometric measurements of total bone volume (BV) and total bone volume as a proportion of total callus volume (BV/TV) in WT and <i>Mmp13</i>^−/− mice at days 7 (WT <i>n</i> = 6, <i>Mmp13</i>^−/−<i>n</i> = 6), 10 (WT <i>n</i> = 8, <i>Mmp13</i>^−/−<i>n</i> = 6), 14 (WT <i>n</i> = 8, <i>Mmp13</i>^−/−<i>n</i> = 6), 21 (WT <i>n</i> = 6, <i>Mmp13</i>^−/−<i>n</i> = 6), 28 (WT <i>n</i> = 6, <i>Mmp13</i>^−/−<i>n</i> = 6) and 56 (WT <i>n</i> = 5, <i>Mmp13</i>^−/−<i>n</i> = 4) confirm this observation There is a statistically significant decrease in BV in <i>Mmp13</i>^−/− calluses compared with WT at day 7 (*p<0.05), but a statistically significant increase in BV and BV/TV in <i>Mmp13</i>^−/− calluses compared with WT at days 28 (**p<0.01 and p<0.05 respectively) and 56 (*p<0.05). …”

Search results of kinetic parameter space and prediction of MdmX effect. by Sohyoung Kim (253617)

“…</p>c<p>The presence of MdmX (upto 100 fold k15) decreased maximum value (peak of oscillations) by >30%.…”