Effects of <i>tel1Δ rad3Δ</i> mutations on recruitment of telomere capping complexes. by Bettina A. Moser (260302)

“…Compared to wt cells, only <i>tel1Δ rad3Δ</i> (P = 0.006) had a significant decrease in Tpz1 binding, while decreases in <i>tel1Δ</i> (P = 0.108) and <i>rad3Δ</i> (P = 0.170) were not significant. …”

The hydration and alteration of perlite and rhyolite by J.S. Denton (2846327)

Siah1/2-dependent gene expression analysis confirms an ER stress signature. by Marzia Scortegagna (561529)

“…Panel c shows genes from pairwise comparisons: ko versus wt, koTG versus wtTG and koTM versus wtTM. (D) Principal component analysis (PCA) 3D plot for the microarray data set. …”

Supplementary Material for: Urine Osmolality and Renal Outcome in Patients with Chronic Kidney Disease: Results from the KNOW-CKD by Lee M.J. (4145941)

“…This association was particularly evident in patients with CKD stages 3–4 (per 10 mosm/kg decrease; HR, 1.02; 95% CI, 1.00–1.03). Adding urine osmolality to a base model with conventional factors significantly increased the ability to predict CKD progression (C-statistics, 0.86; integrated discrimination improvement [IDI], 0.021; both <i>p</i> < 0.001). …”

Effect of treatment of mature biofilms with tobramycin (A) or meropenem (B). by Claudia Udine (224213)

“…Treatment of the mutants resulted in significantly higher reductions than treatment of the WT (p<0.05). In addition, supplementation resulted in a significant decrease in susceptibility compared to the unsupplemented mutant (p<0.05).…”

DataSheet_1_Differential Effects of Purinergic Signaling in Gastric Cancer-Derived Cells Through P2Y and P2X Receptors.pdf by María José Hevia (6833402)

“…Finally, in tumor-derived biopsies, we found an increase of P2Y₂R and a decrease in P2X4R expression; however, we found high variability between seven different biopsies and their respective adjacent healthy gastric mucosa. …”

Effects of Emulsion Formulations of Oleuropein Isolated from Ethanol Extract of Olive Leaf in Diabetic Rats by AHMET G. AGGUL (10365323)

Roles of individual genetic factors during repair of DSBs with non-cohesive ends generated by co-expression of I-SceI with Trex2. by Nicole Bennardo (93380)

“…Asterisks denote a statistical difference from EV (p<0.0001), and the dagger denotes a statistical difference from WT (p<0.0001). (B) Trex2 expression causes a decrease in HDR in cells deficient in Nbs1 and Brca1, but an increase in HDR in cells deficient in Xrcc4 and Msh2. …”

Overlap between apo and holo populations of LTPs can influence their transport rates. by Sriraksha Srinivasan (7535654)

“…<b>(b)</b> Mutations of GRAMD1A (5P), CPTP (V158N), and PITPA (P78L) that decrease their transport rates in vitro also reduce the similarities between apo and holo distributions. …”

Table 1_The global burden of aortic aneurysm in adults over 55: evolving trends, risk factors, and projections.pdf by Guoqian Ma (22253182)

“…</p>Results<p>Between 1990 and 2021, global AA-related deaths rose by 73.9% [from 79,608 (95% UI, 74,398–84,032) to 138,450 (123,754–149,214)], while the mortality rate declined by 21.4% (from 11.86 to 9.32 per 100,000). Similar patterns were observed for DALYs, with a 62.6% increase in total DALYs but a 26.5% decrease in rates. …”

Study flow and included patients. by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

Table 2_The global burden of aortic aneurysm in adults over 55: evolving trends, risk factors, and projections.pdf by Guoqian Ma (22253182)

“…</p>Results<p>Between 1990 and 2021, global AA-related deaths rose by 73.9% [from 79,608 (95% UI, 74,398–84,032) to 138,450 (123,754–149,214)], while the mortality rate declined by 21.4% (from 11.86 to 9.32 per 100,000). Similar patterns were observed for DALYs, with a 62.6% increase in total DALYs but a 26.5% decrease in rates. …”

Weaning parameters before planned extubation. by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults by Carrie V. Breton (74382)

“…Prenatal PM₁₀ and PM_2.5 exposures were associated with increased CAS. For example, a 2 SD increase in prenatal PM_2.5 was associated with CAS indices, including a 5% increase (β = 1.05, 95% CI 1.00–1.10) in carotid stiffness index beta, a 5% increase (β = 1.05, 95% CI 1.01–1.10) in Young’s elastic modulus and a 5% decrease (β = 0.95, 95% CI 0.91–0.99) in distensibility. …”

Supplementary Material for: Neuronal Nitric Oxide Synthase Inhibition Prevents Cerebral Palsy following Hypoxia-Ischemia in Fetal Rabbits: Comparison between JI-8 and 7-Nitroindazo... by Yu L. (3691228)

“…JI-8 was also significantly superior to saline in preserving smell, muscle tone and righting reflex function, but 7-NI did not show significant improvement. Furthermore, a 100-fold increase in the dose (15.75 µmol/kg) of 7-NI significantly decreased systolic blood pressure in the dam, while JI-8 did not. …”

S1 Data - by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

Baseline characteristics of enrolled patients. by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

NK cells are affected differently by allogeneic grafts depending on the course of rejection. by Oliver Beetz (6786137)

“…Syngeneic HTx served as a control group (n = 5). (B) Flow cytometric assessment of frequencies of NK cells in Lew wt and Lew.1a recipients after syngeneic and allogeneic HTx compared to naïve rats, respectively. …”

Minimal photobleaching of mbYFPQS occurs with repeated photo-stimulation. by Spencer D. Watts (327115)

“…<p>A. A cultured midbrain neuron expressing mbYFPQS was imaged with an exposure of 100 ms every 5 s for 35 min with less than 6% decrease in baseline fluorescence. …”

Mutation of S and T residues in the third intracellular loop increases intracellular cAMP. by Katie M. Lowther (427408)

“…The densitometric value for surface GPR3 was divided by the densitometric value for total GPR3 expression and normalized to β-actin to compare the amount of GPR3 at the surface vs. total GPR3 (<b>E</b>). (*) indicates a significant decrease in surface expression of GPR3 mutants compared to “WT”. …”