SB204741 restricts motion of pSRC. by James D. West (849663)

“…Values are expressed as mean ± standard error. n = 5–10, *p<0.05 compared to WT, #p<0.05 compared to vehicle treated.…”

Innate anxiety-like behavior is increased in NPYGAD1-TG mice. by Katelynn M. Corder (5537507)

“…(<b>D</b>) Distance traveled in the central zone (as a percent of total) and (<b>E</b>) ambulatory time in the central zone (as a percent of total) were decreased in NPYGAD1-TG male and female mice compared to NPYGAD1-WT mice, with no sex-dependent difference. …”

All mutants exhibit sensitivity to prolonged Ca²⁺-chelation. by Stefanie Bunse (491659)

“…Error bars indicate SEM. n(WT) = 84, n(W2A) = 56, n(R14E) = 84, n(V81D/V174D) = 52 junctions. …”

Table_1_Use of Non-invasive Parameters and Machine-Learning Algorithms for Predicting Future Risk of Type 2 Diabetes: A Retrospective Cohort Study of Health Data From Kuwait.DOCX by Bassam Farran (553880)

“…We aimed to build prognostic models for the risk of T2DM in the Arab population using machine-learning algorithms vs. conventional logistic regression (LR) and simple non-invasive clinical markers over three different time scales (3, 5, and 7 years from the baseline).</p><p>Design: This retrospective cohort study used three models based on LR, k-nearest neighbours (k-NN), and support vector machines (SVM) with five-fold cross-validation. …”

DataSheet1_I-κB kinase-ε deficiency improves doxorubicin-induced dilated cardiomyopathy by inhibiting the NF-κB pathway.pdf by Yafeng Liu (192716)

“…In many cardiovascular diseases, I-κB kinase-ε (IKKε) has been recognized as a pro-inflammatory molecule. In this study, wild-type mice (WT, n = 14) and IKKε knockout mice (IKKε-KO, n = 14) were intraperitoneally injected with a cumulative dose of 25 mg/kg with Dox or Saline five times in 30 days. …”

Use of Fixed Dose Combination (FDC) Drugs in India: Central Regulatory Approval and Sales of FDCs Containing Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Metformin, or Psychotro... by Patricia McGettigan (203640)

“…After 1 May 2002, the proportions of approved FDC formulations increased for NSAIDs (26%/28%) and anti-psychotics (0%/38%) and decreased for metformin (100%/75%) and anti-depressants/benzodiazepines (20%/18%), and the overall proportion approved remained similar before and after that date.…”

Sirt1 expression, deletion, and testing FAA in mice lacking Sirt1 in Pomc neurons. by Dina R. Assali (5447489)

“…<p>Immunostaining for Sirt1 in the adult mouse brain reveals a broad neuronal expression pattern: (A) CA1 region of the hippocampus (scale bar indicates 100 microns) and (B) low magnification image of the dorsal hypothalamus (scale bar indicates 500 microns), showing robust Sirt1 expression in the paraventricular nucleus. …”

Image_1_Optimizing estradiol level for gonadotrophin-releasing hormone antagonist initiation among patients with simple tubal factor infertility.jpg by Yizhuo Wang (5132726)

“…Through smooth curve fitting, we found that, with the increase of serum E₂ levels on the day of GnRH-ant initiation, CPR showed a trend of slight increase and then slight decrease. …”

Use of GPCR-HIT to show effect of AT₁ receptor activation on CCR2/Gα_i1 proximity. by Mohammed Akli Ayoub (176430)

“…The data are presented here as change in BRET signal as a percentage of CCL2-induced change for ease of interpretation. 100% is defined in each individual experiment as the decrease in BRET signal observed upon addition of 1 μM CCL2 (for curves with black circles), or 100 nM CCL2 + 1 pM AngII (for curves with white triangles). …”

Target species’ present day environmentally suitable space and predicted changes in short, medium, long term. by Rebecca Upson (3361301)

“…It is worth noting that % overlap in suitable environmental space would be 100% for the present day. For changes in environmentally suitable area available a value of < 100%, 100% or > 100% corresponds to a decrease, no alteration or increase.…”

Basic residue patches RRLRR and HRRRK are both required for membrane association of EHBP-1 NT-C2 domain. by Peixiang Wang (352425)

“…<b>(I)</b> Total area (per unit region) was quantified for GFP-labeled structures in <b>(A-F)</b>. Error bars are SEM (n = 18 each, 6 animals of each genotype sampled in three different regions of each intestine defined by a 100 x 100 (pixel²) box positioned at random). …”

Effects of etravirine on HIV-1 reverse transcriptase, recovered from plasma of HIV-1 infected patients. by Eva Agneskog (593818)

“…Based on the IC₅₀ value of BH10-wild-type (1.0±0.18 µM), which was included in every run, the IC₅₀ value and the fold-difference in susceptibility of each isolate were determined. A fold-difference of <5 was considered as sensitive, between 5–15 as decreased susceptibility, and above 15 as resistant.…”

Evaluation of anterior segment parameters using Scheimpflug technology during the Valsalva maneuver in patients with keratoconus by Yusuf Koçluk (5761517)

“…However, an increase in pupil diameter and a decrease in anterior chamber angle value were found. …”

Alpha activity induced by novel stimuli during REM sleep. by Perrine Ruby (486674)

“…Black dots on the topographies indicate electrodes showing a significant alpha increase or decrease compared to baseline.…”

Gonococci invasion of human macrophages is independent of CEACAM1. by Stanimir S. Ivanov (3394922)

“…The Internalization index for each condition was calculated by dividing the percentage of internalized objects from infections of the CEACAM1 KO U937 MFs cell line by the percentage of internalized objects from infections of the parental U937 MFs, which was then multiplied by 100. Values > 100% indicate increased object internalization by the KO cell line compared to WT cells, whereas values < 100% indicate decreased object internalization by the KO cell line. …”

The effect of dendritic distribution of CaL on PIC patterns and firing types. by Yi Cheng (317041)

“…<p><b>A.</b> PICs were induced by bi-ramp voltage when the dendritic length was extended to 100% (black, control), 300% (blue), and 500% (dark blue) with distal distribution of CaL. …”

Effect of deletion of the functional domains of INS-20 on <i>Cryptosporidium parvum</i>. by Yue Huang (285485)

“…<p>(A) Illustration of the native and modified loci within the <i>INS-20</i> gene for WT, INS-20ΔNter, INS-20ΔCter, and INS-20^HLLEQ/5A lines. …”

VtrB expression is under the control of VtrA. by Toshio Kodama (150168)

“…Lane 1, wild-type <i>V. parahaemolyticus</i> (WT); lane 2, <i>vtrA</i> mutant strain (WT<i>ΔvtrA</i>); lane 3, <i>vtrB</i> mutant strain (WT<i>ΔvtrB</i>); lane 4, <i>vtrA</i> and <i>vtrB</i> double mutant strain (WT<i>ΔvtrAΔvtrB</i>). …”

<i>Rps6</i>-deficiency induces p53 and disrupts rRNA processing. by Sarah A. Comerford (3854917)

“…<p>(A) Immunoblot of total protein lysates prepared from 2 WT (lanes 1 and 2) and 2 ΔS6 livers (lanes 3 and 4), p53-null Saos 2 cells (lane 5) and A431 cells that express high levels of mutant p53 (lane 6) with a p53-specific antibody and a GAPDH-specific antibody for load control. …”

Tracking Holocene drift-ice limits on the northwest–southwest Iceland shelf: Comparing proxy data with observation and historical evidence by John T. Andrews (6599843)