DataSheet_1_Regulation of SPDEF expression by DNA methylation in advanced prostate cancer.pdf by Mousa Vatanmakanian (15171089)

“…</p>Results<p>In this report, we observed that: a) there is a gradual decrease in SPDEF expression with a concomitant increase in methylated CpG sites within the SPDEF gene during prostate cancer progression from lower to higher Gleason grade; b) Expression of DNMT’s (DNMT1, 3a and 3b) is increased during prostate cancer progression, and there is an inverse correlation between SPDEF and DNMT expression; c) SPDEF levels are decreased in RC77/T, a line of PCa cells from African American origin similar to PC3 and DU145 cells (CRPC cells), as compared to LNCaP cells , a line of androgen dependent cells,; d) the 5′ CpG island of SPDEF gene are hypermethylated in SPDEF-negative CRPC ( PC3, DU145 and RC77/T) cell lines but the same regions are hypomethylated in SPDEF-positive castrate sensitive (LNCaP) cell line ; (e) expression of SPDEF in PCa cells lacking SPDEF decreases cell migration and invasion, but has no significant effect on cell proliferation, and; (f) treatment with the demethylating agent, 5-aza-2′-deoxycytidine, or silencing of the DNMT’s by siRNA, partially restores SPDEF expression in SPDEF-negative PCa cell lines, and decreases cell migration and invasion.…”

File S1 - Post-Transcriptional Regulator Hfq Binds Catalase HPII: Crystal Structure of the Complex by Koji Yonekura (480516)

“…The representation scheme of molecules is the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0078216#pone-0078216-g005" target="_blank">Fig. 5</a>. …”

DataSheet_1_Optimizing linear energy transfer distribution in intensity-modulated proton therapy using the alternating direction method of multipliers.pdf by Qingkun Fan (17379391)

“…</p>Results<p>The results demonstrate the superiority of ADMM-LET over ICR-LET in terms of LET distribution while achieving a comparable dose distribution. More specifically, for the brain case, the maximum LET (unit: keV/µm) at the optic nerve decreased from 5.45 (ICR-LET) to 1.97 (ADMM-LET). …”

BPLF1 promotes the accumulation of SUMOylated TOP2ccs and cell viability following Etoposide treatment. by Jinlin Li (2267896)

“…<p><b>(A)</b> HEK-rtTA-BPLF1 cells were cultured for 24 h in the presence or absence of 1.5 μg/ml Dox and then treated with 80 μM Etoposide for 30 min followed by detection of DNA trapped TOP2 by RADAR assay. …”

Table 1_Comparative effectiveness and safety of GATT with or without ABiC in patients with open-angle glaucoma.docx by Weijia Zhang (79845)

“…The number of medications was 0.6 ± 1.0 in Group 1 and 0.9 ± 1.3 in Group 2 (p = 0.334). At 24 months, the mean IOP was 15.3 ± 2.0 mmHg in Group 1 and 15.5 ± 2.4 mmHg in Group 2 (p = 0.676). …”

DataSheet1_Bayesian denoising algorithm dealing with colored, non-stationary noise in continuous glucose monitoring timeseries.docx by Nunzio Camerlingo (9394596)

“…</p><p>Results: On D_S1, BD allows reducing the root-mean-square-error (RMSE) from 8.10 [6.79–9.24] mg/dL to 6.28 [5.47–7.27] mg/dL (median [IQR]); on D_S2, RMSE decreases from 6.85 [5.50–8.72] mg/dL to 5.35 [4.48–6.49] mg/dL. …”

From melanoma and nevus to volatile signatures. by Tatjana Abaffy (35871)

“…A peak of 2,5 dimethyl benzenamine is shown eluting at 17.8 min. …”

Calcium release caused by 9.2.27PE±ABT-737 in melanoma cells. by Karianne Risberg (207221)

“…<p>(A) FEMX, Melmet-5 and MelRM cells were subjected to 9.2.27PE (100 ng/ml)+ABT-737 (10 µM) for 16 and 24 h before subjected to flow cytometric analysis using Calcium Green™-1. …”

Effect of E protein on the recognition of prM protein by human anti-prM mAbs. by Wen-Yang Tsai (108058)

“…<p>(A) Binding specificity of 4 human anti-prM mAbs including 2 CR (DVB59.3 and DVB18.5) and 2 sCR (DVB65.5 and DVB32.4) mAbs was determined as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052600#pone-0052600-g005" target="_blank">Figure 5</a>. …”

Dataset for Mathematical Model of in vitro Hepatocellular Cholesterol and Lipoprotein Metabolism, fig. 7 by Yuri Efremov (8450409)

Release rates of essential oils. by Thummanoon Boonmee (17935566)

“…In the 2^nd experiment, the application of plasma-treated cardboard pieces impregnated with 5% (v/v) clove oil induced a 38.10% reduction in the population of <i>Varroa</i> mites followed by 5% (v/v) of cardamon with 30% efficiency. …”

Evaporation rates of cinnamon essential oil. by Thummanoon Boonmee (17935566)

“…In the 2^nd experiment, the application of plasma-treated cardboard pieces impregnated with 5% (v/v) clove oil induced a 38.10% reduction in the population of <i>Varroa</i> mites followed by 5% (v/v) of cardamon with 30% efficiency. …”

Pro-apoptotic effect of burns septic acute renal failure (ARF) group plasma on tubular cells and correlation with proteinuria by Filippo Mariano (11845)

“…Plasma from burns septic ARF group patients induced a dose-dependent decrease of tubular cell viability (XTT-based assay, n = 19, *p < 0.05 burns septic ARF group plasma 2.5%, 5% or 10% vs control healthy plasma). …”

Table2_An integrative analysis of the lncRNA-miRNA-mRNA competitive endogenous RNA network reveals potential mechanisms in the murine hair follicle cycle.DOCX by Yuxin Ding (4737072)

“…Our analysis revealed 11 miRNAs (miR-148a-3p, miR-146a-5p, miR-200a-3p, miR-30e-5p, miR-30a-5p, miR-27a-3p, miR-143-3p, miR-27b-3p, miR-126a-3p, miR-378a-3p, and miR-22-3p), 9 target mRNAs (Atp6v1a, Cdkn1a, Gadd45a, Gspt1, Mafb, Mitf, Notch1, Plk2, and Slc7a5), and 2 target lncRNAs (Neat1 and Tug1) were differentially expressed in hair follicle cycling. …”

Expression analyses of HSPG and integrin molecules as alternate receptors for fiber-modified Ads on AI-WAm cells. by Anton V. Borovjagin (342382)

“…<p>Expression of α_vβ3 and α_vβ5 integrins (<b>A</b> and <b>B</b>) and heparin sulfate proteoglycans (<b>C–E</b>) in AI-WAm cell population and control cells was analyzed by flow cytometry (<b>A</b>, <b>C</b>, <b>E</b>) and IHC staining (<b>B</b> and <b>D</b>). …”

Table1_An integrative analysis of the lncRNA-miRNA-mRNA competitive endogenous RNA network reveals potential mechanisms in the murine hair follicle cycle.DOCX by Yuxin Ding (4737072)

“…Our analysis revealed 11 miRNAs (miR-148a-3p, miR-146a-5p, miR-200a-3p, miR-30e-5p, miR-30a-5p, miR-27a-3p, miR-143-3p, miR-27b-3p, miR-126a-3p, miR-378a-3p, and miR-22-3p), 9 target mRNAs (Atp6v1a, Cdkn1a, Gadd45a, Gspt1, Mafb, Mitf, Notch1, Plk2, and Slc7a5), and 2 target lncRNAs (Neat1 and Tug1) were differentially expressed in hair follicle cycling. …”

Table3_An integrative analysis of the lncRNA-miRNA-mRNA competitive endogenous RNA network reveals potential mechanisms in the murine hair follicle cycle.DOCX by Yuxin Ding (4737072)

“…Our analysis revealed 11 miRNAs (miR-148a-3p, miR-146a-5p, miR-200a-3p, miR-30e-5p, miR-30a-5p, miR-27a-3p, miR-143-3p, miR-27b-3p, miR-126a-3p, miR-378a-3p, and miR-22-3p), 9 target mRNAs (Atp6v1a, Cdkn1a, Gadd45a, Gspt1, Mafb, Mitf, Notch1, Plk2, and Slc7a5), and 2 target lncRNAs (Neat1 and Tug1) were differentially expressed in hair follicle cycling. …”

The effects of intensified training on resting metabolic rate (RMR), body composition and performance in trained cyclists by Amy L. Woods (3839215)

“…Data were analysed using a linear mixed modeling approach.</p><p>Results</p><p>The intensified training period elicited significant decreases in RMR (F_(5,123.36) = 12.0947, p = <0.001), body mass (F_(2,19.242) = 4.3362, p = 0.03), fat mass (F_(2,20.35) = 56.2494, p = <0.001) and HRV (F_(2,22.608) = 6.5212, p = 0.005); all of which improved following a period of recovery. …”

Table4_An integrative analysis of the lncRNA-miRNA-mRNA competitive endogenous RNA network reveals potential mechanisms in the murine hair follicle cycle.DOCX by Yuxin Ding (4737072)

“…Our analysis revealed 11 miRNAs (miR-148a-3p, miR-146a-5p, miR-200a-3p, miR-30e-5p, miR-30a-5p, miR-27a-3p, miR-143-3p, miR-27b-3p, miR-126a-3p, miR-378a-3p, and miR-22-3p), 9 target mRNAs (Atp6v1a, Cdkn1a, Gadd45a, Gspt1, Mafb, Mitf, Notch1, Plk2, and Slc7a5), and 2 target lncRNAs (Neat1 and Tug1) were differentially expressed in hair follicle cycling. …”

Proteasome function is impaired by mutant or loss of PINK1. by Wencheng Liu (374270)

“…There was a statistically significant decrease of proteasome activity in the SH-SY5Y cells expressing L347P-PINK1 (23% reduction, n = 7, p = 0.018, paired student t test) or in SH-SY5Y cells expressing E417G-PINK1 (19.4% reduction, n = 8, p = 0.012, paired student t test) compared to cells expressing wild type PINK1. …”