Mutant huntingtin actions on GABAA receptors and NMDA receptors by Alison Twelvetrees (467856)

Figure 3 by Feng Bai (336697)

“…Thresholds were set at a corrected <i>P</i><0.05, determined by Monte Carlo simulation. (3) Overlap regions (PCC/Pcu) between baseline changes and longitudinal changes of DMN IC were observed in aMCI group compared to controls. (4) Hyper-functional connectivity between the PCC/PCu (overlap regions) and mean DMN IC in baseline aMCI subjects, and significant hypo-connections of these regions were in follow-up aMCI subjects, whilst controls only showed a light decreases at the longitudinal period. * <i>P</i><0.05 (0.046); ** <i>P</i><0.001(0.000). (5) Correlative analysis: within the aMCI group, the decreases of functional connectivity between PCC/PCu and mean DMN IC were positively related to the impairments of episodic memory (AVLT-delayed recall scores, r = 0.462, <i>P</i> = 0.018, two-tailed) from baseline to follow up. …”

Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response by Xue, Mingzhan

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Silibinin improves palmitate-induced insulin resistance in C2C12 myotubes by attenuating IRS-1/PI3K/Akt pathway inhibition by H.B. Li (6514220)

Titration and characteristics of pressure-support ventilation use in Argentina: an online cross-sectional survey study by Joaquin Pérez (10437650)

Graphene oxide nanoparticles induce hepatic dysfunction through the regulation of innate immune signaling in zebrafish (<i>Danio rerio</i>) by Guanghua Xiong (8543577)

Effects of Dietary Supplementation of Soy Isoflavones on the Performance and Egg Quality in Native Chinese Breeder Hens by E Abdelghani (8183238)

Androgen receptor gene deficiency results in the reduction of steroidogenic potential in porcine luteal cells by Jaya Bharati (12843349)

Effects of TO901317 on apoptosis. by Irene Paterniti (310894)

“…<p>The results underlined that Bax expression was considerably enhanced in the MPTP group (b, b1 see densitometry analysis g, and Figure b in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0174470#pone.0174470.s005" target="_blank">S5 File</a>) whereas treatment with TO901317 significantly limited the rise in Bax expression (c,c1 see densitometry analysis g and Figure c in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0174470#pone.0174470.s005" target="_blank">S5 File</a>). …”

Influenza prevalence and vaccine efficacy among diabetic patients in Qatar by Swapna, Thomas

“…Among the typed IVA-positive cases, 33.4% were H1N1, and 7.7% were H3N2. A significant decrease in influenza infections was reported in vaccinated DM patients (14.5%) when compared to non-vaccinated patients (18.9%) (p-value = 0.006). …”
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C6-ceramide nanoliposomes target GAPDH in CLL. by Lindsay K. Ryland (499850)

“…Densitometry analysis from replicate experiments (n=4) was performed via ImageJ software. In Figure A(ii) the representative blot demonstrates a decrease in GAPDH at 12.5µM C6-ceramide, a result not observed in the other two distinct replicate experiments. * <i>P</i> < 0.05; ** <i>P <0 .005</i>. …”

Data_Sheet_1_One Century of Forest Monitoring Data in Switzerland Reveals Species- and Site-Specific Trends of Climate-Induced Tree Mortality.docx by Sophia Etzold (6496022)

“…However, tree mortality at the ecosystem level remains challenging to quantify since long-term, tree-individual, reliable observations are scarce. Here, we present a unique data set of monitoring records from 276 permanent plots located in 95 forest stands across Switzerland, which include five major European tree species (Norway spruce, Scots pine, silver fir, European beech, and sessile and common oak) and cover a time span of over one century (1898–2013), with inventory periods of 5–10 years. …”

Theoretical and Experimental Study of 3‑Pentanol Autoignition: Ab Initio Calculation, Shock Tube Experiments, and Kinetic Modeling by Yuan Feng (213823)

“…Furthermore, using an ST, ignition delay times (IDTs) for the 3-pentanol/air mixtures were measured spanning a temperature range of 920–1450 K, pressures of 6, 10, and 20 bar, and equivalence ratios of 0.5, 1.0, and 1.5. …”

Data_Sheet_1_Investigating the Binding Heterogeneity of Trace Metal Cations With SiO2 Nanoparticles Using Full Wave Analysis of Stripping Chronopotentiometry at Scanned Deposition... by Elise Rotureau (1611436)

“…Nonetheless, this might change for nanoparticulate systems as observed in a previous study of Pb(II) with a very small SiO₂ particle (7.5 nm diameter). …”

Serology for Trachoma Surveillance after Cessation of Mass Drug Administration by Diana L. Martin (300642)

“…Among 1–9 year olds, TF prevalence was 6.5%, whereas only 3.5% were seropositive. Force of infection modelling indicated a 10-fold decrease in seroconversion rate at a time corresponding to MDA commencement. …”

Scheme detailing the experiment design using Apoatã, Icatu, and Obatã plants. by José C. Ramalho (493978)

“…Thereafter, plants were exposed to 1) a gradual temperature decrease from 25/20°C to 13/8 ^oC, over 24 days (0.5°C/day), 2) to a 3 days chilling cycle (3x13/4 ^oC), where 4 ^oC were applied during the night and in the first 4 h of the morning (with light), followed by a rise up to 13 ^oC, throughout the rest of the diurnal period, 3) a rewarming period of 7 days (7x Rec Cold), with the first day after chilling at 20/15 ^oC and the rest at 25/20 ^oC, 4) followed by a fully rewatering of all plants, which were allowed to recover for another period of 7 days (7x Rec Drought). …”

Data_Sheet_1_Determination of Microbial Maintenance in Acetogenesis and Methanogenesis by Experimental and Modeling Techniques.zip by Fabian Bonk (5826242)

“…We hypothesized that a decrease in dilution rate might select taxa with minimized maintenance expenditure. …”

Flow diagram of exclusion criteria. by Mariet Benade (13943917)

“…Multivariable regression showed that participants with incident hypertension in 2017 were 3.01 (95%CI 1.77, 5.13) times more likely to have a controlled blood pressure compared to those in 2011. …”

Sociodemographic characteristics of the sample. by Lindsey Smith Taillie (3159258)

“…Effects on purchase intentions were smaller, with a 6% decrease for unsustainable products (p = 0.001) and an 8% increase for sustainable products (p<0.001). …”

DataSheet1_Human organoids are superior to cell culture models for intestinal barrier research.docx by Catherine Kollmann (17077822)

“…<p>Loss of intestinal epithelial barrier function is a hallmark in digestive tract inflammation. The detailed mechanisms remain unclear due to the lack of suitable cell-based models in barrier research. …”