Search alternatives:
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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High-throughput drug screen reveals HDAC and proteasome inhibitors as potent drug classes against synovial sarcoma.
Published 2017“…<p>(A) Compounds resulting in measured relative cell viability of less than 50% are annotated as hits (blue). …”
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1768
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1769
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1770
Lysine 50 of Tat regulates expression of C5, CRLF2, APBA1, and BDNF genes.
Published 2017“…<p>THP-1Tat-Flag and THP-1Tat K50ATat-Flag cell lines (generated from independent experiments described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0179882#pone.0179882.g005" target="_blank">Fig 5</a>) were differentiated to macrophages with PMA for 24 and 48 hours. …”
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1771
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HDAC inhibition prevents aggresome formation in response to proteasome inhibitors, and combination treatment leads to endoplasmic reticulum stress.
Published 2017“…<p>(A) Knockdown of HDAC6 results in decreased levels of LC3B in the SYO-1 synovial sarcoma cell line. …”
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The conserved phenylalanine residue in PRMT5 is critical for inhibition by the five compounds.
Published 2017“…<p>A, DS-PAGE of recombinant wild type (WT) and F225M mutant (MT) PRMT5. …”
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1780