Systemic metabolic switch and glycogen breakdown are required for effective resistance to <i>Streptococcus pneumoniae</i>. by Adam Bajgar (730380)

Epigenetic adaptation of the placental serotonin transporter gene (<i>SLC6A4</i>) to gestational diabetes mellitus by Sofia Blazevic (4173319)

“…<div><p>We tested the hypothesis that gestational diabetes mellitus (GDM) alters the DNA methylation pattern of the fetal serotonin transporter gene (<i>SLC6A4</i>), and examined the functional relevance of DNA methylation for regulation of the <i>SLC6A4</i> expression in the human placenta. …”

NIF significantly decreases diabetes-induced leukostasis in the retinal vasculature. by Alexander A. Veenstra (474665)

Correlation between decrease in methylation levels and increase in t-PA expression. by Mia Magnusson (182244)

Inhibition of ACC leads to decreased de novo lipogenesis in both U87 and U87 EGFRvIII but reduced the number of U87 EGFRvIII cells to a greater extent. by Jessica E. C. Jones (541168)

(<i>S</i>)-PZQ decrease tone of contracted mesenteric arteries. by Gihan S. Gunaratne (5117795)

mTOR inhibition with rapamycin decreases MEC survival and branching. by Meghan M. Morrison (683792)

Expanding Three-Coordinate Gold(I) Anticancer Agent Chemical Space by Charles E. Greif (21728091)

“…The complexes demonstrated submicromolar cytotoxic activity against human breast cancer cells MDA-MB-231 or MDA-MB-468 with IC₅₀’s in the range of 0.4–5.0 μM. Complex <b>2e</b> shows high potency in vitro and decreases 3D-breast cancer mammosphere viability. …”

Src Family Kinases Modulate the Loss of Endothelial Barrier Function in Response to TNF-α: Crosstalk with p38 Signaling by Alejandro P. Adam (55143)

“…Treatment of DN-Csk-expressing cells with 50 pg/ml TNF-α induced a loss of TEER as well as drastic changes in the actin cytoskeleton and focal adhesion proteins. …”

PAD4-deficient mice display a slight decrease in weight loss upon influenza infection but similar survival kinetics. by Saskia Hemmers (214438)

Increase in the amount of AGEs in the silkworm hemolymph after ingestion of a high glucose diet and decrease in AGEs after injection of aminoguanidine. by Yasuhiko Matsumoto (206628)

Decreased CSF cytokine levels in α7 KO mice. by Feng Chi (170688)

Decrease in GABA_B expression in APP mice. by Ksenia V. Kastanenka (3692380)

Stress can increase or decrease anxiety depending on the timing of the stressor by Jason Snyder (96580)

PGRN deficiency results in decreased GCase activity in mouse tissues. by Xiaolai Zhou (3547520)

Hepatic steatosis was dramatically decreased in CD44KO(HFD). by Hong Soon Kang (386679)

Effect of decreased endogenous betaglycan expression on metanephric development and glomerulogenesis. by Kenneth A. Walker (280683)

MicroRNA-193a inhibits breast cancer proliferation and metastasis by downregulating WT1 by FeiYan Xie (4503430)

“…In this study, we found decreased miR-193a (specifically, miR-193a-5p) expression not only in breast cancer cell lines but also in breast cancer tissues as compared with the adjacent non-tumor tissues. …”

Decreased translation efficiency of DENV reporter constructs by RyDEN. by Youichi Suzuki (407067)

MVEC viability is decreased over time in PEG-based hydrogels. by Rebecca A. Scott (488956)