Effects of the Pgp inhibitor tariquidar (TQ; 0.5 µM) in three functional assays, in which alterations in Pgp efflux are indirectly measured by determining intracellular concentrati... by Andreas Noack (519906)

“…In the absence of doxycycline (open columns), tariquidar significantly increased Rho123 accumulation (i.e., decreased Rho123 efflux) by only about 15%. In the presence of doxycycline, accumulation of Rho123 was only about 50% of that under doxycycline-off conditions, which was completely counteracted by tariquidar. …”

Ribosome footprinting and polysome profiling reveal DUX4 suppressive effects on translation efficiency. by Danielle C. Hamm (4693915)

“…Volcano plot showing log2 fold-change differential polysome abundance in cells treated with DUX4 pulse+IFNγ harvested at 68 hours versus IFNγ (significance defined as basemean>50, |log2FC>1|, p-adj<0.01); see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002317#pbio.3002317.s012" target="_blank">S4 Data</a>. …”

Physiological and behavioural aspects of climate change vulnerability in ground-foraging passerines inhabiting South Africa’s Tankwa Karoo desert by James Short (20291754)

“…Large-billed larks displayed a thermoregulatory capacity comparable to that associated with most desert birds studied to date, possessing a MaxTb of ~ 45°C and an HTL of ~50°C. …”

Impact of yield threshold (σ_<i>y</i>) and extensibility (Φ) variations on <i>Ectocarpus</i> tip growth. by Hervé Rabillé (6204806)

“…The curve shows that both σ_y and Ф are affected by the presence of IAA: σ_y decreases while Ф increases, both modifications corresponding to a cell wall–loosening effect. …”

Image_2_Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome.tif by Harshit Singh (6724346)

“…Compared to baseline, TSA treatment increased mRNA levels of P-gp and MRP-1 (fold change 7.51, 7.31, ^*p < 0.0001 in SRNS) and (fold change 3.49, 3.35, ^*p < 0.0001 in SSNS), respectively. It significantly decreased the level of HDAC2 (fold change 1.50, ^*p < 0.0001 in SRNS) (fold change 2.53, ^*p < 0.0001 in SSNS) patients.…”

Image_4_Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome.tif by Harshit Singh (6724346)

“…Compared to baseline, TSA treatment increased mRNA levels of P-gp and MRP-1 (fold change 7.51, 7.31, ^*p < 0.0001 in SRNS) and (fold change 3.49, 3.35, ^*p < 0.0001 in SSNS), respectively. It significantly decreased the level of HDAC2 (fold change 1.50, ^*p < 0.0001 in SRNS) (fold change 2.53, ^*p < 0.0001 in SSNS) patients.…”

Image_3_Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome.tif by Harshit Singh (6724346)

“…Compared to baseline, TSA treatment increased mRNA levels of P-gp and MRP-1 (fold change 7.51, 7.31, ^*p < 0.0001 in SRNS) and (fold change 3.49, 3.35, ^*p < 0.0001 in SSNS), respectively. It significantly decreased the level of HDAC2 (fold change 1.50, ^*p < 0.0001 in SRNS) (fold change 2.53, ^*p < 0.0001 in SSNS) patients.…”

Image_1_Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome.tif by Harshit Singh (6724346)

“…Compared to baseline, TSA treatment increased mRNA levels of P-gp and MRP-1 (fold change 7.51, 7.31, ^*p < 0.0001 in SRNS) and (fold change 3.49, 3.35, ^*p < 0.0001 in SSNS), respectively. It significantly decreased the level of HDAC2 (fold change 1.50, ^*p < 0.0001 in SRNS) (fold change 2.53, ^*p < 0.0001 in SSNS) patients.…”

<i>Theileria annulata</i> parasites with M128I mutation in cytochrome B (<i>Ta</i>M128I) resist buparvaquone treatment. by Shahin Tajeri (3609266)

“…A clear right shift in dose-response curve resulted from decreased susceptibility of macrophages transformed by <i>Ta</i>M128I parasite compared to the wild type is detectable. …”

Activity and Reactivity of Fe²⁺ Cations in the Zeolite. Ab Initio Free-Energy MD Calculation of the N₂O Dissociation over Iron-Exchanged Ferrierite by Lubomir Benco (1987384)

“…The MD simulations show that the bivalent Fe²⁺ cation can induce a local deformation of the zeolite framework, which cannot be observed experimentally. …”

AOX inhibitor supresses growth of <i>T</i>. <i>hominis</i> cells inside the RK13 host cells at early meront stages of the infection, and affects the ability to infect by the spores... by Kacper M. Sendra (14285356)

“…<p>Effects of the two clinically used anti-microsporidian drugs (albendazole, 350 nM; and fumagillin, 200 nM), and an inhibitor of the AOX Colletochlorin B (CCB, 50 μM) on progression of the parasite life cycle were tested in a synchronised time course of infection in <i>T</i>. …”

Increased aggregation propensity enhances Pept-in antimicrobial potency by promoting Pept-in accumulation and IB formation. by Guiqin Wu (760045)

“…This figure is associated with data from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0283674#pone.0283674.s009" target="_blank">S3 Table</a>. …”

S1 Data - by Renjie Wang (1986553)

“…Notably, moderate (D2) and severe (D3) drought treatments led to negative GD values. GD decreased by 23.79%, 114.85%, and 175.50% for D1, D2, and D3 treatments, respectively, while reductions of 40.00%, 73.33%, and 90.00% in GD were observed compared to the control (CK). …”

S3 Data - by Renjie Wang (1986553)

“…Notably, moderate (D2) and severe (D3) drought treatments led to negative GD values. GD decreased by 23.79%, 114.85%, and 175.50% for D1, D2, and D3 treatments, respectively, while reductions of 40.00%, 73.33%, and 90.00% in GD were observed compared to the control (CK). …”

S2 Data - by Renjie Wang (1986553)

“…Notably, moderate (D2) and severe (D3) drought treatments led to negative GD values. GD decreased by 23.79%, 114.85%, and 175.50% for D1, D2, and D3 treatments, respectively, while reductions of 40.00%, 73.33%, and 90.00% in GD were observed compared to the control (CK). …”

S5 Data - by Renjie Wang (1986553)

“…Notably, moderate (D2) and severe (D3) drought treatments led to negative GD values. GD decreased by 23.79%, 114.85%, and 175.50% for D1, D2, and D3 treatments, respectively, while reductions of 40.00%, 73.33%, and 90.00% in GD were observed compared to the control (CK). …”

S6 Data - by Renjie Wang (1986553)

“…Notably, moderate (D2) and severe (D3) drought treatments led to negative GD values. GD decreased by 23.79%, 114.85%, and 175.50% for D1, D2, and D3 treatments, respectively, while reductions of 40.00%, 73.33%, and 90.00% in GD were observed compared to the control (CK). …”

S4 Data - by Renjie Wang (1986553)

“…Notably, moderate (D2) and severe (D3) drought treatments led to negative GD values. GD decreased by 23.79%, 114.85%, and 175.50% for D1, D2, and D3 treatments, respectively, while reductions of 40.00%, 73.33%, and 90.00% in GD were observed compared to the control (CK). …”

S7 Data - by Renjie Wang (1986553)

“…Notably, moderate (D2) and severe (D3) drought treatments led to negative GD values. GD decreased by 23.79%, 114.85%, and 175.50% for D1, D2, and D3 treatments, respectively, while reductions of 40.00%, 73.33%, and 90.00% in GD were observed compared to the control (CK). …”

Table_1_Durability of immune response after SARS-CoV-2 vaccination in patients with chronic liver disease.docx by Ruixin Song (15399459)

“…Within 30 days of booster immunization, the positive rates of nCoV NTAb and nCoV S-RBD in patients with CLD rapidly increased from 29.0% and 48.4% at the end of basic immunization to 95.2% and 90.5%, and maintained a high level (defined as the positive rate >50%) until 120 days when the positive rates of nCoV NTAb and nCoV S-RBD were still high at 79.5% and 87.2%, respectively. …”