Ischemic preconditioning (IPC) does not occur in Cav-1 KO mice. by Brian P. Head (343968)

“…Representative Cresyl Violet stained CA1 hippocampal images from (<b>i</b>) WT sham, (<b>ii</b>) WT IPC, (<b>iii</b>) WT LI, and (<b>iv</b>) WT IPC and (<b>v</b>) Cav-1 KO sham, (<b>vi</b>) Cav-1 KO IPC, (<b>vii</b>) Cav-1 KO LI, and (<b>viii</b>) Cav-1 KO IPC. …”

Figure 1. ARRB1 is downregulated in human IPAH and loss of ARRB1 in mice results in worsened hypoxia-induced PAH. by Zhiyuan Ma (6441500)

“…(<b>i</b>) Representative images of immunofluorescence for smooth muscle a-actin (a-SMA, red), von Willebrand’s factor (VWF, green) and nuclei (blue) in lung sections from WT, <i>Arrb1</i> KO and <i>Arrb2</i> KO mice exposed to hypoxia (scale bar = 50 μm). …”

Stabilization of the Skeletal Muscle Ryanodine Receptor Ion Channel-FKBP12 Complex by the 1,4-Benzothiazepine Derivative S107 by Yingwu Mei (102313)

“…The 1,4-benzothiazepine derivative JTV519, and the more specific derivative S107 <b>(</b>2,3,4,5,-tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine), are thought to improve skeletal muscle function by stabilizing the RyR1-FKBP12 complex. Here, we report a high degree of nonspecific and specific low affinity [³H]S107 binding to SR vesicles. …”

Table_1_Gut-microbiome-based predictive model for ST-elevation myocardial infarction in young male patients.XLSX by Mingchuan Liu (7040438)

Data_Sheet_1_Gut-microbiome-based predictive model for ST-elevation myocardial infarction in young male patients.docx by Mingchuan Liu (7040438)

DataSheet1_Spatio-temporal characteristics of PM2.5 and O3 synergic pollutions and influence factors in the Yangtze River Delta.docx by Qing Zhu (349093)

Inclusion and exclusion table. by Tong-jie Yang (20939652)

“…</p><p> Methods </p><p>We conducted a comprehensive literature search on MEDLINE/PubMed, EMBASE, Google Scholar, SpringerLink, Scops, Web of Science, and Bentham Science Publishers from inception to January 2024, following the PRISMA guidelines, to retrieve all studies relevant to the application of HU in assessing both bone and soft tissue quality of the proximal femur, particularly in the context of ONFH and THA. …”

Included studies. by Tong-jie Yang (20939652)

“…</p><p> Methods </p><p>We conducted a comprehensive literature search on MEDLINE/PubMed, EMBASE, Google Scholar, SpringerLink, Scops, Web of Science, and Bentham Science Publishers from inception to January 2024, following the PRISMA guidelines, to retrieve all studies relevant to the application of HU in assessing both bone and soft tissue quality of the proximal femur, particularly in the context of ONFH and THA. …”

Inclusion and exclusion criteria. by Tong-jie Yang (20939652)

“…</p><p> Methods </p><p>We conducted a comprehensive literature search on MEDLINE/PubMed, EMBASE, Google Scholar, SpringerLink, Scops, Web of Science, and Bentham Science Publishers from inception to January 2024, following the PRISMA guidelines, to retrieve all studies relevant to the application of HU in assessing both bone and soft tissue quality of the proximal femur, particularly in the context of ONFH and THA. …”

Homolog pairing and sister chromatid cohesion in interphase remain unaffected genome-wide after knockdown of Rad21. by T. Niroshini Senaratne (3067776)

“…A simple separation of sister chromatids would be expected to cause a decrease in the percentage of nuclei with a single FISH signal, or an increase in the area of FISH signals; we observed neither (see main text for details).…”

ECG analyses of urethane anaesthetized Ts65Dn adult mice revealed cardiac conduction anomalies. by Matthieu Raveau (160575)

“…Measurement of wave amplitudes in precordial leads (G) showed a large decrease of S and J waves on V1 and limited changes in V4 whereas R waves were found normal in both V1 and V4 (n = 31 and 29 for wt and Ts65Dn respectively) (Student t-test p-values: **: <i>P</i><0.01; ***: <i><u>P</u></i><0.001).…”

Image_1_Interleukin 23 Produced by Hepatic Monocyte-Derived Macrophages Is Essential for the Development of Murine Primary Biliary Cholangitis.jpeg by Debby Reuveni (5633135)

<i>ACVR2</i> promoter hypermethylation and LOH in colon cancer specimens and the MSS HT29 cell line and correlation of <i>ACVR2</i> promoter hypermethylation and loss of <i>ACVR2</... by Barbara Jung (155690)

“…<p>A) ACVR2 promoter with map of positioning of MSP primers B) Using a CpG islands search program, we identified the CpG islands within the <i>ACVR2</i> promoter based upon following stringent criteria: ∼CG percentage>55%; observed CpG/expected CpG >0.65; length >500 bp. …”

Table_1_The safe lowest effective power of subthreshold micropulse laser treatment in Chinese patients with acute or chronic central serous chorioretinopathy.DOCX by Ting Xie (191025)

“…We found that the lowest effective laser power for acute CSC was 425 mW (−225.50 μm vs. −171.24 μm vs. −114.50 μm vs. −130.54 μm vs. −68.00 μm, p < 0.001), showing a significant CMT reduction at this power, but no significant increase in BCVA (−0.15 ± 0.10 logMAR vs. −0.20 ± 0.16 logMAR vs. −0.14 ± 0.11 logMAR vs. −0.17 ± 0.30 logMAR vs. −0.11 ± 0.14 logMAR, p > 0.05). …”

The <i>PIGA</i>c.1234C>T mutation increases <i>PIGA</i> function compared to <i>PIGA</i>null hiPSCs. by Xuan Yuan (225365)

“…Intensity of Smad 1/5/8 phosphorylation was comparably increased following BMP4 induction in both of PIGA<i>wt</i> hiPSCs and <i>PIGA</i>c.1234C>T hiPSCs; decreased responsiveness to BMP4 induction was observed in <i>PIGA</i>null hiPSCs as previously described. β -actin was used as an internal control.…”

GPI anchored proteins are required for neural differentiation. by Xuan Yuan (225365)

“…Neural induction and rosette formation upon neural induction was assessed in three cell lines using a serum-free EB generation method. On day 2 (left) of hiPSC-derived EBs from <i>PIGA</i>wt, <i>PIGA</i>c.1234C>T, and <i>PIGA</i>null after forced aggregation (20X magnification, scale bar is 50μm). …”

Mef2C is regulated during neurogenesis, in turn contributing to miR-9 induction. by Jonathan L. Davila (548756)

“…(C) Deletion of Mef2 binding sites in the upstream regulatory region diminishes transcription activity of the miR-9-2 gene locus. A 5 kb upstream sequence of the rat miR-9-2 gene was cloned into the promoter-less pGL4.10 luciferase reporter vector (wild-type, WT). …”

Comparison of qualitative experimental input–output relations and model predictions. by Linda Irons (9292686)

“…Model predicted absolute differences in steady state species activity when the inputs (intramural stress, wall shear stress (Wss), and AngII) are perturbed relative to baseline: orange denotes an increase and blue a decrease relative to the original steady state (white). …”

Tau knockout prevents sensitivity to Kainic acid–mediated stress in AICD-Tg mice. by Kaushik Ghosal (244754)

“…Mean seizure severity scores showed a significant rescue of seizure severity by Tau-/- in AICD animals. n = 4–5 mice per group (A-C). …”

Intrachromatid and intersister (IC/IS) bias in <i>URA3</i> inactivation. by James D. Cauwood (481139)

“…</b> Frequencies of IC/IS, IH, ECT, and other mechanisms of <i>URA3</i> inactivation in 5FOA^R colonies. Numbers in blue and red in panel <b>J</b> denote statistically significant decrease and increase conferred by HU compared to YPD, respectively.…”