Table_4_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.xlsx by Michelle L. D'Antoni (8058620)

“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”

Table_6_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.xlsx by Michelle L. D'Antoni (8058620)

“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”

Image_2_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.TIF by Michelle L. D'Antoni (8058620)

“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”

Image_1_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.TIFF by Michelle L. D'Antoni (8058620)

“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”

Table_7_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.xlsx by Michelle L. D'Antoni (8058620)

“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”

Hand1 downregulates <i>Ihh</i> and <i>Runx2</i> expression <i>in vivo</i>. by Lindsay E. Laurie (2504281)

“…(D) Expression of Ihh (a,b) and Runx2 (c,d) was detected by immunohistochemistry of E16.5 Wt (a) and <i>Hand1</i> mutant (b) femurs. …”

AS TR2-UBE3A mice had significant improvements in the Morris water maze. by Jennifer L. Daily (337749)

“…<p>(A) Escape latency to reach the platform during 5 days of training in Morris water maze. The only significant differences seen were an increase in latency for the AS TR2-GFP mice on day 3 and a decrease in latency for wildtype mice on day 4 compared to the other two groups (2-way ANOVA Bonferroni: Interaction [F(8,100) = 1.01, <i>P>0.05</i>]; Treatment [F(2,100) = 5.30, <i>P<0.05</i>]; Time [F(4,100) = 53.49, <i>P<0.0001</i>]; Matching [F(25,100) = 5.37, <i>P<0.0001</i>]). …”

Modeling and functional consequences of the p.Tyr313His <i>KISS1R</i> mutation. Panel A. by Frédéric Brioude (101781)

“…The lower panel shows the absence in ERK1/2 phosphorylation when cells were transfected with the vector containing Y313H-mutated KISS1R. C: positive control: WT KISS1R stimulated by kisspeptin after 5 minutes. …”

Adiponectin Modulates Oxidative Stress-Induced Autophagy in Cardiomyocytes by Eric E. Essick (435031)

“…H₂O₂ induced LC3I to LC3II conversion by a factor of 3.4±1.0 which was abrogated by pre-treatment with APN by 44.5±10%. …”

Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries by Pathadka, Swathi

“…Results: Consumption of systemic antifungal agents increased from 0.50 (in 2008) to 0.92 defined daily dose (DDD)/1000 inhabitants/day (in 2018), with a compound annual growth rate of 6.2%. …”
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Secreted Amyloid Precursor Protein β and Secreted Amyloid Precursor Protein α Induce Axon Outgrowth In Vitro through Egr1 Signaling Pathway by Stéphanie Chasseigneaux (231744)

“…</p> <h3>Methodology/Principal Findings</h3><p>Final concentrations of 50 to 150 nM bacterial recombinant sAPPα or sAPPβ added to primary neuronal cultures after 1 day in vitro decreased cell adhesion 24 hours later and primary dendrite length 96 hours later. 150 nM sAPPα and sAPPβ induced a similar increase of axon outgrowth, although this increase was already significant at 100 nM sAPPα. …”

DataSheet_1_E2F1 mediates competition, proliferation and response to cisplatin in cohabitating resistant and sensitive ovarian cancer cells.docx by Andres Valdivia (16546941)

“…Direct co-culture led to a decrease in the IC50 to platinum in the cisplatin-sensitive cells (5.92 µM to 2.79 µM for PE01, and from 2.05 µM to 1.51 µM for OVCAR5). …”

Data_Sheet_1_Large Gatherings? No, Thank You. Devaluation of Crowded Social Scenes During the COVID-19 Pandemic.pdf by Claudia Massaccesi (10898715)

“…Even people not directly affected by the virus itself were impacted in their physical and/or mental health, as well as in their financial security, by governmental lockdown measures. We investigated whether the combination of these events had changed people's appraisal of social scenes by testing 241 participants recruited mainly in Italy, Austria, and Germany in an online, preregistered study conducted about 50 days after the beginning of the COVID-19 outbreak in Europe. …”

Data_Sheet_1_Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies.pdf by Eli Hatchwell (8584452)

“…</p>Conclusion<p>For the first time, a PML genetic risk test can be implemented for screening patients taking or considering treatment with a PML-linked drug in order to decrease the incidence of PML and enable safer use of highly effective therapies used to treat their underlying disease.…”

Date palm wood flour/glass fibre reinforced hybrid composites of recycled polypropylene: Mechanical and thermal properties by AlMaadeed, Mariam A.

“…Morphological studies indicated that glass fiber has good adhesion with recycled PP supporting the improvement of the mechanical properties of hybrid composites with glass fiber addition. Addition of as little 5wt% glass fibre to wood flour reinforced RPP increases the tensile strength by about 18% relative to the wood flour reinforcement alone. …”
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Sequential action potentials vary in their amplitudes. by Na Chen (153323)

exRNAs from RV1B-infected cells activates innate RNA-sensing pathways to prevent <i>A</i>. <i>flavus</i>-induced lung inflammation. by Li She (2204779)

“…<b>B.</b> In contrast to WT mice, administration of RV1B RNA into TLR3^-/-MAVS^-/- mice did not significantly decrease the percentage and number of eosinophils in lungs after exposure to A. …”

Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations by Mathew J. Barber (251595)

“…<div><h3>Background</h3><p>Statins effectively lower total and plasma LDL-cholesterol, but the magnitude of decrease varies among individuals. To identify single nucleotide polymorphisms (SNPs) contributing to this variation, we performed a combined analysis of genome-wide association (GWA) results from three trials of statin efficacy.…”

Best tumor response (waterfall plot) in evaluable patients (n = 24). by Shailender Bhatia (116286)

Enzymatic activity of liver enzymes. by Torsten Diesinger (9159938)

“…<p><b>(a)</b> ALT is elevated by 71% and 50% compared to control groups 1 and 2. …”