Supporting datasets for all figures. by Matthew Drill (22258391)

“…This study examined the expression and function of P2X7R in a human glioblastoma cell line, U251. We used a pharmacological antagonist of P2X7R, AZ10606120, to inhibit receptor function and delineate downstream consequences of receptor inhibition. …”

The <i>baldrian</i> mutation interferes with embryonic cardiomyocyte proliferation in zebrafish. by Anja Bühler (2556937)

“…(G) Ventricular cardiomyocyte numbers at 48, 72 and 96 hpf, were significantly decreased in <i>bal</i> (48 hpf wt: 153.37 ± 39.91, n = 7 and <i>bal</i>: 94.71± 35.22, n = 8, p = 0.014; 72 hpf wt: 211.42 ± 28.81, n = 7 and <i>bal</i>: 122.85 ± 16.88, n = 7, p = 0.001; 96 hpf wt: 215.20 ± 48.35, n = 10 and <i>bal</i> 122.83 ± 22.83, n = 6, p = 0.001). …”

Impact of Environment and Social Gradient on <em>Leptospira</em> Infection in Urban Slums by Renato B. Reis (90436)

“…</p><h3>Methods and Findings</h3><p>We performed a community-based survey of 3,171 slum residents from Salvador, Brazil. …”

FoxP is required for dendritic growth and negatively regulates branching of type IV da neurons. by Anna Castells-Nobau (478493)

“…<i>Wt</i> (n = 5), <i>FoxP</i>^-/- (n = 5) controls (n = 5) and <i>UAS-FoxP</i>-<i>I2</i> (n = 5). …”

Reduced EPDC invasion correlates with deficient coronary vascular plexus development. by Andrew B. Harvey (21587431)

“…<b>(E, F)</b> Immunofluorescent stains marking vasculature (PECAM1, green), myocardium (MF20, blue), and SOX18 (red) suggest a decrease in SOX18 expression in the vasculature of <i>Wt1</i>^Cre; <i>Sox9</i>^fl/fl; <i>R26</i>^mG specimens compared to controls at E15.5. …”

Dorsal lateral striatum MSN CaMKII inhibition reduces excitatory transmission independently of changes in release probability. by Jason R. Klug (132807)

“…<p>(A) (Upper trace, black) NON EGFP (EAC3I-lacking) MSN PPR (50 ms ISI) example trace baseline (average of 20 sweeps, 0.05 Hz). …”

Hyperbaric oxygen therapy and comprehensive orthopedic treatment for incomplete traumatic spinal cord injury on the Qinghai-Tibet Plateau: study protocol for an open-label randomiz... by Jun Ma (4058161)

“…<div>Background: Apoptosis secondary to ischemia and hypoxia is the main cause of spinal cord dysfunction. Because of the decrease in atmospheric pressure, patients living on the Qinghai-Tibet Plateau are in a hypoxic environment, which is very unfavorable for the recovery of spinal cord injury. …”

The conserved motifs in the SBD of PluR and PauR are essential but not sufficient for ligand-binding specificity. by Sophie Brameyer (731567)

“…</sub> promoter activity approximately to 50% compared to PauR wild type. (<b>D</b>) DAR-sensing was decreased approximately about 70% in the PauR-Y90C/I113S derivative compared to PauR wild type (wt), however, PPYD-sensing could not gained. …”

Loss of the macrophage-TCR in the presence of functional T cells results in disorganized granulomas and CCL2 suppression in murine pulmonary tuberculosis. by Alexander W. Beham (196299)

“…<p>(<b>A</b>) TNF blockade decreases the number and size of macrophage clusters induced by <i>BCG</i> infection <i>in vitro</i>. …”

Activation of the UPR can override the inhibition of NF-κB by IKK inhibitors in cancer cells with elevated IKK activity. by Arvin B. Tam (124164)

“…A reduction in P-IκBα and increase in total IκBα were seen corresponding to a decrease in IKK activity. (E) SC514 does not affect UPR signalling. 786-0 cells were incubated with SC514 for 1 h (‘0’), then DTT was added up to 5 hrs. …”

Characterization of in vivo VSMCs in the aorta of <i>HtrA1</i>^<i>-/-</i> mouse and histological abnormalities of aortas isolated from <i>HtrA1</i>^<i>-/-</i> m... by Muthi Ikawati (5227451)

“…Two different batches of aortic extract from P5 <i>HtrA1</i>^<i>-/-</i> mice (KO-1 and KO-2), 52-wo wild type mice (WT-1 and WT-2), and <i>HtrA1</i>^<i>-/-</i> mice (KO-1 and KO-2) were analyzed. …”

Neosartorya glabra polygalacturonase produced from fruit peels as inducers has the potential for application in passion fruit and apple juices by Vanessa Elisa Pinheiro (10424390)

“…All these favourable enzymatic properties make the polygalacturonase attractive for potential uses in the industry of pectin-rich fruit juices, since the application of the crude extract to passion fruit (Passiflora edulis) juice caused an 80% reduction in viscosity and 75% decrease in light absorbance. In the processing of apple pulp juice (Malus domestica), there was a 50% reduction in viscosity and 78% decrease in light absorbance.…”

G2019S LRRK2 modulates Tf recycling in iPSC-derived human microglia. by Adamantios Mamais (302600)

“…The percentage of Tf vesicles proximal to the nucleus was significantly decreased with LPS treatment in WT but not in G2019S LRRK2 cells (E, F) (E: bin at 0.5 μm, two-tailed Student <i>t</i> test; Mann–Whitney <i>U</i> post hoc; **<i>P</i> = 0.0022; F: bin at 0.5 μm, two-tailed Student <i>t</i> test; Mann–Whitney <i>U</i> post hoc; NS). …”

Behavioral characterization of <i>Del-Dup</i> cohorts. by Thomas Arbogast (1783087)

“…Discrimination index was calculated as the ratio of time spent exploring the novel object vs the total time for object sniffing in the choice trial after a 3 h retention delay. The dashed line denotes a chance level of 50% (F_(3,43) = 3.081, <i>P</i> = 0.037; <i>Del/+</i> vs wt: <i>P</i> = 0.040). …”

The open field test. by Kaveri Arora (4033364)

Table_1_Stable carbon isotopes of dissolved inorganic carbon in the Western North Pacific Ocean: Proxy for water mixing and dynamics.pdf by Tiantian Ge (292883)

“…We found a strong ¹³C Suess Effect in the upper 2,000 m in the western NP Ocean, and δ¹³C-DIC at the surface (<50 m) has decreased by 0.60‰-0.85‰ since 1993. …”

The Cost-Effectiveness of Intermittent Preventive Treatment for Malaria in Infants in Sub-Saharan Africa by Lesong Conteh (231114)

Checkpoint, recombinational repair and mitochondrial functions are required for doxorubicin resistance in diploid yeast strains. by Tammy J. Westmoreland (38006)

“…Arrows indicate the direction of decreasing cell concentration. When compared to WT (row 1), defects in genes within the CCR4-NOT complex (rows 2–5) confer checkpoint adaptation functions and show intermediate sensitivity to doxorubicin. …”

DHPG-induced long-term depression is not dependent on protein synthesis or mammalian Target of Rapamycin in <i>Cyfip1</i> heterozygotes. by Ozlem Bozdagi (144573)

“…<p>(<b>A</b>) LTD was induced by DHPG (50 µM for 5 minutes, indicated by the short horizontal bar) in hippocampal slices from wildtype (Wt) and <i>Cyfip1</i> heterozygous (Het) mice. …”

Figure S1 - Microglial P2Y₁₂ Deficiency/Inhibition Protects against Brain Ischemia by Corey M. Webster (442040)

“…<p><b>Western blots of BV2 cells transfected with siRNA against P2Y₁₂ (P2Y₁₂ siRNA) or control siRNA (con siRNA) show approximately 50% decrease in protein.</b> Western blots of brain extracts from P2Y₁₂+/− versus wildtype (WT) mice show approximately 75% decrease in protein. β-actin is shown as a housekeeping protein. …”