Flavokawain B (FKB) down-regulates mRNA and protein expression of AR and AR target genes. by Xuesen Li (48046)

“…<p>(<b>A</b>).The protein expression of AR and PSA after indicated treatments for 16 hours or 5 µg/ml FKB for indicated period of times was analyzed by Western blot. α-Tubulin was detected as a loading control. …”

Supplementary Material for: Prognostic Accuracy of Mild Cognitive Impairment Subtypes at Different Cut-Off Levels by Göthlin M. (4092352)

“…For aMCI-md, sensitivity increased and specificity decreased when the cut-off was lowered from 2.0 to 1.5 and 1.0 SD. …”

Beta GAM modelling on the relationship between the proportion of remaining forest cover at the municipality level and socio-economic factors. by Raúl Abel Vaca (144236)

“…The trend is approximately linear on a log scale, so the gradient decreases along this part of the trajectory when the curve is plotted on a linear scale. …”

Analysis of slipped-DNA in native chromatin, and EM of IP'd DNA. by Michelle M. Axford (269322)

“…Also, see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003866#pgen.1003866.s005" target="_blank">Figure S5C</a> for a comparison of areas under each peak of the GeneScans before and after treatment. …”

FXS Early life flurothyl seizures on behavior and mTOR signaling by Joaquin Lugo (539236)

Data_Sheet_1_Aberrant amplitude of low-frequency fluctuations in different frequency bands and changes after one-night positive airway pressure treatment in severe obstructive slee... by Yuanfeng Sun (13277133)

“…In slow-4 frequency, there was significantly decreased ALFF in the right inferior temporal gyrus, and significantly increased ALFF in the left precuneus, right posterior cingulate gyrus and right median cingulate besides the slow-5 difference band showed. …”

DataSheet_1_Assessing phytoplankton community composition in the Atlantic Ocean from in situ and satellite observations.xlsx by Vanda Brotas (8487495)

DataSheet_3_Assessing phytoplankton community composition in the Atlantic Ocean from in situ and satellite observations.xlsx by Vanda Brotas (8487495)

Image_1_Assessing phytoplankton community composition in the Atlantic Ocean from in situ and satellite observations.jpeg by Vanda Brotas (8487495)

DataSheet_2_Assessing phytoplankton community composition in the Atlantic Ocean from in situ and satellite observations.xlsx by Vanda Brotas (8487495)

Fisetin reduces an experimental index of anxiety in Akita mice. by Pamela Maher (337300)

“…All data are mean ± SD of <i>n</i> = 5–7/group. *(<i>p</i><0.05) and **(<i>p</i><0.01) indicate significantly different from wild type or Akita alone as determined by ANOVA followed by Tukey's post test.…”

Effects of pretreatment with adrenergic receptor antagonists on ghrelin-induced suncus gastric contractions. by Anupom Mondal (397691)

“…<p>(A) Phentolamine (α adrenergic receptor antagonist; 10⁻⁵ M) significantly decreased contractions. …”

Quantitative observation of PAS-positive PVMs. by Atsuto Onoda (550095)

“…<p>A: The number of PAS-positive PVMs in each brain region (n = 5/group). …”

Table_1_Population Pharmacokinetics and Pharmacodynamics Modeling of Torasemide and Furosemide After Oral Repeated Administration in Healthy Dogs.pdf by Ludovic Pelligand (3955772)

“…The aim of this pharmacokinetic-pharmacodynamic (PK/PD) study was to define an optimally effective dosage regimen based on preclinical data. In a first study, 5 dogs received once-daily oral torasemide (0, 0.1, 0.2, 0.4, 0.8 mg/kg/day) for 14 days. …”

Table_2_Population Pharmacokinetics and Pharmacodynamics Modeling of Torasemide and Furosemide After Oral Repeated Administration in Healthy Dogs.pdf by Ludovic Pelligand (3955772)

“…The aim of this pharmacokinetic-pharmacodynamic (PK/PD) study was to define an optimally effective dosage regimen based on preclinical data. In a first study, 5 dogs received once-daily oral torasemide (0, 0.1, 0.2, 0.4, 0.8 mg/kg/day) for 14 days. …”

Changes in the total corneal refractive power after insertion of intrastromal rings in patients with keratoconus in short, medium and long term by Beatriz Rodríguez-Gutiérrez (15463936)

Anteriorly traveling Lfng stripes and segmentation-clock period. by Susan D. Hester (204004)

“…(<b>D</b>) For a uniform Wnt3a concentration of 0.5 nM, <b>cells</b>' segmentation-clocks oscillate in phase with a period of 90 min. …”

Task-related hemodynamic responses are modulated by reward and task engagement by Mariana M. B. Cardoso (6615959)

“…With higher rewards, animals appeared more task-engaged; task-related responses were more temporally precise at the task period (approximately 10–20 seconds) and modestly stronger. The 2–5 minute blocks of high-reward trials led to ramp-like decreases in mean local blood volume; these reversed with ramp-like increases during low reward. …”

Detection of relevant pharmacogenetic information through exome sequencing in oncology: Supplementary tables by Simon Verdez (13543819)

“…Materials</p> <p>& methods: To evaluate the interest of such pharmacogenetic information, the authors retrospectively</p> <p>analyzed genes known to have an impact on cancer therapy in a cohort of 445 solid cancers patients.</p> <p>Results: Six patients treated with 5-fluorouracil carrying one DPYD variant classified as 1A showed</p> <p>decreased drug mean clearance (p = 0.01). …”

DNA Methylation in the Human Cerebral Cortex Is Dynamically Regulated throughout the Life Span and Involves Differentiated Neurons by Kimberly D. Siegmund (193233)

“…Additionally, methylation studies on sorted nuclei provided evidence for bidirectional methylation events in cortical neurons during the transition from childhood to advanced age, as reflected by significant increases at 3, and a decrease at 1 of 10 loci. Furthermore, the DNMT3a <em>de novo</em> DNA methyl-transferase was expressed across all ages, including a subset of neurons residing in layers III and V of the mature cortex. …”