Table1_The impact of key monitoring policy on the usage of policy-related drugs in Hubei Province, China.DOCX by Xiaotong Wen (336520)

“…After the implementation of the KMRUD catalog policy, the monthly procurement volume of 10 policy-related drugs have a significant downward trend (p < 0.05), and 4 policy-related drugs have a significant upward trend (p < 0.05).…”

Translocation of HMGB1 into extranuclear and extracellular milieu in LPS/GalN-treatment. by Noriyuki Kuroda (545666)

“…GL-treatment strongly inhibits immunoreactivity of cytoplasmic and additional extracellular HMGB1 (<b>F</b>) and significantly retrieve a decrease of intranuclear immunoreactive products (<b>H</b>). …”

Chordoma preclinical models are insensitive to BAF complex inhibitor FHD-286, alone or in combination with gemcitabine by Chordoma Foundation (4391989)

“…CH22, UM-Chor1, U-CHCF365, and U-CH2 cell lines were plated in 100uL of (4:1) IMDM:RPMI 1640 + 10% FBS + 1% NEAA + 1% GlutaMAX. Cells were treated in triplicate with a 3-fold serial dilution of each drug with a top concentration of 5 uM to the lowest concentration of 0.762 nM. …”

Table 1_Cytokine profile, differential somatic cell count, and oxidative status of Italian Mediterranean buffalo milk affected by the temperature–humidity index.docx by Maria Giovanna Ciliberti (10718484)

“…The level of IL-4 was higher in the THI ≥ 76 class than in the ≤72 to <76 range. Data on DCC showed a decrease in the percentage of macrophages and lymphocytes as the THI increased from the ≤72 to <76 range to THI ≥ 76. …”

Table_1_Hypercapsule is the cornerstone of Klebsiella pneumoniae in inducing pyogenic liver abscess.docx by Dakang Hu (647924)

“…</p>Results<p>Differences were found between K. pneumoniae strains from PLA and non-PLA samples for virulence genes and factors, including metabolism genes (allS and peg-344), capsular polysaccharide (CPS)-synthesis channel gene (wzy-K1), CPS-regulating genes (p-rmpA, p-rmpA2, and c-rmpA), and siderophore genes (iucA and iroN). …”

Changes of the normalized volume V/V₀ in glioblastoma cell lines in response to sucrose- and inositol-substituted solutions of different osmolalities (LHS and RHS column... by Simon Memmel (518138)

“…Continuous curves in <i>A</i> show best least-square fits of the Lúcio-model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0087052#pone.0087052-Lcio1" target="_blank">[50]</a> to the data. …”

RbmB digests VPS <i>in vitro</i>. by Ranjuna Weerasekera (20371182)

“…Increasing amounts of RbmB show a decrease in the aggregates and increase in free Bap1, suggesting cleavage of VPS into small fragments. …”

DataSheet1_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.pdf by Xiaowan Wang (9704207)

“…Further studies showed that SQ treatment could significantly inhibit podocyte apoptosis in PHN rats and ADR-injured podocytes, and protein levels of Cleaved Caspase-3 or the ratio of Bax/Bcl-2 were significantly decreased with SQ treatment in vivo or in vitro. Moreover, we found that the nuclear factor erythroid 2–related factor-2/heme oxygenase 1 (Nrf2/HO-1) pathway mediated the anti-apoptosis effective of SQ in podocyte. …”

Table1_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.doc by Xiaowan Wang (9704207)

“…Further studies showed that SQ treatment could significantly inhibit podocyte apoptosis in PHN rats and ADR-injured podocytes, and protein levels of Cleaved Caspase-3 or the ratio of Bax/Bcl-2 were significantly decreased with SQ treatment in vivo or in vitro. Moreover, we found that the nuclear factor erythroid 2–related factor-2/heme oxygenase 1 (Nrf2/HO-1) pathway mediated the anti-apoptosis effective of SQ in podocyte. …”

Stage at diagnosis. by Tia S. Sutton (16985926)

“…We compared patients presenting before (pre-COVID) to those diagnosed after (COVID) March 1, 2020. …”

DataSheet_1_Cyprinid herpesvirus 2 infection changes microbiota and metabolites in the gibel carp (Carassius auratus gibelio) midgut.doc by Peng Chen (6514)

“…High-throughput sequencing demonstrated that the relative abundance of Aeromonas in the midgut increased dramatically while Cetobacterium decreased. Time-course analysis showed that the number of Aeromonas in the midgut of infected fish increased more than 1,000 times within 5 days post infection. …”

Patient demographics. by Tia S. Sutton (16985926)

“…We compared patients presenting before (pre-COVID) to those diagnosed after (COVID) March 1, 2020. …”

DataSheet6_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

“…Further studies showed that SQ treatment could significantly inhibit podocyte apoptosis in PHN rats and ADR-injured podocytes, and protein levels of Cleaved Caspase-3 or the ratio of Bax/Bcl-2 were significantly decreased with SQ treatment in vivo or in vitro. Moreover, we found that the nuclear factor erythroid 2–related factor-2/heme oxygenase 1 (Nrf2/HO-1) pathway mediated the anti-apoptosis effective of SQ in podocyte. …”

Data_Sheet_1_Comparative transcriptome analysis of MDBK cells reveals that BoIFN-γ augmented host immune responses to bovine herpesvirus 1 infection.docx by Bo Jiang (76119)

“…We subsequently investigated the effect of BoIFN-γ on BoHV-1 infection in Madin-Darby bovine kidney (MDBK) cells. …”

DataSheet3_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.zip by Xiaowan Wang (9704207)

“…Further studies showed that SQ treatment could significantly inhibit podocyte apoptosis in PHN rats and ADR-injured podocytes, and protein levels of Cleaved Caspase-3 or the ratio of Bax/Bcl-2 were significantly decreased with SQ treatment in vivo or in vitro. Moreover, we found that the nuclear factor erythroid 2–related factor-2/heme oxygenase 1 (Nrf2/HO-1) pathway mediated the anti-apoptosis effective of SQ in podocyte. …”

DataSheet7_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

“…Further studies showed that SQ treatment could significantly inhibit podocyte apoptosis in PHN rats and ADR-injured podocytes, and protein levels of Cleaved Caspase-3 or the ratio of Bax/Bcl-2 were significantly decreased with SQ treatment in vivo or in vitro. Moreover, we found that the nuclear factor erythroid 2–related factor-2/heme oxygenase 1 (Nrf2/HO-1) pathway mediated the anti-apoptosis effective of SQ in podocyte. …”

Presentation acuity & symptomatology. by Tia S. Sutton (16985926)

“…We compared patients presenting before (pre-COVID) to those diagnosed after (COVID) March 1, 2020. …”

DataSheet2_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

“…Further studies showed that SQ treatment could significantly inhibit podocyte apoptosis in PHN rats and ADR-injured podocytes, and protein levels of Cleaved Caspase-3 or the ratio of Bax/Bcl-2 were significantly decreased with SQ treatment in vivo or in vitro. Moreover, we found that the nuclear factor erythroid 2–related factor-2/heme oxygenase 1 (Nrf2/HO-1) pathway mediated the anti-apoptosis effective of SQ in podocyte. …”

The Soluble Guanylate Cyclase Activator BAY 58-2667 Protects against Morbidity and Mortality in Endotoxic Shock by Recoupling Organ Systems by Benjamin Vandendriessche (451155)

“…The resulting heme-free sGC can be reactivated by the heme- and nitric oxide (NO)-independent sGC activator BAY 58-2667 (Cinaciguat). We report that late (+8 h) post-treatment with BAY 58-2667 in a mouse model can protect against lethal endotoxic shock. …”

Circulating Microvesicles Are Elevated Acutely following Major Burns Injury and Associated with Clinical Severity by Kieran P. O’Dea (3391385)

“…All circulating microvesicle subpopulations were elevated in burns patients on day of admission (day 0) compared to healthy volunteers (leukocyte-microvesicles: 3.5-fold, <i>p</i> = 0.005; granulocyte-microvesicles: 12.8-fold, p<0.0001; monocyte-microvesicles: 20.4-fold, p<0.0001; endothelial- microvesicles: 9.6-fold, <i>p</i> = 0.01), but decreased significantly by day 2. …”