COMPARE-MS assay performance by Srinivasan Yegnasubramanian (27577)

“…The degree of capture of unmethylated DNA (untreated WBC DNA) in the presence of MBD2-MBD is less than or equal to the capture of DNA in the absence of MBD2-MBD or anti-His antibody, showing that capture of unmethylated DNA during the DNA capture step of COMPARE-MS is almost completely due to low amounts of non-specific binding to the protein G magnetic beads, as opposed to low-level binding of the MBD2-MBD to unmethylated DNA. () Plots showing the measured amount of methylated CGIs in M.SssI treated and untreated WBC genomic DNA versus the amount of input DNA after enriching for methylated DNA by the combination of methylation-sensitive restriction enzyme digestion and MBD2-MBD capture (COMPARE-MS) followed by real-time PCR. When 20–100 ng of input DNA are used, COMPARE-MS has a >5000-fold dynamic range, which is ∼500-fold higher than that of methylation-sensitive restriction enzyme used alone and ∼5- to 10-fold higher than that of MBD2-MBD capture used alone. () Plot showing measured output methylated CGIs as determined by COMPARE-MS when decreasing amounts of M.SssI-treated WBC DNA is diluted in 20 ng of untreated WBC genomic DNA. …”

Mutation-intolerant IDRs carry characteristic UniProt features compared to relatively tolerant IDRs. by Shehab S. Ahmed (12231721)

“…The horizontal dashed line at OR = 1.0 indicates no association between a residue type and a feature. To facilitate the visualization, minimum and maximum values of OR along the y-axis are set to 0.05 and 10.0, respectively. …”

The evolution of color space similarity among objects across CNN layers and the dependence of color space similarity on object form similarity. by JohnMark Taylor (8329326)

“…Results for random networks are averaged across 100 random initializations of the network. c. A schematic illustration of comparing color space similarity and object form similarity, using the same notations as those in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0253442#pone.0253442.g002" target="_blank">Fig 2A</a>. …”

Image 1_Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma conc... by Jun Yang (2084)

“…The 75 mg and 100 mg q12h groups showed a higher proportion of AUC_ss,24h within the therapeutic window. …”

Linking neural data with behavioral data in the EVA framework. by Quynh-Anh Nguyen (847240)

“…Averaged spike counts over <i>N</i>_<i>in</i> A1-neurons, , are normal-like distributed with means <i>m</i>_<i>DF</i> and standard deviation decreasing inversely with ; shown in gray (<i>DF</i> = 3), black (<i>DF</i> = 5) and light-gray (<i>DF</i> = 7) for <i>N</i>_<i>in</i> = 10 (upper panel) and <i>N</i>_<i>in</i> = 100 (lower panel). …”

Metabolic signature of aging and longevity in serum as per LC/MS eicosanoids profiling. by Sebastiano Collino (385873)

“…<p>Reported is median value in ng/100 µl serum among the three age groups. Blue denotes negative/decreased concentration, orange denotes positive/increased correlation, black denotes no changes. …”

Table_2_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.pdf by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”

DataSheet_2_Erythropoietin mediates re-programming of endotoxin-tolerant macrophages through PI3K/AKT signaling and protects mice against secondary infection.docx by Xue Zhang (166886)

“…Therefore, our findings indicate that EPO mediates the functional re-programming of endotoxin-tolerant macrophages. Mechanistically, we found that PI3K/AKT signaling contributed to EPO-mediated re-programming through upregulation of Irak3 and Wdr5 expression. …”

Table_1_Comparative Expression Analysis of Stress-Inducible Candidate Genes in Response to Cold and Drought in Tea Plant [Camellia sinensis (L.) Kuntze].XLSX by Lidiia S. Samarina (9911892)

“…Using qRT-PCR we revealed that 10 genes were significantly upregulated in response to both cold and drought in tea plant: HSP70, GST, SUS1, DHN1, BMY5, bHLH102, GR-RBP3, ICE1, GOLS1, and GOLS3. …”

Image_8_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.TIF by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”

Image_11_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.TIF by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”

Image_10_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.TIF by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”

Image_4_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.TIF by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”

Image_11_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.TIF by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”

Table_1_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.pdf by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”

Image_8_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.TIF by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”

DataSheet1_Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian cancer c... by István Kacsir (14520632)

“…The complexes containing [(η⁶-p-cymene)Ru(II)], [(η⁶-p-cymene)Os(II)] or [(η⁵-Cp*)Ir(III)] were biologically active unlike the complex containing [(η⁵-Cp*)Rh(III)]. …”

DATA for ''Widespread agrochemicals differentially affect zooplankton biomass and community structure.'' DOI: org/10.1002/eap.2423 by Marie-Pier Hébert (11128317)

“…We found that the biomass of major zooplankton groups differed in their sensitivity to pesticides: ≥0.3 mg/L glyphosate elicited long-lasting declines in rotifer communities, both pesticides impaired copepods (≥3 µg/L imidacloprid and ≥5.5 mg/L glyphosate), whereas some cladocerans were highly tolerant to pesticide contamination. …”

Table_2_Comparative Expression Analysis of Stress-Inducible Candidate Genes in Response to Cold and Drought in Tea Plant [Camellia sinensis (L.) Kuntze].XLSX by Lidiia S. Samarina (9911892)

“…Using qRT-PCR we revealed that 10 genes were significantly upregulated in response to both cold and drought in tea plant: HSP70, GST, SUS1, DHN1, BMY5, bHLH102, GR-RBP3, ICE1, GOLS1, and GOLS3. …”

Image_2_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.TIF by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”