Statistically significant correspondence between human psoriasis and mouse psoriasiform phenotypes: Analysis of ranked gene lists. by William R. Swindell (175427)

“…For any rank <i>N</i>, where <i>N</i> = 1, …, 5000, we isolated the top <i>N</i> human transcripts and identified orthologous mouse transcripts, and then determined whether these mouse transcripts overlapped significantly with the top <i>N</i> mouse transcripts increased or decreased in the (A) K5-Tie2 phenotype, (B) IMQ phenotype, (C) K14-AREG phenotype on ear skin, (D) K14-AREG phenotype on tail skin, (E) K5-Stat3C phenotype and (F) K5-TGFβ1 phenotype. …”

DataSheet_1_Fecal and serum metabolomic signatures and gut microbiota characteristics of allergic rhinitis mice model.docx by Zhen Chen (129176)

“…The colonic NF-κB protein was detected by Western Blot, and the colonic histological characteristics were observed by the H&E staining to evaluate inflammation of colon tissue. We analyzed the V3 and V4 regions of the 16S ribosomal DNA (rDNA) gene from the feces (colon contents) through 16S rDNA sequencing technology. …”

Presentation 1_Gender and age differences in the global burden of peptic ulcers: an analysis based on GBD data from 1990 to 2021.zip by Ruirui Tan (21188585)

“…</p>Results<p>The global number of PU cases increased from 2,570,413 in 1990 (95% CI: 2,161,831–2,997,880) to 2,854,370 in 2021 (95% CI: 2,438,231–3,264,252), representing a cumulative growth of 11.05%. However, the age-standardized incidence rate (ASIR) decreased from 57.14 (95% CI: 48.61–66.73) per 100,000 population in 1990 to 34.10 (95% CI: 29.13–38.97) per 100,000 population in 2021. …”

Chemical crosslinking of hSVCT1 in isolated oocyte membranes. by Rajendra Boggavarapu (214630)

“…<p>Western blot analysis of isolated oocyte membranes containing hSVCT1 incubated at different DST concentrations, i.e., 0, 100, 250, 500 and 1000 <i>µ</i>M. hSVCT1 monomer (<b>M</b>), dimer (<b>D</b>) and aggregate (<b>A</b>) bands are indicated. …”

EMT of ARPE-19 cells induced by TGF-β1. by Hui Li (32376)

“…Original magnifications 100× (A–D); 400× (E–T).</p>…”

Disease-specific morbidity and mortality in obese men versus randomly selected Danish young men. by Esther Zimmermann (198675)

“…</p><p>Cause of death information was not available in the 35 (and 65 censored) men who died before January 1 1970 and the 69 men who died after December 31, 2006, respectively, and were therefore not included in the cause of death analyses.</p><p>A total of 91 men died (and 100 men were censored) before January 1 1977, and where therefore not included in the incidence analyses.…”

TrkB expression. by Jin-Young Chung (390854)

“…<p>(<b>A</b>) Two forms of trkB are noted: full length form (140 kDa) and truncated form (90∼95 kDa). …”

BBR increases autophagic activity in cultured cells. by Wenxiao Jiang (777255)

“…<p><b>(A)</b> Western blotting of LC3B in HEK293 cells transfected with or without Htt and treated with BBR (0, 5, 25, 50, or 100 μM). …”

YC-1 Inhibits the Protein Expression of Various Pro-Angiogenic Molecules in VEGF-Stimulated Cells. by Michael DeNiro (297385)

“…In VEGF-stimulated/SN50-treated [20 µM], and VEGF stimulated/YC-1 treated [100 µM] cells, the protein expression levels were significantly decreased, as compared with SN50M and DMSO-treated cells. …”

Pre and post-treatment microPET/CT Study. by Albert J. Chang (389411)

“…RAD001 was then administered for 7 days and the scans repeated. There was a marked decreased in ⁶⁴Cu-NOTA-bevacizumab signal in the RAD001 compared to the vehicle control treated mouse. …”

The placenta releases sST2. by Ingrid Granne (343899)

“…C) Placental explants release sST2, secretion was increased by treatment with TNFα and IL-1β (100 ng/ml) and hypoxia-reperfusion injury, and was decreased under hypoxic conditions (n = 3).…”

METH preconditioning enhanced Akt but not JNK activation in response to 6-OHDA. by Amina El Ayadi (341955)

“…(A) METH decreased pAkt levels as shown for the 15 and 30 min time points. …”

Directional changes in temperature for North America, 1930–2004. by William B. Monahan (313511)

“…<p>(A) The contemporary environmental space showing grid cells that changed in a directional fashion with respect to minimum temperature of the coldest month or maximum temperature of the warmest month (colored grid cells, with directionality symbolized by arrows, matching legend in panel C); grid cells that did not experience directional change are not shown. …”

Tranilast inhibits mammosphere formation by mitoxantrone-selected MDA-MB-231 cells. by Gérald J. Prud'homme (238282)

“…<p>MDA-MB-231 mitoxantrone-selected cells were plated for mammosphere formation (1000 cells/well; 96-well plate, Cnt-27 medium) and grown with tranilast (100–400 µM), or a high concentration of either etoposide (40 µM) or paclitaxel (60 µM). …”

Sox2 expression in <i>Sox2-</i>siRNA and control <i>MF1</i>x<i>CD1</i> embryos. by Maria Keramari (237523)

“…<p>(<b>A</b>) Phase contrast images of day 5 incubator-control, <i>FFL</i>-siRNA, and <i>Sox2</i>-duplex-1, <i>-</i>2 and -3 siRNA embryos. …”

The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis by Shulan Pi (8562315)

“…<i>In vivo</i>, inhibition of the P2RY12 receptor promoted autophagy of VSMCs through PI3K-AKT-MTOR in advanced atherosclerosis in <i>apoe^-/-</i> mice, which could be impeded by an autophagy inhibitor (chloroquine). Therefore, we conclude that activation of the P2RY12 receptor decreases cholesterol efflux and promotes VSMC-derived foam cell formation by blocking autophagy in advanced atherosclerosis. …”

<strong>Supplementary Figure 1.</strong>  by Muhammad Aslam (6598628)

“…Control organoids (on left) were present as thick-walled structures with few surface buds. A wide range of sizes and shapes were seen under all conditions. …”

FPE reduced oxidative stress in experimental diabetic mice. by Wei Yu (43094)

“…<p>A: FPE effected SOD activity in heart tissue. SOD: superoxide dismutase. …”

IL-2 induction of NKp44 expression on CD56^bright NK cells is inhibited by mycobacteria. by Damien Portevin (228474)

“…<p>A) FACS plot analysis of NKp44 expression from NK cells cultured in the presence or the absence of IL-2 (100U/ml) and or <i>M. bovis</i> BCG (MOI 1:5) for 5 days. …”

The sensitivity of small-world networks to size and average degree changes depends on rewiring probability. by Bernadette C. M. van Wijk (238836)

“…<b>A</b>: Effects of changes in the number of nodes (<i>N</i>) while keeping the average degree constant (<i>k</i> = 10). …”