Successful restoration of knee extension after transferring of the anterior branch of the obturator nerve: a case study by Mohammadreza Emamhadi (10176503)

“…</p> <p><b>Methods:</b> We describe a 27-year-old male who had quadriceps femoris muscle paralysis after surgical evacuation for retroperitoneal hematoma five months ago. …”

Glasslike Membrane Protein Diffusion in a Crowded Membrane by Ignacio Munguira (1434316)

Error budget for the peak energy of all the spectral profiles of Ti Kβ that go into the final energy determination by C T Chantler (557430)

“…The peak energy of the titanium Kβ spectral profile is found to be 4931.966 ± 0.022 eV prior to instrumental broadening. This 4.5 ppm result decreases the uncertainty over the past literature by a factor of 2.6 and is 2.4 standard deviations from the previous standard. …”

Docking of LDCVs Is Modulated by Lower Intracellular [Ca²⁺] than Priming by Mathias Pasche (74950)

“…The parameters that reflect docking, i.e. axial mobility and the fraction of LDCVs residing at the plasma membrane for less than 5 seconds, were strongly decreased at a free [Ca²⁺]_i of 500 nM. …”

Reconciling a Kinetic Model for Dimerization of the EGFR Using Single-Molecule Tracking in Living Cells by Kiwook Kim (756439)

High-Throughput Identification of Chemical Inhibitors of <em>E. coli</em> Group 2 Capsule Biogenesis as Anti-Virulence Agents by Carlos C. Goller (245570)

“…Components of assembly and export are highly conserved among the major K antigen capsular types associated with UTI-causing <em>E. coli</em> and are distinct from the capsule biogenesis machinery of many commensal <em>E. coli</em>, making these attractive therapeutic targets. We conducted a screen for anti-capsular small molecules and identified an agent designated “C7” that blocks the production of K1 and K5 capsules, unrelated polysaccharide types among the Group 2–3 capsules. …”

Data_Sheet_2_Rewiring of Gene Expression in Pseudomonas aeruginosa During Diauxic Growth Reveals an Indirect Regulation of the MexGHI-OpmD Efflux Pump by Hfq.pdf by Marlena Rozner (12911555)

“…As Hfq function is impeded by the RNA CrcZ upon relief of CCR, and Hfq is known to impact antibiotic susceptibility in P. aeruginosa, emphasis was laid on links between CCR and antibiotic susceptibility. To this end, we show that the mexGHI-opmD operon encoding an efflux pump for the antibiotic norfloxacin and the virulence factor 5-Methyl-phenazine is upregulated after alleviation of CCR, resulting in a decreased susceptibility to the antibiotic norfloxacin. …”

Effect of inhibitors of caveolae- and clathrin-dependent endocytosis on TGFBIp internalization. by Seung-il Choi (50895)

“…TGFBIp was internalized in corneal fibroblasts (lane 5) but not in 3T3 MEF CAV-1 KO cell lines (lanes 6 and 8). …”

Reduced 14-3-3 θ association with centrosomal proteins, centrin and Plk1, during HIV-1 infection-induced G,M arrest by Diane L Bolton (92098)

“…(A) Jurkat cells were mock-infected (-) or infected with NL4-3derivatives encoding wild-type Vif and Vpr (wt), deleted Vpr (r-), deleted Vif (f-), or double deletion of Vpr and Vif (fr-) at an MOI of 1.5. …”

Activated ILC2s induce ASM proliferation <i>in vitro</i> in an HMGB1-dependent manner. by Zhixuan Loh (9115796)

“…<p>(a-b) Primary ASM cells were isolated from naïve WT neonatal mice and cultured with ILC2s (purified from the lungs of IRF7^-/- mice at 10 dpi) in the presence of various stimuli as indicated. …”

Actin oscillations depend on the extent and timing of Gβ sequestration. by Oliver Hoeller (2148580)

“…To achieve stable, intermediate levels of Gβ sequestration, cells were cotreated with 300 nM rapamycin and 0, 5, 10, 20 or 40 μM FK506, a competitive inhibitor of rapamycin. …”

Cort expression leads to proteasome-mediated degradation of Mtrm in cell culture. by Zachary J. Whitfield (453399)

“…Only wild-type Cort leads to decreased levels of tagged Mtrm protein. The <i>RH65</i> mutation results in a premature stop codon in Cort. …”

Programmed Cell Death Progresses Differentially in Epidermal and Mesophyll Cells of Lily Petals by Hiroko Mochizuki-Kawai (830866)

“…Before visible signs of senescence could be observed, we found signs of PCD, including DNA degradation and decreased protein content in mesophyll cells only. …”

DataSheet1_Deficiencies in the Recognition and Reporting of Chronic Kidney Disease in Patients With Type 2 Diabetes Mellitus; A Hungarian Nationwide Analysis.PDF by Erzsébet Ladányi (16897194)

“…The annual incidence of T2DM and incidence rates of CKD in T2DM decreased in 2017–2020 (p < 0.001). The annual prevalence of T2DM increased (p < 0.01), the prevalence rates of CKD in T2DM were low and decreased from 9.8% to 6.5% in 2016–2020 (p < 0.001).…”

Table_1_Synergistic Modulations of Large-Scale Synoptic Patterns and Local-Scale Urbanization Effects on Summer Rainfall in South China.DOCX by Minxuan Zhang (11829497)

“…<p>Using the ERA5 (the fifth major global reanalysis produced by the European Centre for Medium-Range Weather Forecasts) data and the T-PCA (Principal Component Analysis in T-mode) objective classification method to classify the 850-hPa geopotential height, we summarize four conceptual models of large-scale synoptic weather types over East Asia. …”

<em>Nigella sativa</em> (Black Cumin) Seed Extract Alleviates Symptoms of Allergic Diarrhea in Mice, Involving Opioid Receptors by Swantje C. Duncker (154707)

“…DAMGO, in contrast, had no effect on mast cell parameters but decreased IFNγ, IL-4, IL-5, and IL-10 concentration after <em>ex vivo</em> re-stimulation of mesenteric lymphocytes. …”

DataSheet1_Mechanisms of Arrhythmogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant I79N.pdf by Sanam Shafaattalab (8299433)

“…These changes in Ca²⁺ handling resulted in beat-to-beat instability and triangulation of the cardiac action potential, which are predictors of arrhythmia risk. While wild-type (WT) hiPSC-CMs were accurately entrained to frequencies of at least 150 bpm, the I79N hiPSC-CMs demonstrated clear patterns of alternans for both V_m and Ca²⁺ transients at frequencies >75 bpm. …”

Supplementary Material for: Hypofractionated Radiotherapy for Anaplastic Thyroid Carcinoma: 15 Years of Experience in a Single Institution by Takahashi N. (4478392)

“…<b><i>Methods:</i></b> Thirty-three patients who received radiotherapy for ATC between January 2000 and December 2014 were retrospectively included. We defined hypofractionated radiotherapy as a single dose ≥5 Gy. …”

Table_1_Application of Strategic Transport Model and Google Maps to Develop Better Clot Retrieval Stroke Service.DOCX by Atousa Tajaddini (6893573)

“…Futures modeling using VITM found that this proportion decreases to 82% after 5 years and 80% after 10 years. …”

Data Sheet 2_Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.pdf by Samira Rastgoo (15252703)

“…</p>Results<p>After the intervention, supplementation with D5N and D5 significantly downregulated p16, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) expression and decreased SA-β-gal activity compared to the D1 group. …”