Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…C−C elimination from complexes with the common d⁶ six-coordinate configuration generally proceeds via prior ligand loss, which greatly complicates any attempt to directly measure the rates of the specific elimination step. We report the synthesis of a series of five-coordinate d⁶ iridium complexes, (^tBuPCP)Ir(R)(R′), where R and R′ are Me, Ph, and (phenyl-substituted) vinyl and alkynyl groups. …”

Image_3_Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice.TIF by Haixia Kuang (5864108)

“…We found that the spiking frequency, excitatory inputs, and sag ratio were decreased in L5 pyramidal neurons of p53KO mice. …”

Image_1_Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice.TIF by Haixia Kuang (5864108)

“…We found that the spiking frequency, excitatory inputs, and sag ratio were decreased in L5 pyramidal neurons of p53KO mice. …”

Image_4_Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice.TIF by Haixia Kuang (5864108)

“…We found that the spiking frequency, excitatory inputs, and sag ratio were decreased in L5 pyramidal neurons of p53KO mice. …”

Image_2_Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice.TIF by Haixia Kuang (5864108)

“…We found that the spiking frequency, excitatory inputs, and sag ratio were decreased in L5 pyramidal neurons of p53KO mice. …”

ITC analysis of ligand binding. by Jenni Leppiniemi (166920)

“…In order to prove that the intrinsic Brad-tag decreases the affinity towards biotin, wt bradavidin was also titrated with biotin (4). …”

Expression of thrombin receptors, α_IIbβ₃ and P-selectin in PP1cγ^−/− platelets. by Francisca C. Gushiken (368549)

“…Results are expressed as ±SEM of 5–6 experiments. Compared to thrombin stimulated WT platelets, the decreased binding of JON/A antibody to PP1cγ^−/− platelets was significant at *p = 0.003.…”

DataSheet_1_Nationwide Trends of Pediatric Obesity and BMI z-Score From 2017-2021 in China: Comparable Findings From Real-World Mobile- and Hospital-Based Data.docx by Yan Yang (33204)

“…The trend of obesity prevalence remained stable with slight decrease, but COVID-19 lockdown caused a significant increase of 1.86% in 2020. …”

Functional Characterization of FLT3 Receptor Signaling Deregulation in Acute Myeloid Leukemia by Single Cell Network Profiling (SCNP) by David B. Rosen (104278)

“…Specifically, increased basal p-Stat5 levels, decreased FLT3L induced activation of the PI3K and Ras/Raf/Erk pathways, decreased IL-27 induced activation of the Jak/Stat pathway, and heightened apoptotic responses to agents inducing DNA damage were observed in FLT3-ITD AML samples. …”

Chile’s 2014 sugar-sweetened beverage tax and changes in prices and purchases of sugar-sweetened beverages: An observational study in an urban environment by Juan Carlos Caro (4707607)

“…The volume of household purchases of L-SSBs increased 10.7% (95% CI 7.5%–13.9%), while that of untaxed beverage purchases decreased by 3.1% (95% CI −5.1%–−1.1%). …”

Replacement of chicken skin with canola oil in chicken nuggets by Sandra Tiemi Seó (16453032)

“…The pH values ranged from 6.62 to 6.86, as an effect of frying, there was an increase in lipid content with increasing levels of substitution (T0-raw: 5.36% and fried: 12.11%; T100-raw: 7.93% and fried: 15.43%) and a decrease in moisture content in relation to the raw sample. …”

Production and characterization of gypsum-based composites reinforced with cocoa agroindustry waste particles by Maria Cecíllia Ramos de Araújo Veloso (10472934)

“…It was found that there were improvements in physical properties with the addition of reinforcement making the material lighter, given the reduction in density (1190.69 to 1138.92 kg/m³), ??and providing a decrease in hygroscopicity, with moisture levels decreasing from 7.74 to 4.01% and water absorption decreasing from 18.37 to 5.28%. …”

Unacetylable Shs1 mutants display defects in bud morphology and septin localization. by Leslie Mitchell (203047)

“…<p>(<b>A</b>) Shs1-HA₃ exhibits decreased acetylation <i>in vivo</i>. …”

MSc Dissertation Figures by Bianca Diedericks (17370739)

“…</p><p dir="ltr">Figure 3: Euclea natalensis: (A) Tree, (B) Fruits, and (C) Flowers.</p><p dir="ltr">Figure 4: Chemical structure: (A) 7-Methyljuglone and (B) Diospyrin</p><p dir="ltr">Figure 5: The postulated mechanism of action of 7-methyljuglone which will disrupt the electron transport chain and therefore decrease or stop the electron flow in the bacterium.…”

REREa, Fat3 and Dchs2 are required for cartilage stacking and polarity. by Pierre Le Pabic (603954)

“…(<b>I</b>–<b>J</b>): Fat3-MO injection decreases Fat3 protein levels (loss of green in I) in comparison to WT levels (J). …”

<i>In cellulo</i> Evaluation of Phototransformation Quantum Yields in Fluorescent Proteins Used As Markers for Single-Molecule Localization Microscopy by Sergiy Avilov (575857)

“…To this aim, we developed a data processing strategy based on the clustering optimization procedure proposed by Lee et al (PNAS 109, 17436–17441, 2012). …”

Data_Sheet_1_Present and future distribution of Faidherbia albida in Cabo Verde as revealed by climatic modelling and LULC analysis.PDF by Danilson Varela (14799583)

“…On average, the predicted suitable habitat for future distributions gradually decreases by 2080 under both scenarios compared with the current, with a smaller effect of RCP4.5 than of RCP8.5. …”