Mathematical Modeling Reveals Kinetics of Lymphocyte Recirculation in the Whole Organism by Vitaly V. Ganusov (142019)

“…The model also predicts a relatively short average residence time of TDLs in the spleen (2.5 hours) and a longer average residence time of TDLs in major lymph nodes and Peyer's patches (10 hours). …”

Distinct CLP migratory groups persist under low serum conditions. by Joël Beyeler (652358)

“…<p>The graphs show the RWC in scratch wound assays at 24 h in 0.3% FCS/DMEM (*p<0.05, **p<0.01, ***p<0.001). (A) Despite a general decrease of the RWC, “fast” and “intermediate” CLP groups could still be distinguished under low-serum conditions. …”

Infected cells in the neighbourhood of CD8+ T cells secreting non-lytic factors. by Nafisa-Katrin Seich al Basatena (201133)

“…We tracked the proportion of wild type- and variant-infected cells in the immediate neighbourhood (radius = 1, i.e. 26 neighbours) of 5,425 secreting CD8+ T cells. …”

Data_Sheet_1_Little Impact of NaCl Reduction in Swiss-Type Cheese.docx by Valérie Gagnaire (783586)

“…Casein hydrolysis in vitro was similar or higher at pH 5.2, i.e., cheese pH, compared to pH 7.5, and slightly decreased at the highest salt concentrations (3.0 and 4.4%). …”

Table 1_Trends in the disease burden of maternal sepsis and other maternal infections attributable to iron deficiency from 1990 to 2021 and its projection until 2050.docx by Chunfeng Zhu (327990)

“…The ASMR and age-standardized DALY rate of MSMIs attributable to iron deficiency were negatively correlated with SDI. Projections indicated a continued decrease in the burden of MSMIs attributable to iron deficiency by 2050.…”

Do psychosocial factors modify the negative association between disability and life satisfaction in old age? by Thomas Puvill (726017)

“…The impact of (I)ADL disabilities on life satisfaction was strongest at age 50 and gradually decreased with increasing age (p trend < 0.001). Mental health explained more variance; 5.75% for depressive symptoms and 2.50% for loneliness and for social resources this ranged from 0.09% to 0.47% (all p < 0.001). …”

Fatigue indices and perceived exertion highlight ergometer specificity for repeated sprint ability testing by Hugo Kerhervé (618369)

“…During recovery, RPE was consistently higher on NMT at 1, 3 and 5 min postexercise compared to CE. These findings indicate that RSA performed on NMT induces greater fatigue and physiological load than CE, which originated in the lower resistive torque typically used on NMT compared to CE, resulting in a frontloaded power output profile from the greater acceleration and cadence. …”

Expression of <i>LINC03045</i> in patient glioma samples from The Cancer Genome Atlas (TCGA) and The Genotype-Tissue Expression (GTEx) project. by Kathleen Tsung (18794564)

“…Cohorts divided into quartiles show a significant decrease in survival with increased expression levels in LGG (p = 0.002), but not GBM (p = 0.40). …”

Hepatitis C Virus Translation Preferentially Depends on Active RNA Replication by Helene Minyi Liu (139939)

“…When the movement of HCV RNA from the site of RNA synthesis to the Golgi complex was blocked by nocodazole, an inhibitor of ER-Golgi transport, HCV protein translation was surprisingly enhanced, suggesting that the translation of viral proteins occurred near the site of RNA synthesis. We also found that the translation of HCV proteins was dependent on active RNA synthesis: inhibition of viral RNA synthesis by an NS5B inhibitor resulted in decreased HCV viral protein synthesis even when the total amount of intracellular HCV RNA remained unchanged. …”

Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies by Gleb Kichaev (652009)

“…We validate our findings using a large scale meta-analysis of four blood lipids traits and find that the relative probability for causality is increased for variants in exons and transcription start sites and decreased in repressed genomic regions at the risk loci of these traits. …”

Inner ear pathology in MPS IIIB mice at 30 wks. by Coy D. Heldermon (78170)

“…Plot of the number of hair cell profiles versus neuronal density, as seen in radial view in the lower base for 5 MPS IIIB and 5 WT mice at 30 wks. Differences in hair cell numbers by genotype are highly significant (t-test, p<.001). …”

Axon misguidance phenotypes in vivo occur where the Shh gradient is shallow. by Tyler F. W. Sloan (715369)

“…<p><b>(A)</b> Mouse e9.5 (left) and e10.5 (middle and right) spinal cord cross-sections immunostained for Shh. …”

DataSheet_1_The potential role of exosomal miRNAs and membrane proteins in acute HIV-infected people.docx by Xin Li (51274)

“…In this study, exosomal miRNAs sequencing and mass cytometry were used to identify differential exosomal miRNAs and membrane proteins that participate in the pathogenesis of TPs and RPs. We discovered that miR-144-5p, miR-1180-3p, miR-451a, miR-362-5p, and miR-625-5p are associated with the TPs and miR-362-5p with the RPs. …”

Abbreviations of variables. by Chuin-Shee Shang (244530)

“…Because that the number of indigenous cases per area during a bi-week in low transmission season is mostly zero, we calculate the ratio by adding 0.5 to both the denominator and numerator.…”

Swimming endurance training protocol. by Vítor S. Fernandes (21262991)

“…<i>Mib1</i>^<i>flox</i><i>;Tnnt2</i>^<i>Cre</i> cardiomyocytes also showed decreases in outward K⁺ peak currents and currents at the end of depolarizing pulses at potentials ≥−10 mV and ≥−20 mV, respectively, and this was accompanied by a lower charge density at ≥−20 mV. …”

ChIP-seq findings for <i>Nr2f1</i>, <i>Nr2f2</i>, <i>Meis1</i>, and <i>Meis2</i> identify RARE enhancers in gene families. by Marie Berenguer (8856509)

“…<p>(A-B) <i>Nr2f1</i> and <i>Nr2f2</i> have RA-regulated peaks (red bars) for both H3K27ac (decreased) and H3K27me3 (increased) when RA is lost in E8.5 trunk from <i>Aldh1a2</i>-/- (KO) compared with WT. …”

Thermal denaturation. by Devesh Kishore (150318)

“…(E) Represents residual enzymatic activity as a function of heat denaturation for 5 min, at respective temperatures.…”

Effects of transplanted ES and iPS cells on cardiac fibrosis. by Hilda Merino (591759)

“…DOX-MI and DOX-MI+CC; n = 5–7. Bottom middle histogram (<b>L</b>) shows quantitative analysis of vascular fibrosis over total vascular area with a significant decrease in vascular fibrosis percentage in DOX-MI+ES and DOX-MI+iPS groups when compared with DOX-MI and DOX-MI+CC. …”

Polyunsaturated fatty acid synthesis de novo is required for calcium release in vascular smooth muscle by Nicola Irvine (591917)

“…<p>Previous studies show that inhibition of delta-5 desaturase and delta-6 causes a<br>decrease in phenylepherine (PE)- induced vasoconstriction in human femoral artery,<br>and in rat aorta and mesenteric arteries. …”

Comparison of substrate metabolism in brown and white preadipocytes and adipocytes. by Barry R. Bochner (226699)

“…<p>Normalized optical-density scores representing nutrient metabolism, showing the greatest differences between white fat (top) and brown fat (bottom) cells in either an undifferentiated (gray bars) or differentiated (black bars) state. Included are a) wells that cause no change (1, negative control), b) nutrients that are high in brown preadipocytes and decrease upon differentiation (2, α-D-glucose-1-phosphate; 3, D-glucose-6-phosphate; 4, D-fructose-6-phosphate; 5, glycogen), c) a similarly behaved nutrient that is high in white fat (6, hexanoic acid), d) nutrients that decrease during differentiation of both cell types (7, dextrin; 8, butyric acid), and e) nutrients that increase upon white fat differentiation (9, L-leucine; 10, Leu-Leu; 11, succinamic acid, 12. acetoacetic acid). …”