Data_Sheet_1_Mitochondrial Deficits With Neural and Social Damage in Early-Stage Alzheimer’s Disease Model Mice.docx by Afzal Misrani (10258750)

“…We observed increased levels of mitochondrial fission protein, Drp1, and decreased levels of ATP synthase subunit, ATP5A, leading to abnormal mitochondrial morphology, increased oxidative stress, glial activation, apoptosis, and altered neuronal morphology as early as 4∼5 months of age in APP/PS1 mice. …”

Evolution in the profile of thyroid cancer cases treated in an oncology reference service: what changed in the last 20 years by Renan Bezerra Lira (7032854)

“…Neck dissection associated with thyroidectomy was done in 158 patients (19.5%). We observed a predominance of tumors classified as T1 in 602 (74.6%) patients. …”

Phosphorylated IκBα Predicts Poor Prognosis in Activated B-Cell Lymphoma and Its Inhibition with Thymoquinone Induces Apoptosis via ROS Release by Azhar R. Hussain (154380)

“…Additionally, TQ treatment also caused up-regulation of death receptor 5 (DR5), however, up-regulation of DR5 did not play a role in TQ-induced apoptosis. …”

Data_Sheet_1_Talent Selection Strategies and Relationship With Success in European Basketball National Team Programs.PDF by Anton Kalén (5038625)

“…On average, 15.6 ± 2.0 male and 12.4 ± 1.8 female players were selected per generation. Over a third of the NTs consistently selected a higher or lower number of players than the average, with a difference of 8.1 players (95% CI [5.8, 10.8]) for men and 7.6 players (95% CI [5.4, 10.0]) for women between the countries with the highest and lowest average. …”

γ-Synuclein Antibodies Have Neuroprotective Potential on Neuroretinal Cells via Proteins of the Mitochondrial Apoptosis Pathway by Corina Wilding (529868)

“…We found a protective effect of γ-synuclein antibody resulting in an increased viability (up to 15%) and decreased reactive oxygen species levels (up to −12%) of glutamate and oxidative stressed RGC-5. …”

Nucleo-Cytoplasmic Localization Domains Regulate Krüppel-Like Factor 6 (KLF6) Protein Stability and Tumor Suppressor Function by Estefanía Rodríguez (242231)

“…</p><h3>Methodology/Principal Findings</h3><p>In this study, we demonstrate using EGFP fusion constructs that KLF6/KLF6-SV1 nucleo-cytoplasmic transport is not regulated by the 5′ basic region but activated by a novel NLS encoded within the ZF domain, and a nuclear export signal (NES) located in the first 16 amino acids of the shared N-terminus sequence. …”

The Tree GSPF Level Tree Chronogram of Poison Frogs with Known Taxonomic Diversity (i.e., Numbers within Parentheses) and Significant Diversification Rate Changes for Nodes or Line... by Juan C Santos (267336)

“…The significant increases indicated by a star next to nodes 2 and 9 might be dependent on deeper nodes (i.e., 1 and 5, respectively) and produced by a “trickle-down effect” (see “Lineage Diversification” in Results).…”

The effect of ribavirin (Rib) and guanosine (Gua) on HCV infectious progeny production and intracellular viral RNA and nucleotide pools. by Ana M. Ortega-Prieto (446894)

“…<p>(a) Huh-7.5 reporter cells were infected with HCVp0 at a initial MOI of 0.1–0.2 TCID₅₀/cell, in the absence or presence of the Rib and Gua concentrations indicated in the upper box. …”

DataSheet_1_Complement Factor H Family Proteins Modulate Monocyte and Neutrophil Granulocyte Functions.pdf by Éva Kárpáti (9129206)

“…We found that, similar to FH, the other factor H family proteins FHL-1, FHR-1 and FHR-5, as well as the recombinant mini-FH, are able to bind to both monocytes and neutrophils. …”

DataSheet2_Epigenetic Modifier Supplementation Improves Mitochondrial Respiration and Growth Rates and Alters DNA Methylation of Bovine Embryonic Fibroblast Cells Cultured in Diver... by Matthew S. Crouse (11446869)

“…Total cell growth was greatest in High ×10 and mitochondrial maximal respiration, and reserve capacity was greatest (p < 0.01) for High ×2.5 and ×10 compared with all other treatments. In Low cells, the total growth rate, mitochondrial maximal respiration, and reserve capacity increased quadratically to 2.5 and ×5 and decreased to control levels at ×10. …”

DataSheet1_Epigenetic Modifier Supplementation Improves Mitochondrial Respiration and Growth Rates and Alters DNA Methylation of Bovine Embryonic Fibroblast Cells Cultured in Diver... by Matthew S. Crouse (11446869)

“…Total cell growth was greatest in High ×10 and mitochondrial maximal respiration, and reserve capacity was greatest (p < 0.01) for High ×2.5 and ×10 compared with all other treatments. In Low cells, the total growth rate, mitochondrial maximal respiration, and reserve capacity increased quadratically to 2.5 and ×5 and decreased to control levels at ×10. …”

DataSheet3_Epigenetic Modifier Supplementation Improves Mitochondrial Respiration and Growth Rates and Alters DNA Methylation of Bovine Embryonic Fibroblast Cells Cultured in Diver... by Matthew S. Crouse (11446869)

“…Total cell growth was greatest in High ×10 and mitochondrial maximal respiration, and reserve capacity was greatest (p < 0.01) for High ×2.5 and ×10 compared with all other treatments. In Low cells, the total growth rate, mitochondrial maximal respiration, and reserve capacity increased quadratically to 2.5 and ×5 and decreased to control levels at ×10. …”

Image1_Epigenetic Modifier Supplementation Improves Mitochondrial Respiration and Growth Rates and Alters DNA Methylation of Bovine Embryonic Fibroblast Cells Cultured in Divergent... by Matthew S. Crouse (11446869)

“…Total cell growth was greatest in High ×10 and mitochondrial maximal respiration, and reserve capacity was greatest (p < 0.01) for High ×2.5 and ×10 compared with all other treatments. In Low cells, the total growth rate, mitochondrial maximal respiration, and reserve capacity increased quadratically to 2.5 and ×5 and decreased to control levels at ×10. …”

Western blot analysis of expression and phosphorylation of wild-type and mutated FGFR4 and its downstream target, STAT3, after treatment with 0, 200, and 800 nM concentrations of p... by Samuel Q. Li (466819)

“…(C-D) Western blot shows a dose-dependent decrease in STAT3 phosphorylation after treatment with ponatinib for three fusion-positive (RH4, RH5, and RH41) and one fusion-negative (CTR) RMS cell lines as well as the two RMS772 cell lines expressing the FGFR4 mutations N535K and V550E.…”

Supplementary Figures S1-S11 from The Novel, Small-Molecule DNA Methylation Inhibitor SGI-110 as an Ovarian Cancer Chemosensitizer by Fang Fang (38179)

“…(A). QD5 treatment. (D). biweekly treatment. Data shown represent means {plus minus} S.E.M. from 5 tumors. …”

Arginase-2 mutation reduces muscle fibrosis. by Michelle Wehling-Henricks (342479)

“…Arginase-2 mutation reduced fibrosis in diaphragm, longissimus dorsi (LD) and heart of wild-type mice. Sol  =  soleus. n = 5 animals per group. (B-F) The concentration of macrophages, eosinophils, CD4+ cells, CD8+ cells and neutrophils in muscles were not affected by arginase-2 mutation. # indicates statistical significance at p<0.05 as compared to C57; ̂ indicates statistical significance at p<0.05 as compared to mdx; * indicates statistical significance at p<0.05 as compared to A2ko/wt. n = 7 animals per group. …”

Temporal and Spatial Expression Patterns of miR169 gene and <i>NF-YA10</i> in response to Pi availability. by Marco Antonio Leyva-González (123692)

“…<p>(<b>A</b>) Northern blot analysis of miR169 in response to Pi availability (+P, 1 mM and −P, 5 µM) in 8 and 14-day-old <i>hen 1-1</i> and in WT seedlings. miR156 probe was used as a control to confirm that mature microRNAs in general have decreased levels or are absent in <i>hen1-1</i>. …”

Relative expression of pTten, Akt1 and Akt2 genes in S334ter-4 Rho retinas. by Vishal M. Shinde (178347)

“…Subsequently, the expression of this gene decreased to WT levels. In contrast, the expression of the Akt1 and 2 genes increased after P12 and reached a peak on P15. …”

Intravenous MSC treatment prevented white matter injury and reduced electrographic seizure activity after global HI. by Reint K. Jellema (127097)

“…(<b>B</b>) Global HI caused a significant decrease in FA values in the SCWM, which was prevented by intravenous MSC administration; means ± 95% CI and levels of significance are depicted, which were calculated with ANOVA (sham-SAL n=8, sham-MSC n=4, HI-SAL n=8, HI-MSC n=8). …”

Germination and biochemical changes in West Indian gherkin seeds under water stress at different temperatures by João Paulo Nobre de Almeida (4659739)

“…The experimental design was completely randomized, in 5 x 5 factorial scheme, composed of five osmotic potentials (0.0; -0.1; -0.2; -0.3 and -0.4 MPa) and four temperatures (20; 25; 30 °C and alternating temperatures of 20-30 ºC), with each treatment composed of four replicates of 50 seeds. …”