BIG1 is required for the survival of deep layer neurons, neuronal polarity, and the formation of axonal tracts between the thalamus and neocortex in developing brain by Jia-Jie Teoh (3929852)

“…<i>In vitro</i>, BIG1-deficient neurons showed a delay in neuronal polarization. BIG1-deficient neurons were also hypersensitive to low dose glutamate (5 μM), and died via apoptosis. …”

Table_1_Mesenchymal Stromal Cell-Derived Extracellular Vesicles Attenuate Dendritic Cell Maturation and Function.xlsx by Monica Reis (5947445)

“…MiR-21-5p mimic transfected DCs showed a clear trend of reduced CCR7 expression and a significantly decreased migratory ability toward the CCL21. …”

Data_Sheet_1_Mesenchymal Stromal Cell-Derived Extracellular Vesicles Attenuate Dendritic Cell Maturation and Function.docx by Monica Reis (5947445)

“…MiR-21-5p mimic transfected DCs showed a clear trend of reduced CCR7 expression and a significantly decreased migratory ability toward the CCL21. …”

Supplementary Material for: The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis by Santana P.T. (3632560)

Infected cells in the neighbourhood of CD8+ T cells secreting non-lytic factors. by Nafisa-Katrin Seich al Basatena (201133)

“…We tracked the proportion of wild type- and variant-infected cells in the immediate neighbourhood (radius = 1, i.e. 26 neighbours) of 5,425 secreting CD8+ T cells. …”

IPF fibroblasts are desensitized to collagen rich matrix induced cell death in the presence of 3MA or CQ. by Richard Seonghun Nho (54078)

“…All assays were performed in three separate experiments to measure fibroblast viability or their proliferation using IPF cells in lane 5 and control fibroblasts in lane 3 in an upper panel in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094616#pone-0094616-g001" target="_blank">Fig 1A</a>.…”

Do psychosocial factors modify the negative association between disability and life satisfaction in old age? by Thomas Puvill (726017)

“…The impact of (I)ADL disabilities on life satisfaction was strongest at age 50 and gradually decreased with increasing age (p trend < 0.001). Mental health explained more variance; 5.75% for depressive symptoms and 2.50% for loneliness and for social resources this ranged from 0.09% to 0.47% (all p < 0.001). …”

Fatigue indices and perceived exertion highlight ergometer specificity for repeated sprint ability testing by Hugo Kerhervé (618369)

“…During recovery, RPE was consistently higher on NMT at 1, 3 and 5 min postexercise compared to CE. These findings indicate that RSA performed on NMT induces greater fatigue and physiological load than CE, which originated in the lower resistive torque typically used on NMT compared to CE, resulting in a frontloaded power output profile from the greater acceleration and cadence. …”

Low electro-synthesis potentials improve permselectivity of polymerized natural phenols in biosensor applications by Monti, Patrizia

“…Polymers were obtained by means of constant potential amperometry, instead of cyclic voltammetry, in order to achieve multiple polymerizations, hence decreasing the time of realization and variability. …”
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Inner ear pathology in MPS IIIB mice at 30 wks. by Coy D. Heldermon (78170)

“…Plot of the number of hair cell profiles versus neuronal density, as seen in radial view in the lower base for 5 MPS IIIB and 5 WT mice at 30 wks. Differences in hair cell numbers by genotype are highly significant (t-test, p<.001). …”

Mathematical Modeling Reveals Kinetics of Lymphocyte Recirculation in the Whole Organism by Vitaly V. Ganusov (142019)

“…The model also predicts a relatively short average residence time of TDLs in the spleen (2.5 hours) and a longer average residence time of TDLs in major lymph nodes and Peyer's patches (10 hours). …”

DataSheet1_Long-Term Variation in Wintertime Atmospheric Diffusion Conditions Over the Sichuan Basin.docx by Guoyin Wang (10939987)

“…Both V_E and ASI reveal a decrease tendency of atmospheric diffusion condition from the northwestern portion of the basin to the southeast. …”

Distinct CLP migratory groups persist under low serum conditions. by Joël Beyeler (652358)

“…<p>The graphs show the RWC in scratch wound assays at 24 h in 0.3% FCS/DMEM (*p<0.05, **p<0.01, ***p<0.001). (A) Despite a general decrease of the RWC, “fast” and “intermediate” CLP groups could still be distinguished under low-serum conditions. …”

ChIP-seq findings for <i>Nr2f1</i>, <i>Nr2f2</i>, <i>Meis1</i>, and <i>Meis2</i> identify RARE enhancers in gene families. by Marie Berenguer (8856509)

“…<p>(A-B) <i>Nr2f1</i> and <i>Nr2f2</i> have RA-regulated peaks (red bars) for both H3K27ac (decreased) and H3K27me3 (increased) when RA is lost in E8.5 trunk from <i>Aldh1a2</i>-/- (KO) compared with WT. …”

Data_Sheet_1_Little Impact of NaCl Reduction in Swiss-Type Cheese.docx by Valérie Gagnaire (783586)

“…Casein hydrolysis in vitro was similar or higher at pH 5.2, i.e., cheese pH, compared to pH 7.5, and slightly decreased at the highest salt concentrations (3.0 and 4.4%). …”

Hepatitis C Virus Translation Preferentially Depends on Active RNA Replication by Helene Minyi Liu (139939)

“…When the movement of HCV RNA from the site of RNA synthesis to the Golgi complex was blocked by nocodazole, an inhibitor of ER-Golgi transport, HCV protein translation was surprisingly enhanced, suggesting that the translation of viral proteins occurred near the site of RNA synthesis. We also found that the translation of HCV proteins was dependent on active RNA synthesis: inhibition of viral RNA synthesis by an NS5B inhibitor resulted in decreased HCV viral protein synthesis even when the total amount of intracellular HCV RNA remained unchanged. …”

Table 1_Trends in the disease burden of maternal sepsis and other maternal infections attributable to iron deficiency from 1990 to 2021 and its projection until 2050.docx by Chunfeng Zhu (327990)

“…The ASMR and age-standardized DALY rate of MSMIs attributable to iron deficiency were negatively correlated with SDI. Projections indicated a continued decrease in the burden of MSMIs attributable to iron deficiency by 2050.…”

Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies by Gleb Kichaev (652009)

“…We validate our findings using a large scale meta-analysis of four blood lipids traits and find that the relative probability for causality is increased for variants in exons and transcription start sites and decreased in repressed genomic regions at the risk loci of these traits. …”

Expression of <i>LINC03045</i> in patient glioma samples from The Cancer Genome Atlas (TCGA) and The Genotype-Tissue Expression (GTEx) project. by Kathleen Tsung (18794564)

“…Cohorts divided into quartiles show a significant decrease in survival with increased expression levels in LGG (p = 0.002), but not GBM (p = 0.40). …”

Axon misguidance phenotypes in vivo occur where the Shh gradient is shallow. by Tyler F. W. Sloan (715369)

“…<p><b>(A)</b> Mouse e9.5 (left) and e10.5 (middle and right) spinal cord cross-sections immunostained for Shh. …”