Rapid Anti-Inflammatory Effects of Gonadotropin-Releasing Hormone Antagonism in Rheumatoid Arthritis Patients with High Gonadotropin Levels in the AGRA Trial by Anita Kåss (812567)

“…Potential anti-inflammatory effects of GnRH-antagonists may be most pronounced in patients with high GnRH and gonadotropin levels. Therefore, we investigated the efficacy and safety of a GnRH-antagonist, cetrorelix, in RA patients with high gonadotropin levels.…”

Global proteomic changes upon perturbation of Hsp90. by Teresa R. O’Meara (720286)

“…Non-denaturing IEX fractionation and MS experiments were performed on <i>lys2Δ/lys2Δ tetO-HSP90/hsp90Δ</i> cells that were untreated, treated with DOX to repress <i>HSP90</i> expression, or treated with 15 μM GdA to inhibit Hsp90 function. For DOX treatment, cells were treated with 0.05 μg/mL DOX overnight and then subcultured into medium with 5 μg/mL DOX for 4 hours before harvesting. …”

Evidence for rapid downward fecundity selection in an ectoparasite (Philornis downsi) with earlier host mortality in Darwin’s finches by Sonia Kleindorfer (95761)

“…Across a 12-year period, we observed a mean of ~17% P. downsi mortality in host nests with 55 ± 6.2 % host mortality, and a trend of ~66% higher host mortality throughout the study period. …”

DataSheet_1_Alteration of Gut Microbiome and Correlated Lipid Metabolism in Post-Stroke Depression.pdf by Wenxia Jiang (3567782)

“…The microbial composition of PSD showed a decreased species richness indices, characterized by 22 depleted OTUs mainly belonging to phylum Firmicutes, genus Blautia and Streptococcus. …”

Pituitary genomic expression profiles of steers are altered by grazing of high vs. low endophyte-infected tall fescue forages by Qing Li (84975)

“…To identify candidate regulatory mechanisms, we compared the global and selected targeted mRNA expression patterns of pituitaries collected from beef steers that had been randomly assigned to undergo summer-long grazing (89 to 105 d) of a high-toxic endophyte-infected tall fescue pasture (HE; 0.746 μg/g ergot alkaloids; 5.7 ha; <i>n</i> = 10; BW = 267 ± 14.5 kg) or a low-toxic endophyte tall fescue–mixed pasture (LE; 0.023 μg/g ergot alkaloids; 5.7 ha; <i>n</i> = 9; BW = 266 ± 10.9 kg). …”

Eigenvalue stability in the LHIGP module. by Amanda L. Caskenette (3692260)

“…<p>Patterns of stability for Cases 1–4 (a-d) starting from a food chain module and moving towards an exploitative competition module as <i>m</i> & <i>s</i> decrease from 1 to 0 (Parameter values: r = 1.5, K = 1, a_CR = 3, a_PC = 1, a_PR = 0.2, b_CR = 1.5, b_PC = 1, b_<i>PR</i> <i>= 1</i>, d_C = 0.3 (b and d), 0.5 (a and c), d_P = 0.1 (c and d), 0.15(a and b)).…”

Cooperatively coupled cargo translocation. by Aidan I. Brown (509994)

“…<p>(A) Cytosolic PEX5-cargo concentration vs. PEX5 cargo addition rate, . …”

Subcellular distribution of phosphorylated AQP2 in MDCK cells grown in 3D culture and in Brattleboro rat kidney. by William L. Rice (183510)

“…On the other hand, stimulation resulted in a significant (asterisk) decrease in pS261 (p = .002) and a significant increase in pS269 (p = .04). …”

Data_Sheet_1_An evaluation of nutrition, culinary, and production interventions using African indigenous vegetables on nutrition security among smallholder farmers in Western Kenya... by Emily V. Merchant (12267842)

“…Despite this, post-intervention, households that received NCI/PI had a higher WDDS relative to the control: WDDS 5.1 ± 1.8 vs. 4.2 ± 1.5, p = 0.035. …”

Impact of Age on the Cerebrovascular Proteomes of Wild-Type and Tg-SwDI Mice by James L. Searcy (225690)

“…Over 650 proteins were quantified in vessel-enriched fractions from the brains of 3 and 9 month-old wild-type (WT) and Tg-SwDI mice. Sixty-five proteins were significantly increased in older WT animals and included several basement membrane proteins (nidogen-1, basement membrane-specific heparan sulfate proteoglycan core protein, laminin subunit gamma-1 precursor and collagen alpha-2(IV) chain preproprotein). …”

Leukocyte infiltration signatures of human psoriasis and mouse psoriasiform lesions. by William R. Swindell (175427)

“…For each set of <i>n</i> signature transcripts associated with a given cell population, and for each psoriasiform phenotype, we identified the number of transcripts with increased expression in mouse psoriasiform lesions (<i>n</i>₁) and the number of transcripts with decreased expression in mouse psoriasiform lesions (<i>n</i>₂). …”

Supramolecular Structures and Assembly and Luminescent Properties of Quinacridone Derivatives by Kaiqi Ye (1436131)

“…In contrast, high efficiencies (21.5−12.0 cd/A) are achieved for a wider dopant concentration range of 0.5−5.0% when Alq₃:<b>2</b> films are employed as emitting layer. …”

Presentation_1_CD56-negative NK cells: Frequency in peripheral blood, expansion during HIV-1 infection, functional capacity, and KIR expression.pptx by Alexander T. H. Cocker (8436300)

“…We found in 757 individuals, from a combined 28 studies and 6 datasets, that the CD56neg subset constitutes 5.67% of NK cells in healthy peripheral blood, while HIV-1 infection increases this population by a mean difference of 10.69%. …”

DataSheet_1_CD56-negative NK cells: Frequency in peripheral blood, expansion during HIV-1 infection, functional capacity, and KIR expression.pdf by Alexander T. H. Cocker (8436300)

“…We found in 757 individuals, from a combined 28 studies and 6 datasets, that the CD56neg subset constitutes 5.67% of NK cells in healthy peripheral blood, while HIV-1 infection increases this population by a mean difference of 10.69%. …”

Airborne health-related substances and their association with the SRB. by Yanan Long (11784717)

“…Each plot shows bar plots of regression coefficients and 95% confidence intervals (error bar) of the second to the seventh septiles, with the first septile chosen as the reference level. We rank the 12 models by the statistically significant factor’s association strength with at least one statistically significant coefficient by decreasing ΔIC; septiles whose coefficients are not significantly different from 0 at the 95% confidence level have been plotted with a reduced alpha level. …”

Data_Sheet_1_Seed Dormancy and Soil Seed Bank of the Two Alpine Primula Species in the Hengduan Mountains of Southwest China.DOCX by De-Li Peng (3204021)

“…Germination was first tested using fresh seeds at two alternating temperatures (15/5 and 25/15°C) and five constant temperatures (5, 10, 15, 20, and 25°C) in light and dark, and again after dry after-ripening at room temperature for 6 months. …”

Supplementary materials. by Yongki Welliam (21030005)

“…Meta-analysis revealed that increasing OPN (SMD = 5.52, 95% CI = 1.59–9.44, p = 0.01) and KIM-1 (SMD = 1.45, 95% CI = 0.50–2.39, p = 0.0027), as well as decreasing Fetuin-A level (SMD = -1.31, 95% CI = -2.37 – -0.26, p = 0.01) were significant in CKD patients with ESRD. …”

Effect of lesimarin against thioacetamide-induced liver cirrhosis in rat by Sang-Ho Ra (8185944)

“…Lesimarin, lecithin, silymarin and AMB were administered at a dose of 1.0, 1.0, 0.5, 1.0g/kg body weight orally daily for three months, respectively. …”

KaiC Monomer Exchange Revealed by Changes in FRET Signal by Tetsuya Mori (208605)

“…The decrease in fluorescence intensity at 470 nm was plotted as a function of time. …”

Microarray-based analysis of gene expression profiles in peripheral blood of patients with acute primary angle closure by Jin Wook Jeoung (669425)

“…<p><i>Background</i>: We investigated the expression of molecules in peripheral blood mononuclear cells (PBMCs) and plasma of patients with acute primary angle closure (APAC).…”