Image 3_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Lastly, we co-cultured ATG7^Δβ-cell islet cells with diabetogenic BDC2.5 helper T cells and evaluated T cell activation.…”

Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif by Matthew C. Austin (20633168)

“…Lastly, we co-cultured ATG7^Δβ-cell islet cells with diabetogenic BDC2.5 helper T cells and evaluated T cell activation.…”

Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Lastly, we co-cultured ATG7^Δβ-cell islet cells with diabetogenic BDC2.5 helper T cells and evaluated T cell activation.…”

Recovery of Bradyrhizobium cells and effects on the physiological quality of soybean seeds sown in dry soil by Débora Bueno Bernardo Pinto (14516629)

“…In the first experiment, irrigation was applied with 2 h, 1, 4, 11, 18, or 21 days after sowing; in the second experiment, sowing was carried out 2 h, 1, 5, 12, 14, or 20 days before irrigation. Each time represented a treatment in a completely randomized design. …”

Model for grapevine bud cold hardiness and budbreak response: Data files by Amaya Atucha (20927132)

“…Recent studies demonstrate freezing temperatures promote chill accumulation and cold hardiness influences time to budbreak—the phenotype used for dormancy evaluations. Here we evaluated bud cold hardiness and budbreak responses of grapevines (<i>Vitis </i>hybrids) throughout chill accumulation under three treatments: constant (5 °C), fluctuating (−3.5 to 6.5 °C daily), and field conditions (Madison, Wisconsin, USA). …”

Oral lactate intensifies insulin toxicity during severe insulin-induced hypoglycemia in mice by Vanessa Rodrigues Vilela (12848422)

“…<div><p>ABSTRACT We investigated whether oral lactate could prevent seizures and deaths in mice with severe hypoglycemia induced by a high dose of insulin. …”

DataSheet_1_Preterm Birth Is Associated With Immune Dysregulation Which Persists in Infants Exposed to Histologic Chorioamnionitis.docx by Gemma Sullivan (11340801)

“…Pro-inflammatory proteins IL-6, MCP-1 and CRP were elevated in the cord blood of preterm infants whilst BDNF, C3, C9, IL-18, MMP-9 and RANTES were decreased, compared to infants born at term. In preterm infants, exposure to HCA was associated with elevations in 8 immune proteins on postnatal day 5 (BDNF, C3, C5a, C9, IL-8, MCP-1, MIP-1β and MMP-9) when compared to preterm infants who were not exposed.…”

Table_1_Sex differences in hippocampal β-amyloid accumulation in the triple-transgenic mouse model of Alzheimer’s disease and the potential role of local estrogens.DOCX by Yu-Ting Hu (4745274)

“…In SH-SY5Y cells infected with lentivirus containing the amyloid precursor protein construct C99, we observed significantly increased extracellular Aβ and decreased expression of intracellular EGR1 and AChE. …”

Immunohistochemical analysis. by Dalal G. Al-Adwani (8190696)

“…<p><b>A:</b> Representative photomicrographs (40x objective) of lumbar spinal cord ventral grey horn from rats of all groups immunostained for NeuN (NeuN–Anti-NeuN, Clone A60, Mouse Monoclonal Antibody) at week 3 (A1, A3, A5, A7 and A9) and week 6 (A2, A4, A6, A8 and A10) following nerve crush injury. …”

Tumor Heterogeneity by Sabrina L Spencer (20366)

“…As the tumor begins to form, there is typically a slow increase in the degree of tissue heterogeneity followed by a sudden increase, an equally sudden decrease, and then often another increase as the tissue reaches 9 × 10⁵ cells.…”

Influence of pre-treatment blood pressure levels on antihypertensive drug benefits in diabetics: the roadmap experience by Christos Chatzikyrkou (2792542)

“…</p> <p><b>Results</b>: BP at randomisation was 136.2(15.3)/80.6(9.5) [mean (SD)] mmHg with a range of 87–213/37–123 mmHg. …”

Cytoprotective gene regulation is essential to lifespan extension by diverse mechanisms. by David E. Shore (123998)

“…Only 5 of the 29 gene inactivations result in a 15% or greater reduction in wild-type (N2) lifespan, and most (20 of 29) reduce wild-type lifespan by less than 10% (column 5). …”

Spontaneous firing rates of ON-type ganglion cells were increased in diabetic mice. by Jun Yu (5904)

“…In diabetic mice, a considerable decrease was observed in the percentage of cells with an average firing frequency <5 Hz, but in the other two frequency bands (≥5 Hz) the percentage of diabetic cells were larger than the control group.…”

DataSheet1_Increasing but Variable Trend of Surface Ozone in the Yangtze River Delta Region of China.pdf by Keqin Tang (11208198)

“…The leading O₃ formation regime in 2014–2017 is diagnosed as VOC-limited (21%) or mix-limited (58%), with the help of a simulated indicator HCHO/NO_y. Under such condition, the decreasing NO₂ (2.8% yr⁻¹) and increasing VOCs (3.6% yr⁻¹) in 2014–2017 led to a rapid increment of O₃. …”

TUNEL staining and cell proliferation in the OB by Haydn M Prosser (40070)

“…Note, the difference in size of the OB at 5 × magnification. Scale bars: 100 µm (A and B); 20 µm (C); 500 µm (E and F).…”

Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy? by Stephanie W. Vrede (17751147)

“…We studied 894 patients with endometrial cancer over about 4.5 years, in which 11.5% had anaemia, 8.8% thrombocytosis and 12.7% leucocytosis. …”

Cytoskeleton and major extracellular matrix proteins were analyzed by immunofluorescence. by Ludwig Stanislas Loison-Robert (4797525)

“…The observed decrease in type 1 collagen, when DPSC were in contact with biomaterials, was confirmed using RT-qPCR (5J), whereas protein secretion was not modified by the experimental conditions (Fig 5K). …”

Estimation of PWM cutoff score from fraction of occupied STAT1 binding sites. by Christoph D. Schmid (72046)

“…<p>5 454 192 potential STAT1 binding sites in the human genome are grouped according their PWM score. …”

Temperature Dependence of the Contributions of Positive and Negative Design to the Gap in Simulations of Lattice Model Sequences Designed To Be Stable at Various Temperatures by Igor N Berezovsky (59807)

“…Positive design results in significant lowering of the native state energy (energy decrease in the interval of temperatures <i>T_env</i> = 0.2/0.8 has a slope equal to −5.22, black line). …”

Effect of Hsa-miR-185* exogenous expression on TrkB-T1 levels in HEK293 cell line. by Gilles Maussion (156014)

“…<p>A: Decrease of <i>TrkB-T1</i> in cells transfected with mimic compared to the negative control. …”