The impact of supervised weight loss and intentional weight regain on sex hormone binding globulin and testosterone in premenopausal women by Mira Aubuchon (2747557)

“…<p>What is the impact of intentional weight loss and regain on serum androgens in women? We conducted an ancillary analysis of prospectively collected samples from a randomized controlled trial. …”

Model fits to data from the <i>in vitro</i> killing assay. by Thea Hogan (631181)

“…<p>We applied the model of CTL-target conjugation and killing to data from the <i>in vitro</i> killing assay, using T and B cell targets pulsed at four different doses of peptide (decreasing, top to bottom). …”

Sucrose consumption test. by Rafael Delgado y Palacios (498616)

“…<p>The rats were presented with a sucrose solution (1.5%) for one hour after 14 hours of food and water deprivation in order to evaluate their hedonic state during the CMS procedure (8 weeks). …”

Changes in the perinuclear actin stress fibers and nuclear geometry for different rigidities. by Renu Vishavkarma (633732)

“…<p>(a–d) The observed decrease in stress fiber density as function of substrate rigidity for substrates with elastic modulus 65 kPa, 23 kPa, 5 kPa and 3 kPa respectively (also see panel in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0107895#pone.0107895.s011" target="_blank">Fig. …”

Monitoring ciliary entry and exit of Smo-mEos2 in SAG-treated cells. by Jynho Kim (614435)

“…<p>(A) Schematic diagram of drug treatment and photoconversion of NIH 3T3/Smo-mEos2 cells. …”

Supplemental Figures 1-7 from Erlotinib Pretreatment Improves Photodynamic Therapy of Non–Small Cell Lung Carcinoma Xenografts via Multiple Mechanisms by Shannon M. Gallagher-Colombo (14918058)

“…Supplemental Figure 4. VEGF levels decrease in A549 tumors with pre-PDT administration of erlotinib Supplemental Figure 5. …”

Lack of cluster formation upon unilateral PLL addition. by Yuri N. Antonenko (241873)

“…<p>Unilateral PLL addition at a concentration of 2.5 µM per lysine monomer, only has a minor effect on the lifetime <i>τ_P</i> of OPg dimers even at 1 M KCl on the opposite side. …”

Signalling via the Ras-RAF arm of ERK-MAPK is required for HCMV reactivation. by Verity G. Kew (577428)

“…IE RNA expression was expressed as a fold decrease compared to mock treated control <b>C</b>) immature DCs (1) were incubated with DMSO (2,3) or ERK (4,5), tpl2 (6,7) and Raf (8,9) inhibitors for 1 hour then stimulated with LPS (black) or IL-6 (grey) to promote reactivation. …”

Relative EEG power density per genotype. by Carolin F. Reichert (667435)

“…During the early morning hours (i.e., during the nap scheduled to 5:20–6:00 a.m.), highlighted by black boxes, G/A-allele carriers showed a relative decrease specifically in the range of 8–16 Hz (A), which was not present in G/G-allele carriers (B).…”

Microarray analyses of the transcriptome of diploid (D) and tetraploid (T) HCT116 cells treated with cisplatin, Chk1 inhibitor or the combination of both. by Ilio Vitale (82793)

“…Each row represents the combination of two dye-swap experiments compared to untreated control cells and each column represents a single gene. Red and green colors indicate an increase and a decrease, respectively, in the expression of genes as compared to unstimulated control cells. …”

Microscopic Study of Hydroxyapatite Dissolution As Affected by Fluoride Ions by Ki-Young Kwon (2190616)

“…In the presence of 10 mM NaF, individual surface step retraction velocities decreased by about a factor of 5 as compared to NaF-free conditions. …”

Low-dose curcumin treatment increases OEC proliferation. by Johana Tello Velasquez (652843)

“…<p>(A–D). Increased proliferation of OECs was observed after treatment with 0.5 µM curcumin (B) or 0.5 µM curcumin combined with G5 supplement (D); cells appeared to have longer processes and formed a net-like structure. …”

Marked Reduction of AKT1 Expression and Deregulation of AKT1-Associated Pathways in Peripheral Blood Mononuclear Cells of Schizophrenia Patients by Nico J. M. van Beveren (51667)

“…<div><h3>Background</h3><p>Recent studies have suggested that deregulated AKT1 signaling is associated with schizophrenia. We hypothesized that if this is indeed the case, we should observe both decreased AKT1 expression as well as deregulation of AKT1 regulated pathways in Peripheral Blood Mononuclear Cells (PBMCs) of schizophrenia patients.…”

Data_Sheet_3_High Rates of Genome Rearrangements and Pathogenicity of Shigella spp..CSV by Zaira Seferbekova (10583336)

“…We found that Shigella experienced exceptionally high rates of intragenomic rearrangements and had a decreased rate of homologous recombination compared to pathogenic and non-pathogenic E. coli. …”

Image_1_High Rates of Genome Rearrangements and Pathogenicity of Shigella spp..pdf by Zaira Seferbekova (10583336)

“…We found that Shigella experienced exceptionally high rates of intragenomic rearrangements and had a decreased rate of homologous recombination compared to pathogenic and non-pathogenic E. coli. …”

Table2_Targeted RNAi screen identifies transcriptional mechanisms that prevent premature degeneration of adult photoreceptors.xlsx by Spencer E. Escobedo (15415727)

“…From an initial set of 155 RNAi lines each targeting a unique gene and spanning a diverse set of transcription factors, chromatin remodelers, and histone modifiers, we identified 18 high-confidence target genes whose decreased expression in adult photoreceptors leads to premature and progressive retinal degeneration. …”

Image_2_High Rates of Genome Rearrangements and Pathogenicity of Shigella spp..pdf by Zaira Seferbekova (10583336)

“…We found that Shigella experienced exceptionally high rates of intragenomic rearrangements and had a decreased rate of homologous recombination compared to pathogenic and non-pathogenic E. coli. …”

Data_Sheet_4_High Rates of Genome Rearrangements and Pathogenicity of Shigella spp..CSV by Zaira Seferbekova (10583336)

“…We found that Shigella experienced exceptionally high rates of intragenomic rearrangements and had a decreased rate of homologous recombination compared to pathogenic and non-pathogenic E. coli. …”

Table1_Targeted RNAi screen identifies transcriptional mechanisms that prevent premature degeneration of adult photoreceptors.xlsx by Spencer E. Escobedo (15415727)

“…From an initial set of 155 RNAi lines each targeting a unique gene and spanning a diverse set of transcription factors, chromatin remodelers, and histone modifiers, we identified 18 high-confidence target genes whose decreased expression in adult photoreceptors leads to premature and progressive retinal degeneration. …”

Data from: Extinction of rare fish predicts an abrupt loss of ecological function in the future of Amazonian streams by Lucas Colares (11379678)

“…</p> <p>5. We propose an extinction risk assessment based on the ecosystem, and recommend that future studies apply our approach to other taxa and ecosystems, to better understand the effects of human impacts on ecosystem functioning.…”