Dysregulation of the Transforming Growth Factor β Pathway in Induced Pluripotent Stem Cells Generated from Patients with Diamond Blackfan Anemia by Jingping Ge (636557)

“…We also observed the up-regulation of <i>TGFβ1R</i>, <i>TGFβ2</i>, <i>CDKN1A</i> and <i>SERPINE1</i> mRNA, and the significant decrease of <i>GATA1</i> mRNA in the primitive multilineage progenitors. …”

Blue-light perception defect at decreasing levels of <i>AtPP7</i> expression is compensated under a triggering threshold. by Thierry Genoud (50956)

Heterologous Immunity Triggered by a Single, Latent Virus in <i>Mus musculus</i>: Combined Costimulation- and Adhesion- Blockade Decrease Rejection by Jonathan M. Beus (441623)

“…<div><p>The mechanisms underlying latent-virus-mediated heterologous immunity, and subsequent transplant rejection, especially in the setting of T cell costimulation blockade, remain undetermined. To address this, we have utilized MHV68 to develop a rodent model of latent virus-induced heterologous alloimmunity. …”

Table_5_miR-181a-5p Regulates TNF-α and miR-21a-5p Influences Gualynate-Binding Protein 5 and IL-10 Expression in Macrophages Affecting Host Control of Brucella abortus Infection.P... by Patrícia P. Corsetti (459690)

“…We observed that treating macrophages with a mmu-miR-21a-5p mimic enhanced bacterial growth, whereas transfection of its inhibitor reduced Brucella load in macrophages. …”

Repeated LSPC treatment prolongs survival of and decreases PrP^Res accumulation in a subset of prion-infected mice. by Heather Bender (363996)

DataSheet_1_UFR2709, a Nicotinic Acetylcholine Receptor Antagonist, Decreases Ethanol Intake in Alcohol-Preferring Rats.docx by Gabriel Quiroz (8068676)

Supplementary Material for: Optimistic Youth: Young Adults Predicted a Faster Decrease in Risk during COVID-19 Emergency State in Portugal by Scaletti S. (12434691)

A PPARα Promoter Variant Impairs ERR-Dependent Transactivation and Decreases Mortality after Acute Coronary Ischemia in Patients with Diabetes by Sharon Cresci (53599)

“…Consistent with previous descriptions of PPARα in experimental models and human disease, we describe a novel <em>PPARA</em> promoter SNP that decreases transcriptional activation of <em>PPARA</em> and protects against mortality in diabetic patients after ACS.…”

S1 Data - by Richard Junior Zapata Dongo (17912565)

“…In addition, our analysis using bioinformatics indicated that ABT-199 not only targets BCL2 but also binds to the active site of all ALK mutants, it was contrasted by <i>in vitro</i> ALK kinase activity inhibition by ABT-199 (5.5 μM). This interaction was further supported by a significant decrease of ALK phosphorylation in single and combination treatment with 300nM ABT-199. …”

Change of SMAD4 after TGFβ inhibitor /activator treatment. by Jingping Ge (636557)

“…Protein levels were measured by Western blot analysis. A) Decrease of total p-SMAD2 after SB431542 treatment in all iPSCs, and increase of p-SMAD2 in both DBA iPSCs after the TGFβ1 treatment. …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”

Rab7A decreases BST2 cell surface expression and is required for Vpu-induced BST2 cell surface downregulation. by Marina Caillet (198168)

“…HeLa cells transfected with either control siRNA (siLuc) or siRNA targeting Rab7A were infected with VSV-G pseudotyped NL4-3 HIV-1 (WT or Udel) at a MOI of 0.5. …”

PhoU is not substituted by artificial upregulation of σ^S<i>via arcB</i> or <i>rssB</i> deletions, but is suppressed by deletion of <i>arcA</i>. by Janet L. Gibson (736950)

<i>V. cholerae</i> exposure substantially remodels gene expression. by Longjun Pu (20685717)

The impact of the COVID-19 pandemic on the decrease in the use of intensive care units in the postoperative period of anatomic lung resections. A retrospective analysis by ISMAEL RODRIGO DIAS (12990222)

Kcnk5b activity induces IP₃R-mediated Ca²⁺ release from the ER. by Xiaowen Jiang (8291814)

Emission spectra of S100A1 fluorescence titrations exhibiting decreasing fluorescence intensities with increasing concentration of S100B at the μM level. by Md. Imran Khan (4853302)

The major role of <i>sarA</i> in limiting <i>Staphylococcus aureus</i> extracellular protease production <i>in vitro</i> is correlated with decreased virulence in diverse clinical... by Mara J. Campbell (14579826)

Molecular docking showed that ABT-199 can fit into active site of ALK^Mutant. by Richard Junior Zapata Dongo (17912565)