C-terminal BNIP3 phosphorylation decreases the BNIP3-OPA1 interaction at the mitochondrial membrane. by Katherine E. Liu (759143)

Hyperlipidemia-Associated Renal Damage Decreases Klotho Expression in Kidneys from ApoE Knockout Mice by Cristina Sastre (503532)

“…Hyperlipidemia accelerates the progression of renal damage, but the mechanisms of the deleterious effects of hyperlipidemia remain unclear.</p><p>Methods</p><p>We evaluated whether hyperlipidemia modulates Klotho expression in kidneys from C57BL/6 and hyperlipidemic apolipoprotein E knockout (ApoE KO) mice fed with a normal chow diet (ND) or a Western-type high cholesterol-fat diet (HC) for 5 to 10 weeks, respectively.…”

Gramine Derivatives Targeting Ca²⁺ Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases by Rocío Lajarín-Cuesta (1530580)

“…Hence, we propose this multitarget approach as a new and promising strategy for the treatment of neurodegenerative diseases.…”

FEF inactivation decreased ipsilesional and contralesional microsaccade peak velocities, both before and after cue onset. by Tyler R. Peel (2935848)

“…<p>(<b>A</b>) Unilateral (left) FEF inactivation reduced peak velocity for contralesional microsaccades independently of amplitude in our example monkey DZ and also decreased peak velocities for ipsilesional microsaccades. …”

IL-10^−/− mice develop a less severe PCM associated with increased cellular immunity that results in decreased mortality rates. by Tânia A. Costa (440296)

Decreased tumor cell invasion induced by MMP-2 and MT1-MMP null fibroblasts in vitro by Wenyue Zhang (16665)

PA J10 mutant does not affect the formation of VLPs but decreases viral RNA packaging efficiency. by Yuhong Liang (335908)

Neuronal cell cultures derived from embryos injected with APPb-MO had decreased neurite length. by Ping Song (169215)

“…The neurons from the embryos injected with 8 ng of APPb-MO showed a decrease in neurite length compared to neurons from the control embryos (un-injected). …”

S3 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

S2 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

S1 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

S4 Data - by Dwight D. Harris (14484648)

“…Trichrome stain demonstrated a significant decrease in perivascular and interstitial fibrosis in the SIT group relative to CON (all p<0.05). …”

Decreased E/I synapse ratio and loss of cortico-LA synaptic plasticity in the absence of coronin 1. by Rajesh Jayachandran (542641)

“…(E) Coronin 1–deficient animals (Cor1 −/−, red symbols) exhibited normal thalamo-LA LTP [<i>p</i><0.05 versus baseline; <i>p</i>>0.05 versus wild-type (WT, gray symbols), Student's <i>t</i> test]. Scale bars, 2 mV and 10 ms. …”

Filamentation induced by DTPA is associated with a decrease in Nrg1 protein level, and requires the cAMP-PKA pathway and the kinase Sok1. by Elizabeth J. Polvi (3163500)

DataSheet1_Calmodulin mutations affecting Gly114 impair binding to the NaV1.5 IQ-domain.docx by Malene Brohus (840080)

“…We therefore hypothesized that the G114R variant specifically would interfere with Na_V1.5 binding. …”

Neutralization of JRFL WT and mutant viruses by different MAbs and CD4-IgG2. by Chitra Upadhyay (817121)

“…B) JRFL WT and mutant neutralization by MAbs targeting V2i, V3, V2q, and the CD4bs and by CD-IgG2. …”

Table_1_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.docx by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

Image_3_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.tif by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

Image_1_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.tif by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”

Image_2_Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves’ Disease.tif by Ziyi Chen (458298)

“…Specifically, the expression of pro-inflammatory and chemotactic genes (IL1B, IL13, IL8, and CCL4) was increased in pGD, whereas Th17 and Treg cells associated genes (RORC, CARD9, STAT5A, and SATB1) decreased in pGD. Additionally, TCR diversity was negatively correlated with the expression of pro-inflammatory or chemotactic genes (FASLG, IL18R1, CCL24, and CCL14). …”