Image3_Abnormal transcriptome-wide DNA demethylation induced by folate deficiency causes neural tube defects.jpg by Shan Wang (120085)

“…In this study, our data demonstrated genome-wide enrichment of 5-hydroxymethylcytosine (5hmC) modification on active transcriptional start sites (TSS) and decreased 5-methylcytosine (5mC) binding to TSS under folate deficiency in mESCs (mouse embryonic stem cells). …”

Image_1_Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion.tif by Alejandro Domínguez-Rodríguez (279819)

“…Moreover, Ucn-2 recovered the amplitude of [Ca²⁺]_i transient and modulated the expression of several proteins related to [Ca²⁺]_i homeostasis, such as TRPC5 and Orai1 channels. Using Neonatal Rat Ventricular Myocytes (NRVM) we demonstrated that Ucn-2 blunted I/R-induced Store Operated Ca²⁺ Entry (SOCE), decreased the expression of TRPC5 and Orai1 as well as their interaction in reperfusion.…”

Image_2_Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion.tif by Alejandro Domínguez-Rodríguez (279819)

“…Moreover, Ucn-2 recovered the amplitude of [Ca²⁺]_i transient and modulated the expression of several proteins related to [Ca²⁺]_i homeostasis, such as TRPC5 and Orai1 channels. Using Neonatal Rat Ventricular Myocytes (NRVM) we demonstrated that Ucn-2 blunted I/R-induced Store Operated Ca²⁺ Entry (SOCE), decreased the expression of TRPC5 and Orai1 as well as their interaction in reperfusion.…”

Pituitary genomic expression profiles of steers are altered by grazing of high vs. low endophyte-infected tall fescue forages by Qing Li (84975)

“…To identify candidate regulatory mechanisms, we compared the global and selected targeted mRNA expression patterns of pituitaries collected from beef steers that had been randomly assigned to undergo summer-long grazing (89 to 105 d) of a high-toxic endophyte-infected tall fescue pasture (HE; 0.746 μg/g ergot alkaloids; 5.7 ha; <i>n</i> = 10; BW = 267 ± 14.5 kg) or a low-toxic endophyte tall fescue–mixed pasture (LE; 0.023 μg/g ergot alkaloids; 5.7 ha; <i>n</i> = 9; BW = 266 ± 10.9 kg). …”

Data_Sheet_1_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.docx by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_4_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xls by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_1_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xlsx by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_2_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xls by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_3_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xls by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_3_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xls by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_4_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xls by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_4_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xls by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Data_Sheet_1_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.docx by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Data_Sheet_1_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.docx by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_1_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xlsx by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_3_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xls by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_2_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xls by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_2_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xls by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

Table_1_Dietary Amylose/Amylopectin Ratio Modulates Cecal Microbiota and Metabolites in Weaned Goats.xlsx by Kefyalew Gebeyew (11744633)

“…The metabolomics results revealed that feeding a diet containing 50% high amylose decreased the concentration of fatty acyls-related metabolites, including dodecanedioic acid, heptadecanoic acid, and stearidonic acid ethyl ester compared with the T1 diet. …”

The outcomes of different dosing strategies on the aggregate number of resistant bacteria (left panel) and time with symptoms (bacterial loads >10⁷, right panel) are con... by Patricia Geli (188461)

“…Parameters used to achieve regulated commensal dynamics are <i>E_max</i> = 1, <i>a</i> = 0.2, <i>K</i> = 10¹⁵, λ = 1.8, <i>c_50R</i> = 13.1, <i>c_50S</i> = 1.3, γ = 50, <i>b</i> = 10⁶, δ = 50, μ = 10⁻⁸, ξ_R = 0.2, and ξ_S = 0.1. …”