Image_1_18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways.TIF by Xiao Chen (2756308)

“…For underlying molecular mechanisms, 18β-GA inhibited RANKL-induced phosphorylation of p65, p50, and IκB, blocked p65 nuclear translocation and decreased the DNA-binding activity of NF-κB. …”

P2Y₁₂ deficiency in microglia improved neuron survival following OGD and prevented microglial clustering. by Corey M. Webster (442040)

DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Con... by Melanie Thompson (207727)

“…<div><p>GV-TH-01, a Phase 1 open-label trial of a DNA prime—Modified Vaccinia Ankara (MVA) boost vaccine (GOVX-B11), was undertaken in HIV infected participants on antiretroviral treatment (ART) to evaluate safety and vaccine-elicited T cell responses, and explore the ability of elicited CD8+ T cells to control viral rebound during analytical treatment interruption (TI). …”

Lumican modulates adipocyte function in obesity-associated type 2 diabetes by Clarissa Strieder-Barboza (4662910)

Male-biased effects of ubiquitous RNAi-mediated <i>bmm</i> inhibition reduces sex differences in triglyceride storage and breakdown. by Lianna W. Wat (8339454)

“…(K) Between 0 and 12 hours STV, triglyceride breakdown in <i>da>UAS-bmm-RNAi#2</i> (BDSC #25926) females was blocked, whereas triglyceride levels decreased in <i>da>+</i> and <i>+>UAS-bmm-RNAi#2</i> control females (<i>p</i> = 0.18, 0.036, and 9.9 × 10⁻⁵, respectively; one-way ANOVA followed by Tukey HSD test), whereas we observed similar magnitudes of triglyceride breakdown between 12 and 24 hours STV in <i>da>+</i>, <i>+>UAS-bmm-RNAi#2</i>, and <i>da>UAS-bmm-RNAi#2</i> (BDSC #25926) females (<i>p</i> = 0.032, 0.28, and 0.022, respectively; one-way ANOVA followed by Tukey HSD test). …”

Table 1_A murine model of gestational diabetes reveals MASLD risk and alterations in markers of hepatic mitochondrial metabolism.docx by Grace E. Shryack (21596426)

“…</p>Results<p>Progressing gestation in both CD and GDM dams significantly decreased protein and mRNA markers of hepatic mitochondrial biogenesis (Pgc1-α, Tfam), autophagy (Atg5, Sqstm1), mitophagy (Pink1, Bnip3) and lipid handling (Ampk, pAMPK/AMPK, FAS, ACC, pACC, Mttp) with a main effect for time (P<0.05). …”

Effects of rTMS in the DMN present in deactivation task-related networks. by Cleofé Peña-Gomez (113858)

Table2_Short-term organic fertilizer substitution increases sorghum yield by improving soil physicochemical characteristics and regulating microbial community structure.xlsx by Mengen Nie (20143902)

“…Compared with the CF treatment, a medium ratio (50%) of organic fertilizer substitution significantly reduced soil alkalization (by 3.05%), improved soil nutrients, enhanced soil enzyme activities, and increased sorghum yield (P < 0.05). …”

Table1_Short-term organic fertilizer substitution increases sorghum yield by improving soil physicochemical characteristics and regulating microbial community structure.docx by Mengen Nie (20143902)

“…Compared with the CF treatment, a medium ratio (50%) of organic fertilizer substitution significantly reduced soil alkalization (by 3.05%), improved soil nutrients, enhanced soil enzyme activities, and increased sorghum yield (P < 0.05). …”

Data Sheet 1_Fine root decomposition and nutrient release of different age Caragana intermedia plantation in alpine sandy land.xlsx by Qingxue Li (363724)

“…RDA analysis showed that the K content of fine root had the highest explanation for the mass loss and nutrient release (68.50-91.50%), followed by the C content (5.10-20.20%), and both reached a very significant level (P< 0.01).…”

GSK461364 plus docetaxel reduce tumorsphere formation of SUM149 and SUM159. by Antonio Giordano (55096)

“…<p>(A, histograms and B, pictures) For the primary tumorsphere assay, we analyzed the tumorsphere formation in presence or absence of docetaxel, GSK461364, and the combination at the IC₅₀ concentrations identified in the proliferation assay; SUM149 and SUM159 cells were plated at a density of 20,000 cells per well in ultra-low attachment 6 well plates and after 24 hours treated with DMSO (control), docetaxel IC₅₀, GSK461364 IC₅₀, or both in combination. …”

Preservation of the activated PaDHPAO activity. by Soraya Pornsuwan (419434)

“…<p>(A) Percentage of relative activity of the activated PaDHPAO decreased after the solution was kept on ice for 7–8 hours in 50 mM potassium phosphate buffer, pH 7.0. …”

Data_Sheet_1_Predicting the prevalence of type 2 diabetes in Brazil: a modeling study.PDF by Patrícia Vasconcelos Leitão Moreira (11378275)

“…If obesity declined by 5% per year in 16 years as an optimistic target (Scenario 2), the prevalence of diabetes decreased from 26.3 to 21.2, representing a 19.4% drop in diabetes prevalence.…”

Data_Sheet_1_Prevalence and incidence of stroke, white matter hyperintensities, and silent brain infarcts in patients with chronic heart failure: A systematic review, meta-analysis... by Sean Tan (13796668)

“…Meta-regression showed IS prevalence was positively correlated with decreasing anticoagulant usage.</p>Conclusion<p>We obtained estimates for the prevalence of IS, WMH, and SBI in HF from systematic review of the literature.…”

Age-Associated Lipidome Changes in Metaphase II Mouse Oocytes by Hyuck Jun Mok (600066)

“…To investigate if aged oocytes display an altered lipidome compared to young oocytes, we performed a global lipidomic analysis between oocytes from 4-week-old and 42 to 50-week-old mice. …”

Cut-off performance dependence of Sting-LDA-WNA classifier. by Fábio R. de Moraes (516010)

“…When the cut-off is increased from 0.10 to 0.50, the accuracy increases and reaches its peak, and then it gradually decreases with a further increase in the cut-off value. …”

Voxelwise comparison between MS patients and healthy subjects. by Mark Lyksborg (583318)

Comparison of the Predictive Values of CKD in Each Surrogate Maker of Obesity. by Keiichi Odagiri (522165)

Modifying FA metabolism alters pro-inflammatory cytokine expression in PHN. by Joseph W. McFadden (679148)

Fitting curve of CCS and rock bridge angle. by Gaojian Hu (11457537)