Image_1_Circulating methylation level of HTR2A is associated with inflammation and disease activity in rheumatoid arthritis.tif by Jianan Zhao (9516635)

“…The DNA methylation levels of about 218 bp from chr13: 46898190 to chr13: 46897973 (GRCh38/hg38) around HTR2A cg15692052 from patients were analyzed by targeted methylation sequencing.</p>Results<p>We measured methylation status for 7 CpGs in the promoter region of HTR2A and obseved overall methylation status are signficantly increased in RA compared with normal inviduals (FDR= 9.05 x 10^-5). …”

Biodegradable thermoplastic polyurethane composites as potential plating systems in pediatric facial fractures by ALANI, AYA AHMED

“…Due to the rapid growth of facial bone in the pediatric age group, the use of metallic plates would require a second surgical intervention to remove it. The alternative is biodegradable plating systems which are safe but not without complications, including learning curve, decreased stability, cost, and infection. …”
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Pterostilbene-Isothiocyanate Conjugate Suppresses Growth of Prostate Cancer Cells Irrespective of Androgen Receptor Status by Kumar Nikhil (547014)

“…The conjugate molecule caused 50% growth inhibition (IC₅₀) at 40±1.12 and 45±1.50 μM in AR positive (LNCaP) and negative (PC-3) cells, respectively. …”

Fabrication of poly(<b>γ</b>-glutamic acid)-based biopolymer as the targeted drug delivery system with enhanced cytotoxicity to APN/CD13 over-expressed cells by Li Zhang (8200)

“…PAMCN enhanced the efficacy of CDDP to HUVEC cells with the half maximal inhibitory concentration (IC₅₀) value decreased to 90.83 ± 33.00 μg/ml comparing with free CDDP treatment and showed less tube formation amounts (<i>p</i> < 0.01) than free CDDP in matrigel angiogenesis inhibition assay <i>in vitro. …”

Replacement of Conventional Vegetable Oil with Granulated Fats of Palm Oil (Prilled Fats and Calcium Soaps) in Broiler Chicken Diet: Performance and Carcass Traits by OG Nájera-Pedraza (10447476)

“…Throughout the study, CaSPO did not influence feed intake (main effect; p>0.50), but decreased weight gain and had a negative effect on feed conversion (main effects; p<0.05). …”

DataSheet1_Carbon nanostructures supported on Co/serpentinite for sulfentrazone removal.docx by Emilay Baessa Teixeira Diogo (18588691)

“…The removal capacity obtained experimentally at a sulfentrazone concentration of 50 mg L⁻¹ was equal to 14.9 mg g⁻¹. …”

At clinically relevant concentrations the anaesthetic/amnesic thiopental but not the anticonvulsant phenobarbital interferes with hippocampal sharp wave-ripple complexes-5 by Costas Papatheodoropoulos (78587)

“…Note that under thiopental SPWs are prolonged and ripple episode was shortened, containing decreased number of ripple waves. Calibration bars in the inserts: 50 μV, 25 ms for SPW; 25 μV, 50 ms for ripples. . …”

Linearity, depth resolution, and concentration quenching. by Sangly P. Srinivas (1967464)

“…<b>Panel B</b>: Fluorescence <i>vs</i>. depth profiles obtained with fluorescein at 1, 10, and 50 μM solutions. Unlike the fluorescence profile for 1 μM solution (thin line), the fluorescence for 50 μM (thick line) decreases with increasing depth, indicating concentration quenching. …”

Performance, ingestive behavior and carcass traits of lambs fed rations containing soybean cake by Adílson Sponchiado (6673829)

“…Treatments were the inclusion of 50, 100 or 150 g kg-1 of soybean cake in the ration, on a DM basis, and a control diet without this ingredient. …”

Molecular changes following treatment of KNS42 pediatric glioblastoma cells with PI-103. by Nada M. S. Al-Saffar (454143)

“…<p>(A) Representative flow cytometry analysis histograms showing cell cycle distribution of cells with vehicle treatment (DMSO, control, light grey), or following treatment with PI-103 (5×GI₅₀, dark grey) at 8, 12, 24 or 48 hours post treatment. …”

Molecular changes following treatment of SF188 pediatric glioblastoma cells with PI-103. by Nada M. S. Al-Saffar (454143)

“…<p>(A) Representative flow cytometry analysis histograms showing cell cycle distribution of cells following vehicle treatment (DMSO, control, light grey), or treatment with PI-103 (5×GI₅₀, dark grey) at 8, 16 or 24 hours post treatment. …”

Image_1_Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway.JPEG by Leigh Dairaghi (5591222)

“…Chronic treatment of nasal explants with CR-50, an antibody known to interfere with Reelin homopolymerization and Dab1 phosphorylation, decreased the distance GnRH neurons and OECs migrated. …”

Image_2_Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway.TIF by Leigh Dairaghi (5591222)

“…Chronic treatment of nasal explants with CR-50, an antibody known to interfere with Reelin homopolymerization and Dab1 phosphorylation, decreased the distance GnRH neurons and OECs migrated. …”

Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy by Nicole F. Liachko (669572)

“…Among the validated genes we focused on, one of the most consistent genetic modifier genes protecting against pTDP accumulation and motor deficits was the heparan sulfate-modifying enzyme <i>hse-5</i>, the <i>C</i>. …”

<b><i>PNLIPRP1</i></b><b> hypermethylation in exocrine pancreas links type 2 diabetes and cholesterol</b><b> metabolism</b> by Lucas Maurin (19346158)

“…<p dir="ltr"><b>Abstract:</b></p><p dir="ltr">We postulated that T2D predisposes to exocrine pancreatic diseases through (epi)genetic mechanisms. …”

Development of a decision aid for cardiopulmonary resuscitation and invasive mechanical ventilation in the intensive care unit employing user-centered design and a wiki platform fo... by Ariane Plaisance (4856656)

“…We interviewed intensivists individually. Then we conducted three rounds of rapid prototyping involving 15 patients and 11 health professionals. …”

Data_Sheet_1_Lymphocyte trajectories are associated with prognosis in critically ill patients: A convenient way to monitor immune status.pdf by Fei Pei (542729)

“…</p>Results<p>A total of 2022 critically ill patients were unsupervisedly divided into four endotypes based on dynamic ALC, including persistent lymphopenia endotype (n = 1,211; 58.5%), slowly rising endotype (n = 443; 22.6%), rapidly decreasing endotype (n = 281; 14.5%) and normal fluctuation endotype (n = 87; 4.4%). …”

DataSheet_1_Preterm Birth Is Associated With Immune Dysregulation Which Persists in Infants Exposed to Histologic Chorioamnionitis.docx by Gemma Sullivan (11340801)

“…Pro-inflammatory proteins IL-6, MCP-1 and CRP were elevated in the cord blood of preterm infants whilst BDNF, C3, C9, IL-18, MMP-9 and RANTES were decreased, compared to infants born at term. In preterm infants, exposure to HCA was associated with elevations in 8 immune proteins on postnatal day 5 (BDNF, C3, C5a, C9, IL-8, MCP-1, MIP-1β and MMP-9) when compared to preterm infants who were not exposed.…”

Image_2_Modulating sphingosine 1-phosphate receptor signaling skews intrahepatic leukocytes and attenuates murine nonalcoholic steatohepatitis.tiff by Chieh-Yu Liao (6100055)

“…Macrophages, monocytes, NK cells, T cells, NKT cells, and B cells variably express S1P receptors from a repertoire of 5 receptors termed S1P₁ – S1P₅. …”

Image_6_Modulating sphingosine 1-phosphate receptor signaling skews intrahepatic leukocytes and attenuates murine nonalcoholic steatohepatitis.tiff by Chieh-Yu Liao (6100055)

“…Macrophages, monocytes, NK cells, T cells, NKT cells, and B cells variably express S1P receptors from a repertoire of 5 receptors termed S1P₁ – S1P₅. …”