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1
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. Decreased whole body exposure to MG-derived AGEs may be linked to increased weight specific physical activity of HSA-mUCP1 mice. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. Decreased whole body exposure to MG-derived AGEs may be linked to increased weight specific physical activity of HSA-mUCP1 mice. …”
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3
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
Published 2022“…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…”
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Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function
Published 2016“…The HDAC activity reduction was associated with decreased <i>HDAC5</i> / <i>Hdac5</i> and <i>HDAC6</i> / <i>Hdac6</i> expression in human and mice adipocyte fraction. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer
Published 2022“…<p dir="ltr">In tumor-bearing mice, cyclic fasting or fasting-mimicking diets (FMD) enhance the activity of antineoplastic treatments by modulating systemic metabolism and boosting antitumor immunity. …”
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Utilization of the internet for physical activity and diet information and its influence on pregnant women’s lifestyle habits in Qatar
Published 2023“…Among the participants, 54.5% used the internet to obtain information about PA, while 72% sought online diet-related information. …”
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Food purchase and eating behavior during the COVID-19 pandemic: A cross-sectional survey of Russian adults
Published 2021“…Indeed, the survey results suggested (i) a change in the modality of acquiring food, consumers reduced the number of shopping trips and buying more on each trip to minimize store visits; (ii) a surge of stockpiling of non-perishable food items; (iii) a shift toward healthier diets; (iv) an increase in culinary capabilities; (v) a decrease of food waste. …”
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Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury
Published 2024“…Traumatic brain injury (TBI) and lifestyle habits such as Western diet (WD) consumption represent two risk factors that affect an individual's health outcome globally. …”
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Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses
Published 2023“…Meta-analyses included 19 studies for V̇ O<sub>2max</sub>, eight for peak power output from V̇ O<sub>2max</sub> testing (PPO), and five for threshold power (powerAT). …”
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Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet
Published 2023“…Data showed that higher doses of <i>Hibiscus rosa-sinensis</i> significantly reduced the rat's BMI (0.50 g/cm<sup>2</sup>) in comparison with the high-fat–sugar diet group (0.79 g/cm<sup>2</sup>). All treatment groups, especially H-500 group, showed a significant decrease in the elevated kidney and liver weights and atherogenic index in comparison with HFSDC groups. …”
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Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021
Published 2024“…The estimated number of stillbirths occurring at 20 weeks' gestation or longer decreased from 5·08 million (95% UI 4·07–6·35) in 1990 to 3·04 million (2·61–3·62) in 2021, corresponding to a 39·8% (31·8–48·0) reduction, which lagged behind a global improvement in neonatal deaths of 45·6% (36·3–53·1) for the same period (down from 4·03 million [3·86–4·22] neonatal deaths in 1990). …”
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
Published 2019“…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”
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BRET-based biosensors for SARS-CoV-2 oligonucleotide detection
Published 2024“…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …”
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Average Model-Based Feedforward and Feedback Control for PUC5 Inverter
Published 2020“…<p>This paper proposes new average model based control strategies for a 5-level Packed U-cell (PUC5) inverter in both standalone and grid-connected modes of operation. …”
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Impact of staying at home measures during COVID-19 pandemic on the lifestyle of Qatar’s population: Perceived changes in diet, physical activity, and body weight
Published 2021“…Concerning the overall diet perception, 27.8%, and 33.2% perceived that their overall diet has become less healthy, or healthier respectively, since the start of staying at home measures. …”