منشور في 2019
"…While the majority of CPHN cells express (in overall compartments of pancreas) the pan-endocrine transcription factor NKX
2.
2 and beta-cell specific NKX6.1 in comparable frequency in fetal and infant/child cases (81.9 ± 6.3 vs. 82.8 ± 3.8% NKX6.1+-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.9; 88.0 ± 4.7 vs. 82.1 ±
5.3% NKX
2.
2+-CPHN cells of total CPHN cells, fetal vs. infant/child, p = 0.4), the frequency of clustered CPHN cells expressing NKX6.1 or NKX
2.
2 is lower in infant/child vs. fetal cases (1.
2 ± 0.3 vs. 16.7 ± 4.7 clustered NKX6.1+-CPHN cells/
mm2, infant/child vs. fetal, p < 0.01;
2.7 ± 1.0 vs. 16.0 ± 4.0 clustered NKX
2.
2+-CPHN cells/
mm2, infant/child vs. fetal, p < 0.01).…"