بدائل البحث:
akt decrease » _ decrease (توسيع البحث)
nm decrease » _ decrease (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
_ points » _ point (توسيع البحث), a point (توسيع البحث), 5 point (توسيع البحث)
_ akt » _ art (توسيع البحث)
akt decrease » _ decrease (توسيع البحث)
nm decrease » _ decrease (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
_ points » _ point (توسيع البحث), a point (توسيع البحث), 5 point (توسيع البحث)
_ akt » _ art (توسيع البحث)
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
منشور في 2019"…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …"
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Structural evaluation, preliminary in vitro stability and electrochemical behavior of apatite coatings on Ti6Al4V substrates
منشور في 2016"…In the current work, a sputtering technique was used to develop a 300 nm-thick bone-like apatite layer onto Ti-6Al-4V. …"
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Blue photobiomodulation LED therapy impacts SARS-CoV-2 by limiting its replication in Vero cells
منشور في 2021"…Our in vitro findings could represent the starting point for translational applications of PBMT as a supportive approach to fight SARS-CoV-2.…"
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The mitochondrial-related effect of the 905 nm photobiomodulation therapy on 50B11 sensory neurons
منشور في 2023"…In this study, a possible molecular mechanism of the 905 nm PBMT (0.25 W/cm2; 3, 6, 12, and 18 J/cm2, 5 Hz) analgesic effect was tested on 50B11 cells, by investigating its impact on mitochondria. …"
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Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines
منشور في 2018"…Antitumor activity of greensporone C (GC), a new resorcylic acid lactone isolated from an organic extract of a culture of a Halenospora sp. freshwater fungus, was subjected for screening against a panel of leukemic cell lines (K562, U937, and AR320). …"
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Tailoring the defects of sub-100 nm multipodal titanium nitride/oxynitride nanotubes for efficient water splitting performance
منشور في 2021"…Herein, we rationally designed uniform and aligned ultrathin sub-100 nm multipodal titanium nitride/oxynitride nanotubes (TiONxNTs) (x = 2, 4, and 6 h) via the anodic oxidation of Ti-foil in a formamide-based electrolyte followed by annealing under ammonia gas for different durations. …"
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Opportunities, challenges and trade-offs with decreasing avoidable food waste in the UK
منشور في 2021"…This study looks at the main stages of the food supply chain, and amasses the opportunities, challenges and trade-offs associated with surplus food redistribution to the UK economy. It highlights points in the food system where interventions can be made, to improve food’s circularity and sustainability potential. …"
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
منشور في 2021"…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …"
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احصل على النص الكامل
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
منشور في 2021"…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …"
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Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar
منشور في 2023"…Conclusion The conclusion of the first omicron wave was a turning point in the severity of the pandemic. …"
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Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells
منشور في 2017"…Failure of PE to induce PC3 damage in cells overexpressing Akt further confirms its implication in the PE-elicited cell death. …"
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A quality of experience-aware association algorithm for 5G heterogeneous networks
منشور في 2017"…Under these circumstances, the MNOs need to guarantee the users' Quality of Experience (QoE) requirements, while ensuring the sustainability of a 5G investment. To this end, we consider a 5G Heterogeneous Network (HetNet) deployment where MNOs use a QoE-based charging scheme. …"
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Hyperhydration-induced decrease in urinary luteinizing hormone concentrations of Male athletes in doping control analysis
منشور في 2019"…Baseline urinary LH concentrations, expressed as the mean � SD for each individual, were within the acceptable physiological range (7.11 � 5.42 IU/L). A comparison of the measured LH values for both hyperhydration phases (Phase A: 4.24 � 5.60 IU/L and Phase B: 4.74 � 4.72 IU/L) with the baseline (''normal'') values showed significant differences (Phase A: p < .001 and Phase B: p < .001), suggesting the clear effect of urine dilution due to hyperhydration. …"
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Uncovering the Epigenetic Contribution of Protein Arginine Methyltransferase 5 (PRMT5) during Zebrafish Cardiomyogenesis
منشور في 2020"…The reduction of the expression of PRMT5 also resulted in a 4-fold decrease in the rate of hatching and had negative impacts on locomotion and tail flicking in PRMT5 morphants. …"
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Understanding the False Positive of Modified Martensitic Steels in Sweet & Sour Service Conditions Using a Point Defect Model Perspective
منشور في 2023"…These results indicate a critical point in temperature in the tests with only CO2, where resistance to pitting susceptibility is maximized due to a decrease in the cation vacancy diffusivity.…"
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