Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway حسب Olfa Khalifa (10914452)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/s41598-022-06143-5" target="_blank">https://dx.doi.org/10.1038/s41598-022-06143-5</a></p>…"

The effect of type and combination of fertilizers on eukaryotic microbiome of date palm rhizosphere حسب Sara H. Al-Hadidi (17821196)

"…Samples were collected from one wild population, five cultivars from two farms, and a factorial fertilizer experiment (organic, chemical, and biofertilizer) in Qatar. …"

Effects of visual field impairment on driving حسب Jan Andersson (218600)

"…Reaction time for double stimuli trials was 15% longer (1,68s vs. 1.46s) and hit rate was 27% less (69% vs. 88%). When the results from a secondary trial for drivers visual impairments were compared the normal sighted drivers’ first try the differences decreased but were still statistical significant. …"

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... حسب Samar Shurbaji (9938696)

"…</p><h3>Methods </h3><p dir="ltr">102 fingerstick, venepuncture whole-blood, and serum samples (with normal and abnormal TSH values) were analyzed by Finecare™ Rapid Quantitative LFIA test and Roche cobas® e 601 as a reference test. </p><h3>Results </h3><p dir="ltr">Using serum, when compared to cobas® e 601 reference method, Finecare™ showed high sensitivity [90.5 % (69.6–98.8)] and specificity [96.3 % (89.6–99.2)] for diagnosis of thyroid abnormalities (<0.35 or >4.5 mIU/L). …"

Technical assessment of different extraction methods and transcriptome profiling of RNA isolated from small volumes of blood حسب Mahesh Kumar Reddy Kalikiri (17886695)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/s41598-023-30629-5" target="_blank">https://dx.doi.org/10.1038/s41598-023-30629-5</a></p><p dir="ltr">Additional institutions affiliated with: Integrated Genomics Services - Sidra Medicine</p>…"

Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills حسب Tariq Abbas (368053)

"…Additionally, the mean power spectral density of the EMG signal decreased notably post-training. </p><h3>Conclusion</h3><p dir="ltr">This study presents a structured approach for hypospadias training and highlights the effectiveness of wearable sensor technology for objective skill assessment. …"

Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats حسب Maisa Siddiq Abduh (16381125)

"…Group IV (PAR) received 600 mg/kg of PAR orally; V (PAR + IL-35) and VI (PAR + TYHO); rats received 600 mg/kg of PAR orally and i.p injection of IL-35 (200 ng/kg) or THYO (0.5 mg/kg), respectively. …"

Photocatalytic deposition of cobalt atoms on two-dimensional nanocomposites as efficient visible-light-driven photocatalysts: Experimental study and intelligent modeling حسب Salar Heydari Shalmani (22589851)

"…The active species scavenging tests also showed that OH• and h+ were the main species involved in the degradation of TC. The Co(76)/TNs /rGO(5) sample recovery and reusage experiments did not show a significant reduction in the photocatalytic performance after five consecutive cycles. …"

Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels حسب Haya Al-Sulaiti (5449256)

"…Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. Additionally, a decrease in glycochenodeoxycholic acid levels was also triggered by treatment with AuNPs, suggesting modulation of bile acid metabolism with potential effects on lipid homeostasis. …"

Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer حسب Adviti Naik (673163)

"…Following <i>LDHC</i> knockdown, we observed an increase in the secretion of tumor-derived pro-inflammatory cytokines (IFN-γ, GM-CSF, MCP-1, CXCL1), a decrease in the soluble levels of tumor-derived immunosuppressive factors (IL-6, Gal-9) and reduced tumor cell surface PD-L1 expression. …"

Resilience-uncertainty nexus in building energy management integrated with solar system and battery storage حسب Hasan Mehrjerdi (16869957)

"…The energy planning excluding uncertainty and events may be economically efficient but it is not resilient and practical. This paper provides a platform for energy management in the building under a set of realistic failures and uncertainties. …"

Custom foot orthoses improve performance, but do not modify the biomechanical manifestation of fatigue, during repeated treadmill sprints حسب Olivier Girard (409080)

"…</p><h3>Results</h3><p dir="ltr">Distance ran in 5 s decreased from first to last sprint (<i>P</i> < 0.001), yet with higher sprints 1–8 values for both EVA (<i>P</i> = 0.004) and TPU (<i>P</i> = 0.018) versus CON. …"

Techno-economic and environmental analyses of the pyrolysis of food waste to produce bio-products حسب Mohammad Alherbawi (14155767)

"…In terms of product yields, all three systems (single, binary, and tertiary) followed a similar pattern: bio-oil yields increased as temperature and feedstock moisture content increased, while biochar yields decreased as temperature and feedstock moisture content increased. …"

Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines حسب Najlah, Mohammad

"…The aim of this study is to investigate using nanoemulsion formulations as drug-delivery vehicles of paclitaxel (PX), a poor water-soluble anticancer drug. Two commercially available nanoemulsion fat formulations (Clinoleic 20% and Intralipid 20%) were loaded with PX and characterised based on their size, zeta potential, pH and loading efficiency. …"
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Solar syngas production via methanothermal reduction of strontium oxide حسب Rahul R. Bhosale (6467102)

"…<p dir="ltr">A solar methanothermal reduction of strontium oxide for the co-production of Sr and syngas is thermodynamically explored. …"

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 حسب LBD Double Burden of Malnutrition Collaborators (18567880)

"…Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. …"

Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity حسب Qinji Zhou (18513741)

"…In conclusion, Celsr3 is required for PCs maturation and regulates postsynaptic LTP and LTD through Wnt5a/cAMP and mGluR1/PKCα signaling respectively.…"

Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data حسب Majdoleen Alalawneh (13961580)

"…Within BMI categories, a similar increasing trend was observed in underweight, normal, and overweight patients, while from 2018 to 2020, there was a decreasing trend in rivaroxaban prescribing in all obese classes. …"

The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i> حسب Safa Salim (9186786)

"…Moreover, Ssdp overexpression led to differential changes in synaptic density in specific brain regions. We observed decreased levels of armadillo in the heads of Ssdp overexpressing flies, as well as a decrease in armadillo and wingless expression in the larval wing discs, implicating the involvement of the canonical Wnt signaling pathway in Ssdp functionality. …"

Application of Fe₃O₄ magnetite nanoparticles grafted in silica (SiO₂) for oil recovery from oil in water emulsions حسب Wamda Faisal Elmobarak (17058024)

"…Using an MD_dose as low as 10 mg/L attained a %_hdem in the range of 93% - 4.3% for O/W mixtures with C_oil < 2000 mg/L, which slightly decreased to ~90% for higher concentrations. …"