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CRISPR-Cas Controls Cryptic Prophages
Published 2022“…<div><p>The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. …”
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Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane
Published 2024“…In addition, Differential scanning calorimetry (DSC)exhibited a decrease in glass transition temperature (Tg) from S1 to S10, resulting in a corresponding reduction in the rate of shape restoration. …”
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Effect of speed and gradient on plantar force when running on an AlterG® treadmill
Published 2021“…Gradient made little difference except for a downhill grade of − 5% decreasing force peaks as compared to level or uphill running.…”
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth
Published 2021“…A step further is now required to determine whether these platform foundations should be converted to reefs after their decommissioning (i.e., Rigs to Reefs approach).…”
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352
Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
Published 2023“…</p> <p>Results: The BCAA-restricted diet significantly reduced circulating BCAA concentrations by ~50% i.e., baseline 437 ± 60 to 217 ± 40 µmol/L (p < 0.005). …”
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Wasted Da’am: Evaluating the Impact of Food Waste Management Practices on the Environment in Hotels in Qatar
Published 2025“…This thesis examines the impact of food waste management strategies on the environment in hotels in Qatar, utilizing a difference-in-differences regression analysis and in-depth interviews with executive chefs in 5-star hotels in Lusail and Msheireb, Qatar. …”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…</p><h3>Results</h3><p dir="ltr">The data demonstrated that the continuous‐bout‐duration (1 × 12 min) of 4vs4 and 3vs3 SSGs was characterized by a significant decrease in total mood disturbance (TMD) compared to 2 × 6 min and 3 × 4 min (4vs4:<i>p</i> < 0.01; 3vs3:<i>p</i> < 0.001). …”
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The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature
Published 2021“…Short-term (i.e., 10-24 weeks) moderate- to high-intensity strength training reduced LPS–IL-6, LPS, IL-1β, LPS–TNF-α and circulating concentrations of TNF-α and increased IL-10 in healthy elderly women and older people with cognitive impairment, respectively. …”
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
Published 2022“…The progress seen in children younger than 5 years was clearly a result of targeted interventions, such as vaccination and reduction of exposure to risk factors. …”
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Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles
Published 2024“…The hydrophilicity of PSf membranes was improved by adding of ZnO and doped ZnO NPs which showed a decrease in contact angle values from 82° to 62° with an increased flux with water. …”
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Solar hydrogen production via thermochemical magnesium oxide – Magnesium sulfate water splitting cycle
Published 2020“…Overall analysis confirms that although the rise in the molar flow rate of Ar from 1 to 50 mol/s results in a decrease in the thermal reduction temperature from 1490 K to 1282 K, the solar-to-fuel energy conversion efficiency is adversely affected and reduces from 47.7% to 18.1%. …”
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Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17
Published 2020“…For sewer or septic sanitation, access was 46·3% (95% UI 46·1–46·5) in 2017, compared with 28·7% (28·5–29·0) in 2000. …”
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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…Finally, as a definitive and specific way to modulate SLFN11 expression we implemented SLFN11 dCas9 (dead CRISPR associated protein 9) systems to specifically increase or decrease SLFN11 expression.…”