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241
Engineering Novel Single-chain Variable Fragments for Therapeutic and Diagnostic Approaches in Parkinson's Disease
منشور في 2019"…Six different scFv cDNA constructs, containing either cell-penetrating peptide (CPP), 12-Arginine, or no peptide, were cloned in <i>E. coli</i> expression constructs with or without GST tag. …"
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242
Association between thermal responses, medical events, performance, heat acclimation and health status in male and female elite athletes during the 2019 Doha World Athletics Champi...
منشور في 2022"…Athletes (63%) who performed 5–30 days heat acclimation before the competition: ranked better (18±13 vs 28±13, p=0.009), displayed a lower peak T<sub>core</sub> (39.4°C±0.4°C vs 39.8°C±0.7°C, p=0.044) and larger in-race decrease in T<sub>skin </sub>(−1.4°C±1.0°C vs −0.9°C±1.2°C, p=0.060), than non-acclimated athletes. …"
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243
Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
منشور في 2020"…In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …"
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Biomolecular alterations in acute traumatic brain injury (TBI) using Fourier transform infrared (FTIR) imaging spectroscopy
منشور في 2021"…<p dir="ltr">Acute injury is one of the substantial stage post-traumatic brain injury (TBI) occurring at the moment of impact. …"
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
منشور في 2022"…The progress seen in children younger than 5 years was clearly a result of targeted interventions, such as vaccination and reduction of exposure to risk factors. …"
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247
CRISPR-Cas Controls Cryptic Prophages
منشور في 2022"…<div><p>The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages. …"
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248
Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane
منشور في 2024"…In addition, Differential scanning calorimetry (DSC)exhibited a decrease in glass transition temperature (Tg) from S1 to S10, resulting in a corresponding reduction in the rate of shape restoration. …"
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249
Effect of speed and gradient on plantar force when running on an AlterG® treadmill
منشور في 2021"…Gradient made little difference except for a downhill grade of − 5% decreasing force peaks as compared to level or uphill running.…"
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Utilization of the internet for physical activity and diet information and its influence on pregnant women’s lifestyle habits in Qatar
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">A total of 327 pregnant women (mean age of 29.5 years ± 4.0) completed and returned the questionnaire (response rate: 87.5%). …"
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253
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
منشور في 2020"…Induction of apoptosis by VCX treatment induced cell cycle arrest at G0/G1 phase with inhibition of cell proliferator genes, cyclin D1 and E2F1. …"
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254
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"
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255
Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
منشور في 2023"…</p> <p>Results: The BCAA-restricted diet significantly reduced circulating BCAA concentrations by ~50% i.e., baseline 437 ± 60 to 217 ± 40 µmol/L (p < 0.005). …"
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Wasted Da’am: Evaluating the Impact of Food Waste Management Practices on the Environment in Hotels in Qatar
منشور في 2025"…This thesis examines the impact of food waste management strategies on the environment in hotels in Qatar, utilizing a difference-in-differences regression analysis and in-depth interviews with executive chefs in 5-star hotels in Lusail and Msheireb, Qatar. …"
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
منشور في 2025"…</p><h3>Results</h3><p dir="ltr">The data demonstrated that the continuous‐bout‐duration (1 × 12 min) of 4vs4 and 3vs3 SSGs was characterized by a significant decrease in total mood disturbance (TMD) compared to 2 × 6 min and 3 × 4 min (4vs4:<i>p</i> < 0.01; 3vs3:<i>p</i> < 0.001). …"
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258
The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature
منشور في 2021"…Short-term (i.e., 10-24 weeks) moderate- to high-intensity strength training reduced LPS–IL-6, LPS, IL-1β, LPS–TNF-α and circulating concentrations of TNF-α and increased IL-10 in healthy elderly women and older people with cognitive impairment, respectively. …"
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School children growth monitoring program in the state of Qatar: Observations from two survey rounds in 2016–17 and 2019–20
منشور في 2023"…A total of 7514 unique records of students aged 5–14 years available in both survey rounds were included in the final analysis. …"
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Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity
منشور في 2025"…These findings were associated with higher level of oxidative stress (GP91 expression and malondialdehyde level) and elevated expression of key regulators of apoptosis (Bax and caspase-3) as well as reduced expression of mitochondrial respiratory chain complexes SDHB (II), UQCRC2 (III), and ATP5a (V) in the testicular tissue.</p><h3 dir="ltr">Conclusion</h3><p dir="ltr">From these findings, it can be concluded that exposure to AB-FUBINACA can interfere with the normal physiology and functioning of the male reproductive organs. …"