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Regenerating axons are increased by ATRA and decreased by clodronate.
Published 2021“…(E) ATRA and clodronate liposome treatment, composite from 2 sections. Scale bar: 100 μm in A and B. (F) Bar and scatter plots of the number of axons per transverse section, sampled at approximately 200 μm distal to the cut site, showing mean ± SEM. …”
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Repetitive stress induces a decrease in sound-evoked activity.
Published 2025“…(d) Noise-evoked activity rates at different noise intensities for chronically tracked PV cells in baseline and repeated stress conditions (<i>N</i> = 5 mice, <i>n</i> = 31 neurons, mean ± SE). Activity rates decreased during repeated stress compared to baseline (2-way ANOVA, condition F = 49.6, <i>p</i> = 2.6 × 10<sup>−12</sup>, condition: intensity interaction F = 1.94, <i>p</i> = 0.02, nested ANOVA (mouse nested within session), F = 56.5, <i>p</i> = 8.8 × 10<sup>−14</sup>, condition: intensity interaction F = 3.5, <i>p</i> = 3.5 × 10<sup>−05</sup>). …”
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The decrease or inhibition of Hsp90 induced REST degradation.
Published 2019“…<p>(A) Effect of Hsp90α ASO on cell viability. Differentiated SH-SY5Y cells were transfected with different concentrations of Hsp90α ASO. …”
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