Development of a CRISPR/Cas-Based Detection Platform for Tracking Decreased Susceptibility to Cephalosporins in Neisseria gonorrheae by Ziyuan Zhao (2889005)

“…Developing efficient and accurate detection of resistant strains is urgently needed for their management and treatment. We have developed the Multiplex Integrated RPA-CRISPR/Cas12a detection Assay (MIRCA) for simultaneous detection of Neisseria gonorrheae (<i>Ng</i>) and mutations with decreased susceptibility to cephalosporins. …”

Diabetic wounds show increased amounts of vessel leakage and decreased pericyte coverage. by Uzoagu A. Okonkwo (8754933)

Decreased transcription of <i>prs</i> results in decreased growth. by Javiera Norambuena (137228)

Evaluation of <i>in vitro</i> activity of LNP-siRNA on LX-2 cells stimulated by 2 ng/mL of TGF-β. by Ying-Chou Chen (263436)

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Inhibition of PKC or Rho protein kinase decreases Ad5 wild type replication <i>in vitro</i>. by Alice Liu (4814415)

Attenuation of TNF-α-induced apoptosis by DEX pretreatment. by Byung Chul Kang (1905025)

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Analytical sensitivity and reproducibility. by Lizhi Yu (12476136)

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PGRN decreased Dectin-2 expression on the surface of macrophages and neutrophils. by Jiayu Liu (3951515)

IL-15 decreased early apoptosis of α-GalCer-treated iNKT cells in SLE patients. by Chien-Ya Hsu (11868746)

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JC-1 monomer increased with the stimulation of sFlt-1 and decreased after administration of Z-LEHD-FMK in HUVECs. by Yaling Zhai (9239458)

<b>Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decrease ISR activation in DRG neurons</b> by Muhammad Saad Yousuf (20745168)

Decrease in circulating iNKT cell activation during regadenoson (RA) infusion into patients with COVID-19. by Joseph Rabin (7399436)

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Figure 5 from Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin by Joanna Domagala (21643925)

“…NK cells were primed with IL2 (200 U/mL) and IL15 (10 ng/mL) for 24 hours before the experiment. <b>G,</b> The level of perforin detected in NK cells incubated with NH₄Cl and other lysosomotropic agents [chloroquine (CQ), concanamycin (CMA), and monensin] for 4 hours determined by intracellular staining using antibodies detecting total perforin (B-D48 clone) and lysosomal perforin (δG9 clone; <i>n</i> = 2). …”

Delphinidin alters VEGF-A splicing to increase VEGF-A₁₆₅b and decrease total VEGF-A expression. by Megan Stevens (3964886)

“…<p><b>A)</b> Treatment of podocytes with delphinidin chloride (10 μg/ml) under normal glucose (NG; 5 mM glucose + 25 mM mannitol) and high glucose (HG; 30 mM glucose, 1 ng/ml TNFα, 1 ng/ml IL-6, and 100 nM insulin) for 48 hrs increased the protein expression of VEGF-A₁₆₅b relative to total VEGF-A₁₆₅ (quantified in <b>B</b>; *p<0.05 vs NG, †p<0.05 vs HG; n = 3 biological repeats; One-way ANOVA with Bonferroni post-hoc test for comparison between pairs; <b>A</b>—the same blot was first probed with VEGF-A₁₆₅b before stripping and reprobing with panVEGF-A). …”

Comparison of ∑PBB, ∑BDE, ∑PCN and ∑DDT concentrations and concentrations of some congeners in eggs analyzed in this study and other relevant studies (ng/g ww, geometric mean and r... by Matti Viluksela (321291)

<b>Glucagon Clearance is Decreased in Chronic Kidney Disease, but Preserved in Liver Cirrhosis</b> by Magnus F. G. Grøndahl (19160825)

Decrease in vRNA in brain during antiretroviral therapy. by Sonny R. Elizaldi (9684796)

BA decreases mitochondrial membrane potential and superoxide production after one day of cell culture. by Bandik Föh (602419)

“…(G) Representative contour plots of CD138 and IL-10 GFP expression in isolated splenic B cells from IL-10 reporter mice after treatment with 0.5 mM BA and/or 100ng/ml PMA. …”

NgR1 KO mice exhibited an increase in excitatory synapses and a decrease in inhibitory synapses, indicating an imbalance of synaptic transmission. by Jinwei Zhang (462455)

“…The inhibitory synaptic density of NgR1 mice showed a significant decrease when compared to WT mice (***P <  0.001). …”

Sulforaphane decreases IL-6, TNF-α, IL-17, and total IgG levels. by Su-Jin Moon (424173)