Image_2_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.tif by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Table_4_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Table_1_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Image_1_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.tif by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Table_3_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Cumulative distribution function of the WEED distribution for <i>β</i> = 0.5, 1, 1.5, and 2 in circular representation. by Sakhr A. S. Alotaibi (22216601)

FUD transiently decreased IOP in mice injected with Ad5-TGFβ2 viral vector. by Jennifer A. Faralli (4907311)

“…FUD significantly decreased IOP on Day 17 (2 days after it was injected on Day 15; *p<0.05). n = 6, 15, 13 and 12 for TGFβ2 only, TGFβ2 + FUD, TGFβ2 + PBS and TGFβ2 + mFUD treated eyes respectively. …”

A flow diagram of the study entry. by Sakiko Fukui (387048)

“…</p><p>Methods</p><p>Sixty-nine deceased older adults from five special nursing homes were studied over 3.5 years (January 2016 to June 2020). …”

<i>GmNN1/FT2a</i> expression analysis. by Xinxin Li (281237)

Repetitive stress induces a decrease in sound-evoked activity. by Ghattas Bisharat (20706928)

“…<p>(a) Left: noise-evoked activity rates at different noise intensities for chronically tracked PPys cells in baseline and repeated stress conditions (<i>N</i> = 5 mice, <i>n</i> = 285 neurons, mean ± SE). …”

Data_Sheet_5_Chronic Neurobehavioral Impairments and Decreased Hippocampal Expression of Genes Important for Brain Glucose Utilization in a Mouse Model of Mild TBI.xlsx by Linda M. Huynh (9395591)

GSK343 decreased viability and proliferation in human neuroblastoma PDX cells. by Laura V. Bownes (10276762)

“…Treatment with GSK343 resulted in significantly decreased migration. (D) After 24 hours of treatment with increasing concentrations of GSK343 (0, 5, 10 μM), COA3 and COA6 cells (4.0 × 10⁴) were plated in Transwell^® inserts and allowed to invade for 1 week through a Matrigel^™ layer. …”

DataSheet_1_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.zip by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

IMR90 fibroblasts bind SARS-CoV-2 spike and <i>LRRC15</i> over-expressing fibroblasts show decreased Collagen VI expression. by Lipin Loo (462678)

“…<i>LRRC15</i> overexpression in fibroblasts results in decreased Collagen VI protein expression. …”

Gas-Phase-like Inertial Rotation of a Platonic Solid in Reticular Amphidynamic Crystals of CUB-5: Molecular Dynamics and Experiment by Jing-Ran Shan (16641931)

“…Through quantum mechanical (QM) calculations and molecular dynamics (MD) simulations we verified that nearly barrierless cubane rotators in CUB-5 display rotational dynamics that transitions from continuous or inertial at high temperature, to chaotic behavior, and ultimately to discrete jumps, as the temperature decreases from room temperature down to cryogenic conditions. …”

Fig 5 - by Yanting Wang (104823)

Antinociceptive effect of N-(9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-yl)-2-hydroxybenzamide on different pain models in mice by Hee-Jung Lee (297255)

“…<div><p>Abstract N-(9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-yl)-2-hydroxybenzamide (DDIAHB) is a new drug developed through molecular modelling and rational drug design by the molecular association of epinastine and salicylic acid. …”

Functional metabolism pathways present at ≥ 0.5% mean relative abundance in Control calves (n = 15) and High-Se treatment calves (n = 15) after weaning (baseline; week 0), at the e... by Jean A. Hall (289030)

Data_Sheet_1_TMPRSS2 gene polymorphism common in East Asians confers decreased COVID-19 susceptibility.docx by Takeshi Sekiya (14194334)

Cardamonin induced apoptosis and decreased the MMP of ovarian cancer cells. by Peiguang Niu (17044532)