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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
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The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl
منشور في 2021"…The city of Sharjah is among the Gulf cities that have increased in size at an unprecedented rate by all standards, and within a period of time not exceeding four decades, after it remained confined within its old wall since its inception until the beginning of the seventies of the last century, with an area of 2.5 square kilometers. …"
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Wales’ tourists not a burden for local healthcare
منشور في 2016"…</p><p>Instead, they found that Welsh residents were responsible for the vast majority of unintentional injury presentations to the emergency department. They also found a decrease in non-resident presentations between 2006 and 2014, the data range that was studied.…"
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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
منشور في 2024"…Forecasts for the reference scenario found that health will improve in the coming decades, with all-cause age-standardised DALY rates decreasing in every GBD super-region. The total DALY burden measured in counts, however, will increase in every super-region, largely a function of population ageing and growth. …"
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The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 20...
منشور في 2020"…Methods We modelled mortality due to IBD using a standard Cause of Death Ensemble model including data mainly from vital registrations. …"
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The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global...
منشور في 2020"…<p>Background Oesophageal cancer is a common and often fatal cancer that has two main histological subtypes: oesophageal squamous cell carcinoma and oesophageal adenocarcinoma. …"
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The impact of maternal care on child development
منشور في 2019"…Results show that treated children enjoy an increase of 3.6 h per week in the time they spend with their mothers, mainly due to a decrease in the time spent in non-institutional care. …"
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Removal of bacterial contaminants and antibiotic resistance genes by conventional wastewater treatment processes in Saudi Arabia: Is the treated wastewater safe to reuse for agricu...
منشور في 2015"…A culture-based approach further revealed that Pseudomonas aeruginosa was mainly found in the influent and non-chlorinated effluent but was replaced by other Pseudomonas spp. in the chlorinated effluent. …"
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Structural performance of buried prestressed concrete cylinder pipes with harnessed joints interaction using numerical modeling
منشور في 2016"…Performance indicators in the various components of PCCP are monitored as internal pressure is increased. A sensitivity analysis is presented for how manipulating the severity of the damage affects the failure pressure of the pipe. …"
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Crunching the numbers of food poisoning in Qatar
منشور في 2016"…Three-fourths of the cases in that same year were non-Qataris, with Indians, Egyptians and Pakistanis forming a large bulk of those affected. …"