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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
منشور في 2023"…Finally, as a definitive and specific way to modulate SLFN11 expression we implemented SLFN11 dCas9 (dead CRISPR associated protein 9) systems to specifically increase or decrease SLFN11 expression.…"
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263
Nanospace-engineered carbons for reversible storage of natural gas and hydrogen
منشور في 2011"…Excess adsorption dominated by KOH:C ratio. 2.Volumetric storage capacity decreases with increasing activation temperature. 3. 2.5K activated at 700 oC has record volumetric storage capacity of 132 g CH4/liter carbon at 35 bar and 22 oC (200 V/V, 110% of DOE target of 118 g/liter). …"
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conferenceObject -
264
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265
Subsarcolemmal cAMP signals monitored by cyclic nucleotide gated channels in hypertrophied cardiac myocytes
منشور في 2005"…Cumulative concentrationresponse curve to the non-selective E-adrenergic agonist isoprenaline (Iso) indicated a 33% decrease of the maximal cAMP accumulation produced by Iso while the effect of the hydrosoluble forskolin analog, L-858051 at a saturating concentration (100 µM) was unchanged between the two groups. …"
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266
An additive manufacturing approach based on electrohydrodynamic printing to fabricate P3HT:PCBM thin films
منشور في 2023"…The films exhibited a broad visible absorption spectrum ranging from ~ 340 to ~ 600 nm, with a maximum peak λ<sub>max</sub> located at ~ 500 nm. …"
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267
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268
Influenza prevalence and vaccine efficacy among diabetic patients in Qatar
منشور في 2023"…Among the typed IVA-positive cases, 33.4% were H1N1, and 7.7% were H3N2. A significant decrease in influenza infections was reported in vaccinated DM patients (14.5%) when compared to non-vaccinated patients (18.9%) (p-value = 0.006). …"
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269
Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity
منشور في 2025"…These findings were associated with higher level of oxidative stress (GP91 expression and malondialdehyde level) and elevated expression of key regulators of apoptosis (Bax and caspase-3) as well as reduced expression of mitochondrial respiratory chain complexes SDHB (II), UQCRC2 (III), and ATP5a (V) in the testicular tissue.…"
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270
Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer
منشور في 2017"…Treatment of HaCaT-ras A5 and HaCaT-ras II4 cells with F2 fraction resulted in the accumulation of cells in the sub-G1 apoptotic phase and decreased the population of cells in the S and G2/M phases. …"
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article -
271
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
منشور في 2021"…Pt/MgO nanoparticles were cuboid and in the nanosize range of 30–50 nm. The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …"
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272
High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
منشور في 2023"…Conclusion: In comparison to the reference assay, our study demonstrates that Finecare™ exhibits high sensitivity, specificity, agreement, and a strong correlation. These findings provide evidence that Finecare™ is a reliable, valid, and accurate point-of-care test for TSH screening and quantitative measurement, especially in non- or small laboratory settings.…"
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article -
273
Qatar’s immigrants at higher risk of diabetes
منشور في 2015"…Those of South Asian descent had a 13-fold increased risk of having elevated glycated haemoglobin levels, and Filipinos a 4.5-fold increase, compared to the native Arab population. …"
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274
miRNA-dependent regulation of STIM1 expression in breast cancer
منشور في 2019"…</p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/s41598-019-49629-5" target="_blank">https://dx.doi.org/10.1038/s41598-019-49629-5</a></p>…"
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275
Blockchain implementations. (c2019)
منشور في 2019"…Insurers, as is the case with other firms that are not essentially active in the financial sector only, are at present expected to make a decision: adopt blockchain or not, unfortunately with the assessment of whether the investment was right not to be known till within 3–5 years. …"
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masterThesis -
276
Characterizing the dynamics of climate and native desert plants in Qatar
منشور في 2024"…Additionally, vegetation cover varied between protected sites, indicating the complexity of arid lands influenced by factors like topography and soil type. These findings suggest a continued decrease in vegetation coverage, leading to more drought seasons and impacting water and food security. …"
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277
Application of hierarchical oligonucleotide primer extension (HOPE) to assess relative abundances of ammonia- and nitrite-oxidizing bacteria
منشور في 2017"…Our findings indicated a good correlation between the relative abundance of nitrifying bacterial populations obtained using both HOPE and amplicon sequencing. …"
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article -
278
Association between sources of sexuality education, sexual beliefs and behaviours in Lebanese young adults
منشور في 2020"…Sex and classes on reproductive health predicted a rise in SBI. The timing of classes, namely earlier introduction, and communication with family and religious figures predicted a decrease in SBI. …"
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279
Hydrogen energy systems: Technologies, trends, and future prospects
منشور في 2024"…These storage conditions necessitate the development of<u> advanced materials </u>and infrastructure improvements. The findings of this study emphasize the need for comprehensive strategic planning and interdisciplinary efforts to maximize hydrogen's role as a<u> sustainable energy</u> source. …"
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280
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
منشور في 2021"…Pt/MgO nanoparticles were cuboid and in the nanosize range of 30–50 nm. The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …"